Prolonged or too frequent administration of the drug in young children can lead to central nervous system inhibition, hypothermia, coma, prolonged pupil dilation. Naphazoline can cause a sudden decrease in blood pressure and tachycardia.
There are no data concerning acute overdose of drops injected topically into the conjunctival sac.
Hypersensitivity to the components of the drug and adrenomimetic agents, narrow-angle glaucoma.
The use of drugs containing naphazoline in patients treated with tricyclic antidepressants may increase its vasoconstrictive effect. Concomitant use of MAO inhibitors with naphazoline may lead to a hypertensive crisis.
Most often-temporary symptoms from the conjunctiva: burning, itching, ophthalmalgia, vision disorder, redness of the conjunctiva, possibly-dilation of the pupil or an increase in intraocular pressure. A case of corneal opacification in a patient who instilled the drug in the conjunctival sac for 7 days at least 10 times a day is described. After discontinuation of the drug, the opacity disappeared.
Very rarely — drowsiness, palpitations, high blood pressure, headache, dizziness, nausea.
The appearance of any general reactions or prolonged local irritation requires discontinuation of the drug.
Acute, seasonal or year-round allergic conjunctivitis, irritation of the conjunctiva during the use of contact lenses, from exposure to sunlight, cigarette smoke, contact with water in a swimming pool, etc.
The full local effect of naphazoline is detected after 5 minutes from the moment of topical application of the drug. Its action lasts up to 8 hours, and with frequent use of a large amount-up to 6 hours.
Naphazoline can be absorbed from the mucous membranes, causing general symptoms, although such an effect in adults after administration of the drug in the conjunctival sac is unlikely. General reactions mainly occur in elderly patients and in young children.
In a place protected from light, at a temperature of 15-25 °C.
Keep out of reach of children.
The shelf life of the drug Deladrin®3 года. После вскрытия — 4 нед.Do not use after the expiration date indicated on the package.
| Eye drops | 1 ml |
| diphenhydramine hydrochloride | 1 mg |
| of naphazoline nitrate | 0.33 mg |
| excipients: benzalkonium chloride 50%, disodium salt of ethylenediaminetetraacetic acid, boric acid, water up to 1 ml |
in bottles of 5 ml, in a box of 1 or 2 bottles.
During pregnancy, the drug can be used only if, in the opinion of the doctor, the benefit to the mother prevails over the potential danger to the fetus.
Conjunctival, adults and children over 2 years — 1-2 drops, but not more often than every 6-8 hours.
The drug should not be used for more than 3-5 days without the consent of an ophthalmologist.
S01GA51 Naphazoline in combination with other drugs
