Benoxi

Overdose

There are no data on drug overdose.

Contraindications

Individual hypersensitivity to the components of the drug.

Incompatibilities

The literature does not describe the negative or positive effects of simultaneous administration of oxybuprocaine and other traditionally used eye drops into the conjunctival cavity.

It is noted that oxybuprocaine can theoretically reduce the antibacterial activity of sulfonamides.

Pharmaceutical form

Eye drops

Undesirable effects

Short-term tingling sensation, burning and hyperemia of the conjunctiva, allergic reactions, keratitis (rarely).

Therapeutic indications

Local anesthesia in ophthalmology:

measurement of intraocular pressure (tonometry),

gonioscopy,

diagnostic scraping of the conjunctiva,

extraction of foreign bodies and sutures from the cornea and conjunctiva,

short-term surgical interventions on the cornea and conjunctiva.

Pharmacotherapeutic group

  • Local anesthetics
  • Ophthalmic products

Pharmacodynamic properties

A local anesthetic that blocks nerve endings. It penetrates well into the tissues when applied topically. Compared to tetracaine and other local anesthetics, it has a less irritating effect on the conjunctiva and cornea.

Surface anesthesia of the conjunctiva and cornea occurs after 30 seconds and lasts for 15 minutes.

Pharmacokinetic properties

Benoxi easily penetrates the corneal stroma after a single instillation into the conjunctival cavity. During the next 15 minutes, there is a quantitative decrease in the stromal concentration of the drug, which causes a 12-15-minute period of anesthesia with a single instillation.

Qualitative and quantitative composition

Oxybuprocaine

Dosage (Posology) and method of administration

Local, instill in the conjunctival sac 1 drop at a time. Long-term anesthesia (up to 1 h) is provided by three-time instillation of Vepohiya with an interval of 4-5 minutes.

ATC - Anatomical and therapeutic chemical classification

S01HA02 the Oxybuprocaine