Biotredin

Overdose

Not identified.

Contraindications

hypersensitivity to vitamin B6,

state of alcoholic intoxication,

simultaneous administration of anxiolytics, neuroleptics, and antidepressants.

Incompatibilities

Incompatible with antipsychotic drugs, antidepressants, anxiolytics, barbiturates.

Weakens the effect of other drugs that depress the central nervous system.

Pharmaceutical form

Tablets are white or white with a slightly yellowish tinge of color of a flat-cylindrical shape with a chamfer.

Undesirable effects

Dizziness, increased sweating, allergic reactions with vitamin B intolerance6.

Pharmacy sales terms

Without a prescription.

Special instructions

It is not recommended to use in a state of intoxication (because the therapeutic effect of the drug is reduced).

Therapeutic indications

reduced mental performance and concentration in adults, adolescents and children,

alcohol abuse and chronic alcoholism, with a pathological attraction to alcohol, accompanied by affective (irritability, decreased mood, internal discomfort), sensory (hunger) and ideatory (thoughts about alcohol) disorders,

alcohol withdrawal syndrome and for the maintenance of remission in alcoholism.

Pharmacotherapeutic group

  • B vitamins other preparations [Vitamins and vitamin-like agents in combinations]
  • Vitamins of group B other preparations [Means for correction of violations at alcoholism, toxico-and drug addiction in combinations]

Pharmacodynamic properties

Biotredin® it is a regulator of tissue metabolism, increases mental performance, has a therapeutic effect in alcohol withdrawal, reduces the desire for alcohol.

L-threonine in the presence of pyridoxine (vitamin B6) breaks down to form the amino acids glycine and acetaldehyde, which stimulate the processes of inhibition and at the same time redox reactions, respiration and ATP synthesis in cells, due to which the drug is able to:

- reduce psychoemotional stress,

- improve short-term and long-term memory,

- improve mental performance,

- normalize the level of endogenous acetaldehyde and thereby reduce the manifestations of alcohol withdrawal syndrome and craving for alcohol.

The effect of the drug Biotredin® it manifests itself in 10-20 minutes after sublingual administration.

Pharmacokinetic properties

L-threonine and vitamin B6 completely metabolized to the final products. Their accumulation in the body does not occur.

Special precautions for storage

In a dry place, protected from light, at a temperature not exceeding 25 °C.

Keep out of reach of children.

Shelf life of the drug Biotredin®3 года.

Do not use after the expiration date indicated on the package.

Nature and contents of container

Sublingual tablets 1 table.
active ingredients:  
L-Threonine 100 mg
pyridoxine hydrochloride 5 mg
excipients: Low molecular weight PVP (povidone) — 4 mg, citric acid, monohydrate-6.83 mg, magnesium stearate-1.17 mg  
Release form

Sublingual tablets, 5 mg 100 mg. According to 30 tables. in a contour cell package, in a pack of cardboard 1 package.

Fertility, pregnancy and lactation

No special studies were conducted. It is not recommended for use during pregnancy and lactation. In case of alcohol abuse and alcoholism, the drug can be used during pregnancy and during breastfeeding.

Nosological classification (ICD-10)

  • F10. 1 Harmful use of alcohol
  • F10. 2 Alcohol dependence syndrome
  • F10. 3 Withdrawal status
  • F34. 8 Other persistent mood disorders [affective]
  • F48 Other neurotic disorders
  • F60. 3 Emotionally unstable personality disorder
  • F90. 0 Disturbance of activity and attention
  • R41. 8. 0* Intellectual-mnestic disorders
  • R45. 4 Irritability and anger

Dosage (Posology) and method of administration

Sublingual in the form of a tablet or powder after grinding the tablet.

To increase attention and mental performance: children, adolescents and adults: 1 table 2-3 times a day for 3-10 days. If necessary, the course is repeated 3-4 times or more a year.

For the treatment of chronic alcoholism and alcohol abuse: 1-3 tablets 2-3 times a day for 4-5 days. If necessary, the course is repeated up to 5-10 times a year.

For the treatment of alcohol withdrawal syndrome: on the first day-1-4 tablets 3-4 times a day (daily dose-3-16 tablets), then-1-2 tablets 2-3 times a day (daily dose-3-6 tablets) for 21-28 days. The course can be reduced to 10-14 days.

The greatest effect of the drug Biotredin® it is achieved when combined with glycine-1 table (100 mg) sublingually 10-15 minutes before taking the drug Biotredin®.

In the period of remission for revealing latent craving for alcohol: take 2-3 tablets of the drug Biotredin® on an empty stomach. The appearance within 10-20 minutes of light dizziness, a calming effect, redness of the face, sweating indicate the presence of a hidden attraction. In these cases, a 5-10-day course of taking the drug Biotredin is recommended® 1-2 tablets 2-3 times a day (in combination with glycine, 100 mg sublingually for 10-15 minutes before taking the drug Biotredin®).

ATC - Anatomical and therapeutic chemical classification

A11JC Vitamins in combination with other drugs