Symptoms: nausea, vomiting, thirst, constipation, chronic vitamin D overdose3 it is possible to develop calcification of blood vessels and tissues.
Treatment: cancellation of the drug, you need to consult a doctor.
Hypersensitivity, hypercalcemia, hypercalciuria, urolithiasis (formation of calcium stones), osteoporosis due to prolonged immobilization.
With caution - for kidney failure and sarcoidosis.
Hypersensitivity, hypervitaminosis D, severe renal impairment, hypercalcemia, hypercalciuria, urolithiasis (formation of calcium stones), decalcifying tumors (myeloma, bone metastases, sarcoidosis), osteoporosis due to immobilization, pulmonary tuberculosis (active form), children under 12 years of age.
When used concomitantly with vitamin A, the toxicity of vitamin D is reduced. Phenytoin, barbiturates, glucocorticoids reduce the effectiveness of vitamin D3. Glucocorticoids reduce the absorption of calcium. Colestyramine, laxatives (paraffin oil) reduce the absorption of vitamin D3. With the simultaneous use of tetracyclines, the interval between doses should be at least 3 hours, bisphosphonates and sodium fluoride (their absorption is disturbed) - at least 2 hours — When combined with cardiac glycosides, their toxicity increases (ECG and clinical condition monitoring is necessary), with thiazide diuretics, the risk of hypercalcemia increases, with furosemide and other "loop" diuretics, the excretion of calcium by the kidneys increases.
From the gastrointestinal tract: constipation or diarrhea, flatulence, pain in the epigastric region, nausea.
From the side of metabolism: in rare cases, with prolonged use in high doses — hypercalcemia, hypercalciuria.
Other: allergic reactions.
Allergic reactions, gastrointestinal dysfunction (constipation, diarrhea, flatulence, nausea, abdominal pain), with prolonged use, hypercalcemia and hypercalciuria are possible.
Vitamin D3 increases the absorption of calcium in the gastrointestinal tract and its binding in the bone tissue. Prevents an increase in the production of parathyroid hormone, which is a stimulator of bone resorption.
Inside, tablets should be absorbed or chewed. The average daily dose is 2 tablets (1 tablet each). in the morning and in the evening, unless otherwise prescribed by the doctor). The course is based on the doctor's recommendation.
Inside, while eating.
As a preventive measure, adults and children over 12 years of age, pregnant and lactating women-1-2 tablets. in the day.
The exchange rate for the prevention of osteoporosis — 2 table. per day (morning and evening)
For the treatment of osteoporosis-the course and dosage in accordance with the doctor's recommendations.
