натрия цитрата пентасесквигидрат

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натрия цитрата пентасесквигидрат Medicine

Overdose

Симптомы: для пациентов, не имеющих нарушений функции почек, обычно не существует риска отравления или передозировки данным препаратом. При применении данного глюкозо-электролитного раствора у пациентов с подтвержденным или латентно протекающим сахарным диабетом (diabetes mellitus) может увеличиться уровень сахара в крови вплоть до состояния диабетической комы. Случайная интоксикация неразбавленным порошком может нарушить электролитный баланс и усилить диарею.

Всегда следует консультироваться с врачом в случае передозировки.

Contraindications

Hypersensitivity (including.h. to citrates), increased bleeding due to a violation of the coagulation system.

Incompatibilities

The effect of heart glycosides can be weakened. In patients undergoing glycosides treatment, when taking Hydrovite® it is necessary to control the concentration of potassium in the blood.

Undesirable effects

Nausea, chills, rashes.

Therapeutic indications

Hemoconservation (collection and storage of whole blood - TsFD, long-term storage of red blood cells - Adsol).

Pharmacotherapeutic group

  • Regulators of water-electrolyte balance and KSHS
  • Anticoagulants

Pharmacodynamic properties

The CFG solution provides an anticoagulant effect by binding calcium cations with citrate anions, in addition, the glucose contained in the drug serves as a nutrition for blood cells, and phosphate supports the buffer blood system.

The hemoconservative solution is mixed with blood in the ratio of 1 volume to 7 blood volumes.

Pharmacokinetic properties

After oral use, glucose undergoes metabolism to carbon dioxide and water (CO2 and N2Oh), and the rest of the components are derived mainly with urine and only in small quantities - with sweat or feces.

Qualitative and quantitative composition

Adenine Citric Acid; Dextrose; Mannitol; Sodium Chloride; Sodium Citrate; Sodium Dihydrophosphate

Dosage (Posology) and method of administration

At 100 ml of blood - 8–10 ml of hemoconservant solution. Whole blood in the solution of this coagulant is stored at a temperature of 1–6 ° C for 21 days from the date of the fence.