Symptoms: increased dose-dependent side effects.
Treatment: the drug should be discontinued, the damaged area should be washed, and the drug should be removed.
hypersensitivity to the drug Dimexide or other components of the drug,
severe liver and kidney damage,
angina pectoris,
myocardial infarction,
severe atherosclerosis,
different types of stroke,
glaucoma, cataract,
coma,
pregnancy,
lactation period,
children under 12 years of age.
Due to the fact that the drug Dimexide can increase not only the activity, but also the toxicity of some drugs, care should be taken when prescribing it simultaneously with other drugs.
Compatible with heparin, antibacterial drugs, NSAIDs.
Increases the sensitivity of microorganisms to aminoglycoside and beta-lactam antibiotics, chloramphenicol, rifampicin, griseofulvin.
Colorless or yellowish transparent gel with a faint specific smell.
During the use of the drug, contact dermatitis, garlic smell of exhaled air, increased skin pigmentation, allergic reactions, erythematous rashes, dry skin, light burning may occur. Some patients do not perceive the smell of the drug well (nausea, vomiting), in isolated cases, bronchospasm is possible. If any of the side effects listed in the description have worsened or any other side effects not listed in the description have occurred, you should inform your doctor.
Without a prescription.
Given the possibility of individual intolerance to the drug, it is recommended to conduct a drug test for tolerance to it. To do this, a thin layer of gel is applied to the skin of the elbow fold. The appearance of sharp redness and itching indicates an increased sensitivity to the drug Dimexide.
If allergic reactions occur during treatment with the drug, the use of the drug is discontinued, H blockers are prescribed.1- histamine receptors.
It is used to relieve pain in the complex therapy of the following diseases and conditions:
rheumatoid arthritis,
Bekhterev's disease,
deforming osteoarthritis,
arthropathy,
sciatica,
trigeminal neuralgia, etc.,
for the treatment of bruises,
ligament damage,
traumatic infiltrates,
in the treatment of erythema nodosum.
Anti-inflammatory agent that has a local analgesic and anti-inflammatory effect. It has a moderate antiseptic and fibrinolytic effect.
Dimethyl sulfoxide inhibits inflammatory tissue infiltration. In addition, dimethylsulfoxide contributes to the normalization of fibrin formation processes, increases microcirculation in tissues, inhibits the aggregation of red blood cells, increases the activity of phagocytes, suppresses neutrophil chemotaxis and reduces the content of circulating immune complexes.
Penetrates through the skin, mucous membranes, the cell wall of bacteria (increases their sensitivity to antibiotics) and other biological membranes, increases their permeability to drugs. The drug is low-toxic.
When applying the drug, dimethylsulfoxide is detected in the blood serum after 8-15 minutes, with the maximum content noted after 2-8 hours. As a rule, after 30-36 hours, dimethyl sulfoxide in the blood serum is no longer detected. Dimethylsulfoxide does not accumulate. With topical application of the drug, dimethylsulfoxide penetrates into the joint cavity, binds to proteins in the blood and tissues.
Dimethylsulfoxide is excreted from the body through the kidneys unchanged and in the form of oxidation products — dimethylsulfone and dimethylsulfate, as well as in the form of a reduced product (dimethylsulfide) is released with exhaled air.
At a temperature not exceeding 25 °C.
Keep out of reach of children.
Shelf life of the drug Dimexide2 года.Do not use after the expiration date indicated on the package.
| Gel for external use | 100 g |
| active substance: | |
| dimexide (dimethyl sulfoxide) | 25 g |
| excipients: methyl parahydroxybenzoate (nipagin) - 0.05 g, propyl parahydroxybenzoate (nipazole) - 0.013 g, carmellose sodium (sodium carboxymethylcellulose) - 2 g, purified water-up to 100 g |
Gel for external use, 25%. In aluminum or plastic tubes according to 20, 30, 50, 100, 150, 200, 250 or 500 g in a jar with a lid made of HDPE or in a bottle with a lid made of HDPE. Each tube is placed in a cardboard box.
From 5 to 20 cans or vials in a cardboard box (for hospitals).
Externally. Adults and children over 12 years of age, the drug is applied in a thin layer to the affected area 1-2 times a day. The duration of treatment is 10-14 days. Repeated courses can be conducted in at least 10 days.
M02AX03 Dimethyl Sulfoxide
