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What is the most important information I should know about Zicam Multi-Symptom Cold and Flu Nighttime?
Hypersensitivity to any of the ingredients.
Paracetamol should not be used in patients with severe liver disease.
Do not use this product if you are being treated with monoamine oxidase inhibitors, or within two weeks of stopping treatment with these medications.
Pseudoephedrine hydrochloride should not be used in patients suffering from any of the following: heart disease (especially coronary insufficiency or arrhythmias), high blood pressure (hypertension), an overactive thyroid gland (hyperthyroidism), tumour of the adrenal gland (phaeochromocytoma), raised intraocular pressure (closed-angle glaucoma) and diabetes mellitus. Pseudoephedrine hydrochloride should be avoided in patients receiving chloroform, cyclopropane, halothane or other halogenated anaesthetics.
Pregnancy and lactation.
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What are the possible side effects of Zicam Multi-Symptom Cold and Flu Nighttime?
Paracetamol may cause pancreatitis, allergic reactions in the form of a rash or blood disorders (including neutropenia, pancytopenia, leucopenia, agranulocytosis and thrombocytopenia). These should disappear on stopping the treatment. The rash usually appears as red areas or allergic wheals, and may be accompanied by fever and involvement of the mucous membranes.
The most common side-effect due to chlorpheniramine is sedation varying from slight drowsiness to deep sleep, including lassitude, dizziness, and inco-ordination. Paradoxical central nervous system stimulation may occur especially in children, with insomnia, nervousness, euphoria, irritability, tremors, and less frequently, nightmares, hallucinations, and convulsions.
Other side effects may include dry mouth; thickened respiratory tract secretions and tightness of the chest, blurred vision, urinary difficulty and retention, constipation and increased gastric reflux. In addition, gastro-intestinal disturbances may occur such as nausea, vomiting, diarrhoea or epigastric pain.
Hypersensitivity reactions may occur. Blood disorders including agranulocytosis, leucopenia, haemolytic anaemia and thrombocytopenia, have been reported. Other less frequently reported side-effects include hypotension, tinnitus, headache and paraesthesias.
Chloropheniramine should be given with care to patients with glaucoma, urinary retention, prostatic hypertrophy or pyloroduodenal obstruction. Caution is advised in patients with epilepsy and severe cardiovascular disorders.
Chlorpheniramine may enhance the sedative effect of central nervous system depressants including alcohol, barbiturates, hypnotic, analgesics, sedatives and tranquillisers. Care should be taken when taking medicines containing tricyclic anti-depressants or atropine together.
Elderly patients are more susceptible to the central nervous system depressant and lowering of blood pressure effects even at dose quantities effective for treatment.
The warning signs of damage caused by ototoxic medicines may be masked by chlorpheniramine.
Other central nervous system depressants, such as alcohol, barbiturates, hyponotics, narcotic analgesics, sedatives and tranquillisers, if taken together will increase the chance of sedation. Be careful when taking medicines containing tricyclic anti-depressants or atropine together.
Pseudoephedrine hydrochloride may cause giddiness, headache, nausea, vomiting, sweating, thirst, rapid or irregular heart beat (tachycardia, ventricular arrhythmia), pain in front of the heart (precordial pain), palpitations, raised blood pressure (hypertension), micturition, difficulty in urination, muscular weakness, tremors, anxiety, restlessness and inability to sleep, fear, confusion, psychotic states, reduced appetite, dyspnoea, sweating, hypersalivation, altered metabolism including disturbance in glucose metabolism. Tolerance with dependence may occur after continued use.
The effects of pseudoephedrine hydrochloride are lessened by medicines containing guanethidine, reserpine, methyldopa and may be diminished or enhanced by tricyclic antidepressants. It may increase the possibility of irregular heart beat in patients taking digitalis.
Pseudoephedrine may increase blood pressure and therefore special care is advisable in patients receiving antihypertensive therapy.
Temporary relief of cough and upper respiratory tract symptoms, including nasal congestion, associated with allergy or common cold.
Acetaminophen (Zicam Multi-Symptom Cold and Flu Nighttime) is a pain reliever and fever reducer.
Dextromethorphan (Zicam Multi-Symptom Cold and Flu Nighttime) is a cough suppressant. It affects the cough reflex in the brain that triggers coughing.
