Zest-m

Contraindications

do not use in the treatment of leber disease or tobaco intoxication.

Undesirable effects

anaphylactic reactions rarely, severe cases can cause death, urine yellow colouration,peripheral neuropathy in case of prolonged useage, arrythmias,

Therapeutic indications

An indication is a term used for the list of condition or symptom or illness for which the medicine is prescribed or used by the patient. For example, acetaminophen or paracetamol is used for fever by the patient, or the doctor prescribes it for a headache or body pains. Now fever, headache and body pains are the indications of paracetamol. A patient should be aware of the indications of medications used for common conditions because they can be taken over the counter in the pharmacy meaning without prescription by the Physician.

Pernicious anaemia, peripheral neuritis especially diabetic and alcoholic polyneuritis, trigeminal neuritis, vomiting of pregnancy, vitamin B complex deficiency, anorexia, agranulocytosis, radiation sickness, coeliac and idiopathic, steatorrhoea which are usually accompanied by malabsorption of vitamin B 12 and during administration of broad-spectrum antibiotics.

Name of the medicinal product

Zest-M

Qualitative and quantitative composition

Zest-M (rINN, or S-benzoylthiamine O-monophoshate) is a synthetic S-acyl derivative of thiamine (vitamine B1). After absorption, Zest-M can be dephosphorylated by cells bearing an ecto-alkaline phosphatase to the lipid-soluble S-benzoylthiamine. Zest-M should not be confused with allithiamine, a naturally occurring thiamine disulfide derivative with a distinct pharmacological profile.

Special warnings and precautions for use

There are specific as well as general uses of a drug or medicine. A medicine can be used to prevent a disease, treat a disease over a period or cure a disease. It can also be used to treat the particular symptom of the disease. The drug use depends on the form the patient takes it. It may be more useful in injection form or sometimes in tablet form. The drug can be used for a single troubling symptom or a life-threatening condition. While some medications can be stopped after few days, some drugs need to be continued for prolonged period to get the benefit from it.

Beri Beri, Wenicke-korsakoff syndrome. diabetic neuropathy.

Dosage (Posology) and method of administration

Oral

Alcoholic neuropathy; Diabetic neuropathy

Adult: 100 mg 4 times daily.

Interaction with other medicinal products and other forms of interaction

none known