Otolone

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Otolone Medicine

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Contraindications

"Adults (including the Elderly) and Children

One to two drops applied topically to each affected eye up to six times daily or more frequently if required. (Severe infections may require one to two drops every fifteen to twenty minutes initially, reducing the frequency of instillation gradually as the infection is controlled)."

Undesirable effects

Local

Sensitivity reactions such as transient irritation, burning, stinging, itching and dermatitis, may occasionally occur.

Systemic

Rarely, cases of major adverse haematological events (bone marrow depression, aplastic anaemia and death) have been reported following ocular use of Chloramphenicol (Otolone).

Therapeutic indications

An indication is a term used for the list of condition or symptom or illness for which the medicine is prescribed or used by the patient. For example, acetaminophen or paracetamol is used for fever by the patient, or the doctor prescribes it for a headache or body pains. Now fever, headache and body pains are the indications of paracetamol. A patient should be aware of the indications of medications used for common conditions because they can be taken over the counter in the pharmacy meaning without prescription by the Physician.

Acne urticata, Candidiasis, Dermatitis, atopic

Dermatitis, contact, Dermatitis, infectious

Dermatitis stasis, Eczema

Folliculitis, Intertrigo, Lichen simplex chronicus, Pruritus, anogenital

Pyoderma, Tinea capitis, Tinea corporis

Tinea cruris, Tinea pedis

Name of the medicinal product

Otolone

Qualitative and quantitative composition

An antibiotic first isolated from cultures of Streptomyces venequelae in 1947 but now produced synthetically. It has a relatively simple structure and was the first broad-spectrum antibiotic to be discovered. It acts by interfering with bacterial protein synthesis and is mainly bacteriostatic. (From Martindale, The Extra Pharmacopoeia, 29th ed, p106)

Dosage (Posology) and method of administration

Instill 2 drops 1-3 times daily.

Interaction with other medicinal products and other forms of interaction

Chymotrypsin will be inhibited if given simultaneously with Chloramphenicol (Otolone).