Doxylamine (Zicam Multi-Symptom Cold and Flu Nighttime) is an antihistamine that reduces the effects of the natural chemical histamine in the body. Histamine can produce symptoms of sneezing, itching, watery eyes, and runny nose.
Acetaminophen (Zicam Multi-Symptom Cold and Flu Nighttime), Dextromethorphan (Zicam Multi-Symptom Cold and Flu Nighttime), and Doxylamine (Zicam Multi-Symptom Cold and Flu Nighttime) is a combination medicine used to treat headache, fever, body aches, cough, runny nose, sneezing, and sore throat caused by allergies, the common cold, or the flu.
This medicine will not treat a cough that is caused by smoking, asthma, or emphysema.
Acetaminophen (Zicam Multi-Symptom Cold and Flu Nighttime), Dextromethorphan (Zicam Multi-Symptom Cold and Flu Nighttime), and Doxylamine (Zicam Multi-Symptom Cold and Flu Nighttime) may also be used for purposes not listed in this medication guide.
Use Zicam Multi-Symptom Cold and Flu Nighttime liquid as directed by your doctor. Check the label on the medicine for exact dosing instructions.
Ask your health care provider any questions you may have about how to use Zicam Multi-Symptom Cold and Flu Nighttime liquid.
Zicam Multi-Symptom Cold and Flu Nighttime 1000 mg-30 mg-12.5 mg/30 mL oral liquid:
30 mL orally every 6 hours not to exceed 120 mL daily.
Zicam Multi-Symptom Cold and Flu Nighttime 325 mg-15 mg- 6.25 mg oral capsule:
2 capsules every 6 hours as needed not to exceed 8 capsules/day.
Zicam Multi-Symptom Cold and Flu Nighttime 325 mg-15 mg-6.25 mg/15 mL oral liquid:
30 mL orally every 6 hours not to exceed 120 mL daily.
Usual Adult Dose for Pain
Zicam Multi-Symptom Cold and Flu Nighttime 1000 mg-30 mg-12.5 mg/30 mL oral liquid:
30 mL orally every 6 hours not to exceed 120 mL daily.
Zicam Multi-Symptom Cold and Flu Nighttime 325 mg-15 mg- 6.25 mg oral capsule:
2 capsules every 6 hours as needed not to exceed 8 capsules/day.
Zicam Multi-Symptom Cold and Flu Nighttime 325 mg-15 mg-6.25 mg/15 mL oral liquid:
30 mL orally every 6 hours not to exceed 120 mL daily.
Usual Pediatric Dose for Cough
Acetaminophen (Zicam Multi-Symptom Cold and Flu Nighttime)/Dextromethorphan (Zicam Multi-Symptom Cold and Flu Nighttime) /Doxylamine (Zicam Multi-Symptom Cold and Flu Nighttime) 1000 mg- 30 mg 12.5 mg/30 mL oral liquid:
12 years or older: 30 mL orally every 6 hours not to exceed 120 mL daily.
Zicam Multi-Symptom Cold and Flu Nighttime 325 mg-15 mg- 6.25 mg oral capsule:
12 years or older: 2 capsules every 6 hours as needed not to exceed 8 capsules/day.
Zicam Multi-Symptom Cold and Flu Nighttime 325 mg-15 mg-6.25 mg/15 mL oral liquid:
12 years or older: 30 mL orally every 6 hours not to exceed 120 mL daily.
Usual Pediatric Dose for Pain
Acetaminophen (Zicam Multi-Symptom Cold and Flu Nighttime)/Dextromethorphan (Zicam Multi-Symptom Cold and Flu Nighttime) /Doxylamine (Zicam Multi-Symptom Cold and Flu Nighttime) 1000 mg- 30 mg 12.5 mg/30 mL oral liquid:
12 years or older: 30 mL orally every 6 hours not to exceed 120 mL daily.
Zicam Multi-Symptom Cold and Flu Nighttime 325 mg-15 mg- 6.25 mg oral capsule:
12 years or older: 2 capsules every 6 hours as needed not to exceed 8 capsules/day.
Zicam Multi-Symptom Cold and Flu Nighttime 325 mg-15 mg-6.25 mg/15 mL oral liquid:
12 years or older: 30 mL orally every 6 hours not to exceed 120 mL daily.
Renal Dose Adjustments
Data not available
Liver Dose Adjustments
Data not available
Dialysis
Data not available
