Symptoms: "goose" skin, especially in the area of the head (back of the head) and neck, a feeling of cold, delayed urination, urge to urinate (as a result), possibly (reflex) slowing of the heart rate (at rest below 60 beats per minute).
Treatment: the use of atropine in normal doses.
Hypertension, angle-closure glaucoma, pheochromocytoma, hyperthyroidism, acute nephritis, severe renal failure,mechanical obstruction of the urinary tract, prostate adenoma with residual urine.
Violation of the heart rhythm, the appearance of pain in the heart, allergic reactions (rash).
Hypotension (caused by taking psychotropic drugs, symptomatic in the period of convalescence after surgery, childbirth, etc.), orthostatic hypotension (with disorders of the regulation of blood circulation and circulatory dysregulations, with reactions such as sympathicotonia and asympathicotonia, idiopathic, secondary), hypotonic reactions (with changes in the weather, morning, with a predisposition to low blood pressure), spontaneous urination (with disorders of the sphincter function of the bladder).
Increases the tone and peripheral resistance of arterial vessels, increases blood pressure and prevents (in orthostatic disorders) stagnation of blood in the venous bed. This leads to the maintenance of a constant level of the volume of circulating blood and blood pressure, an increase in blood delivery to the organs and the elimination of orthostatic disorders. It does not directly affect the activity of the heart, the central nervous system (does not cause sleep disorders). Improves the function of the bladder sphincter.
When used orally, it is rapidly absorbed, becoming an active metabolite. After intravenous injection, the effect develops relatively slowly and persists for a long time. T1/2 the active metabolite in the plasma is 3-4 hours. Due to the very low lipophilicity, it practically does not penetrate through the BBB. Midodrin and its metabolites are excreted in the urine almost completely within 24 hours.
Bramox
Midodrine
Pills: adults, children of adolescent age (12 years and older) — inside, 2.5 mg 2 times a day (morning and evening), if necessary — 3 times a day, in some cases, the dosage can be reduced to 2 times 1/2 table. per day (2.5 mg), with simultaneous administration with sedatives or hypnotics, first take 2.5 mg 2 times a day, then (if necessary) the dose is increased to 5 mg 2-3 times a day, for children under 12 years of age — the dose is calculated depending on body weight.
Drops: adults, children over 12 years of age — inside, 7 drops 2 times a day (morning and evening), if necessary, the dose is reduced to 3 drops 2 times a day or in rare cases increased to 7 drops 3 times a day, in combination with psychotropic drugs — 7 drops 2 times a day or (if necessary) 15 drops 2-3 times a day, children under 12 years of age are dosed depending on body weight.
Drops should be taken with a small amount of water or on a piece of sugar.
