Pharmacy sales terms
According to the recipe.
Pharmacotherapeutic group
- Antimicrobial agent, fluoroquinolone [Quinolones/Fluoroquinolones]
Special precautions for storage
In a place protected from light, at a temperature not exceeding 25 °C.
Keep out of reach of children.
Shelf life of the drug Abactal®3 года.
Do not use after the expiration date indicated on the package.
Nature and contents of container
Concentrate for the preparation of a solution for intravenous administration of 5 ml
| pefloxacin (in the form of mesylate) | 400 mg |
| auxiliary substances: ascorbic acid and 13.6 mg | |
Release formConcentrate for the preparation of a solution for intravenous administration, 80 mg / ml. По 5 мл концентрата для приготовления раствора для в/в введения в ампуле; по 10 амп. в поддоне, по 1 поддону в пачке картонной.
Nosological classification (ICD-10)
- A00 Cholera
- A01 Typhus and paratyphoid
- A01. 1 Paratyph A
- A01. 2 Paratyph B
- A01. 3 Paratyph C
- A02 Other salmonella infections
- A03 Shigellosis
- A04. 0 Enteropathogenic infection caused by Escherichia coli
- A28. 2 Extraintestinal yersiniosis
- A39. 0 Meningococcal meningitis
- A54 Gonococcal infection
- A56 Other sexually transmitted chlamydia diseases
- D84. 9 Immunodeficiency, unspecified
- G00 Bacterial meningitis, not classified elsewhere
- G00. 9 Bacterial meningitis, unspecified
- G03. 9 Meningitis, unspecified
- H70 Mastoiditis and related conditions
- I33. 0 Acute and subacute infectious endocarditis
- J01 Acute sinusitis
- J06 Acute upper respiratory tract infections of multiple and unspecified localization
- J18 Pneumonia without specifying the causative agent
- J20 Acute bronchitis
- J22 Acute respiratory infection of the lower respiratory tract, unspecified
- J32 Chronic sinusitis
- J42 Chronic bronchitis, unspecified
- J47 Bronchiectatic disease [bronchiectasis]
- K65 Peritonitis
- K65. 8 Other types of peritonitis
- K81 Cholecystitis
- K83. 0 Cholangitis
- K85 Acute pancreatitis
- K86. 1 Other chronic pancreatitis
- L08. 9 Local infection of the skin and subcutaneous tissue, unspecified
- L98. 9 Skin and subcutaneous tissue damage, unspecified
- M00. 9 Pyogenic arthritis, unspecified (infectious)
- M79. 8 Other specified soft tissue lesions
- M86 Osteomyelitis
- M89. 9 Bone disease, unspecified
- N10 Acute tubulointerstitial nephritis
- N11 Chronic tubulointerstitial nephritis
- N12 Tubulointerstitial nephritis, not specified as acute or chronic
- N39. 0 Urinary tract infection without established localization
- N41 Inflammatory diseases of the prostate gland
- N45 Orchitis and epididymitis
- N45. 9 Orchitis, epididymitis and epididymo-orchitis without mention of abscess
- N49 Inflammatory diseases of the male genitals, not classified elsewhere
- N70 Salpingitis and oophoritis
- N71 Inflammatory diseases of the uterus, other than the cervix
- N73. 5 Pelvic peritonitis in women, unspecified
- N74. 3 Gonococcal inflammatory diseases of the female pelvic organs (A54. 2 )
- N75 Diseases of the bartholin gland
- O85 Postpartum sepsis
- Z100* CLASS XXII Surgical Practice
- Z98. 8 Other specified post-surgical conditions
Dosage (Posology) and method of administration
V/v, в виде медленной одночасовой инфузии, по 400 мг каждые 12 ч.
The contents of one ampoule (400 mg) are diluted with 250 ml of 5% glucose solution.
Abactal® must not be diluted with a sodium chloride solution or any solvent containing chlorine ions. To quickly achieve an effective concentration in the blood at the beginning of treatment, you can prescribe a shock dose of 800 mg of the drug.
To prevent infections in surgery, it is recommended to administer 400-800 mg of pefloxacin 1 hour before surgery.
In elderly patients, especially with concomitant renal impairment, the dose should be reduced.
In the case of liver disease, 8 mg/kg is prescribed as an infusion for 1 hour:
- 1 time a day (jaundice)
- every 36 hours (ascites)
- every 48 hours (jaundice and ascites).
The maximum daily dose is 1200 mg.
ATC - Anatomical and therapeutic chemical classification
J01MA03 of Pefloxacin