Canesten internal 10%

Overdose

Acute overdose due to local application of the drug is unlikely to maintain 10% inside and does not lead to life-threatening situations。

Contraindications

Outer cream, outer powder, solution for external and external use, vaginal gel, vaginal tablets軟膏

Hypersensitivity to drug ingredients。

Hypersensitivity, pregnancy (I am pregnant).

Incompatibilities

Outer cream, outer powder, solution for external and external use, vaginal gel, vaginal tablets軟膏

When used at the same time as angotericin B and nistatin, the durability of clotrimazole may be reduced。

Reduces the effectiveness of nistatin。

Undesirable effects

Outer cream, outer powder, solution for external and external use, vaginal gel, vaginal tablets軟膏

This drug is usually well tolerated。 Rarely, hypersensitivity to the ingredients of a drug focuses on allergic reactions such as redness of the oral mucosa, burning and tingling at the site of application of the drug, and urticaria。

If irritation occurs, the drug should be discontinued。

Allergic reaction: bloodshed, itching, rash.

Therapeutic indications

Outer cream, outer powder, solution for external and external use, vaginal gel, vaginal tablets軟膏

10% oral stomatitis inside Kanessten。

Fungal lesions on skin and mucous membranes caused by filamentous fungi, mold and yeast-like fungi, multicolor lichen, erythrasma, candidiasis vulvovaginitis, trichomoniasis, fungal diseases caused by secondary pyoderma, prenatal Hygiene of the road.

Pharmacotherapeutic group

  • Antifungal agent
  • Other synthetic antibacterial agents

Pharmacodynamic properties

Outer cream, outer powder, solution for external and external use, vaginal gel, vaginal tablets軟膏

Clotrimazole is an imidazole derivative and a wide range of antifungal agents。

The antifungal effect violates the synthesis of ergosterol, which is part of the cell membrane of a fungus, causes changes in its structure and properties, and results in cytolysis。

Against clotrimazole-sensitive skin filamentous fungi and yeast-like fungi (genus) Candida, Torlopsis-Grabrata, Rhodotrula), mold fungi, and multicolored moss causative substances Pitilia Sith-Versicolor And the causative agent of Eritrasma。

It has antibacterial effects against Gram-positive (Staphylococcus and Streptococcus) and Gram-negative bacteria (Bacteroides, Gardnerera-Vaginaris) Even in relation to Trichomonas-Vaginaris

It has a wide range of effects。 It is resistant to the situation, Candida fungi, corynebacterium Minutissimum, and staphylocococcal spp。, Streptococcus。, Trichomonas

Pharmacokinetic properties

Outer cream, outer powder, solution for external and external use, vaginal gel, vaginal tablets軟膏

When applied locally, clotrimazole adsorption from the mucous membrane is negligible。

It is characterized by high penetration。 Concentrations in the epidermis are higher than those in the dermis and subcutaneous tissues。 It has virtually no systemic effect。

Name of the medicinal product

10% inside Kanesten

Qualitative and quantitative composition

Clotrimazole

Dosage (Posology) and method of administration

Cream, skin powder, skin spray, solution軟膏

Outside, The cream is applied to the affected area of the skin 2-3 times in a thin layer and rubbed gently。 In case of deformation, it is split by a row of creams with a palm size and a length of 0.5 cm。

The duration of treatment is individual and depends on the severity and location of the disease。 To achieve full recovery, do not discontinue treatment with cream immediately after the acute symptoms of inflammation or subjective complaints have disappeared。 The treatment period should average about 4 weeks。

Dermatological fungi-3-4 weeks, erythrasma-2-4 weeks, polychromatic lichen-1-3 weeks, Candidiasis vulvitis and glansitis-1-2 weeks。

For fungal diseases of the skin of the legs, it is recommended that treatment be continued for about 2 weeks after the symptoms of the disease are relieved。

Externally, in the vagina, the ointment is applied to the affected area of the skin in a thin layer three times until the autism disappears and for another two weeks。 A single dose is a column of 5 mm with a surface area width distributed at scale。 For vaginal infections-get deep inside the vagina with the applicator once a day。 For Candida vulvovaginitis and Candida glans, 1-2 times a day for 2-3 weeks。 The total duration of treatment for dermatomycosis is 3-4 weeks, erythrasma-2-4 weeks, multicolored lichen-1-3 weeks。