Papaverine hydrochloride

Overdose

No information provided.

Contraindications

Large doses can depress atrioventricular and intraventricular conduction and thereby produce serious arrhythmias.

Pharmaceutical form

Injection; Pills; Rectal suppositories; Substance; Substance-powder

Undesirable effects

Although occurring rarely, the reported side effects of Papaverine Hydrochloridee include nausea, abdominal distress, anorexia, constipation, malaise, drowsiness, vertigo, sweating, headache, diarrhea, skin rash, flushing of face, increase in heart rate and depth of respiration and slight increase in blood pressure.

Therapeutic indications

For the relief of cerebral and peripheral ischemia associated with arterial spasm and myocardial ischemia complicated by arrhythmias.

Special warnings and precautions for use

WARNINGS

No information provided.

PRECAUTIONS

Use with caution in patients with glaucoma. Hepatic hypersensitivity has been reported with gastrointestinal symptoms, jaundice, eosinophilia and altered liver function tests. Discontinue drug if these occur.

Dosage (Posology) and method of administration

One capsule every 12 hours. In difficult cases administration may be increased to one capsule every 8 hours or two capsules every 12 hours.