Home / Medicine / Helicid
How does this drug class actually work?
Read the plain-language explainer in Pharmacology Academy (Proton pump inhibitors) →

Incompatibilities

Not applicable.

Preclinical safety data

Gastric ECL-cell hyperplasia and carcinoids have been observed in life-long studies in rats treated with Helicid. These changes are the result of sustained hypergastrinaemia secondary to acid inhibition. Similar findings have been made after treatment with H2-receptor antagonists, proton pump inhibitors and after partial fundectomy. Thus, these changes are not from a direct effect of any individual active substance.

Special precautions for disposal and other handling

No special requirements for disposal.