Symptoms : psychomotor arousal, irritability, drowsiness, urination delay, tremor, tachycardia, itching, rash.
Treatment: gastric lavage, activated carbon, laxatives, symptomatic therapy.
Hypersensitivity to the components of the drug and to hydroxysine.
Theophylline reduces Cl and increases the plasma concentration of the drug.
From the cardiovascular system and blood (blood-breeding, hemostasis) : hemolytic anemia, thrombocytopenia.
From the side of the LCD : nausea, vomiting, abdominal pain, diarrhea, constipation, increased appetite, transient increase in liver transaminase activity.
From the side of the nervous system and the senses : drowsiness, a sense of fatigue, weakness, dizziness, headache, dry mouth.
Seasonal and year-round allergic rhinitis, allergic conjunctivitis, chronic urticaria, Quinke edema, etc. allergic diseases.
The action manifests itself after 20 minutes, reaches a maximum after 1 h and continues for 24 hours.
Quickly absorbed from the LCD (70%), Cmax achieved after 1 h. It is slightly metabolized in the liver, excreted with urine mainly unchanged.
Keep out of the reach of children.
Shelf life of the drug Letisen®5 years.Do not apply after the expiration date indicated on the package.
1 tablet coated with a film shell contains 10 mg dichloride cetrinis; in the contour cell package 10 pcs., in a cardboard pack of 1 or 2 packs.
It should not be taken in the I trimester of pregnancy, in II-III it is possible by strict indications. Breastfeeding should be stopped during treatment.
Inside, before or after eating, drinking with a small amount of liquid, for adults and children over 12 years old - 10 mg / day, for children 6-12 years old (body weight more than 30 kg) - 5 mg 2 times a day, for children 6-12 years old (body weight less than 30 kg) - 5 mg / day.
Against the background of renal failure (Cl creatinine 11–13 ml / min), hemodialysis (Cl creatinine less than 7 ml / min) or impaired liver function - 5 mg / day.
