Acute overdose of local use of Abzorb is unlikely and does not lead to a life-threatening situation.
Hypersitivity, pregnancy (I trimester).
known hypersensitivity to the active substance of the drug or to any of the above auxiliary ingredients that is part of it (see. section "Composition");
I trimester of pregnancy.
Amphotericin B, nystatin, natamicin lower the efficiency of clotrimazole with simultaneous use.
Canison® vaginal tablets 100 mg reduces the effect of polyenic antifungal antibiotics (amphotericin, nystatin, natamycin, etc.).
Perhaps a feeling of burning, tingling at the place of application of cream, the appearance of erythema, blisters, swelling, irritation and peeling of the skin, allergic reactions (zud, urticaria).
The drug is Canison® vaginal tablets of 100 mg usually do not irritate the vaginal mucosa. The drug is not subject to resorption and does not have a general effect. Extremely rare is increased sensitivity to the drug.
Fungal lesions of the skin and mucous membranes: dermatomycosis, dermatophytia, trichophytia, epidermophytia, microsporia, candidomycosis; inter-finger fungal erosion, fungal paronichia; candid balanitis; choppy lichen; eritrazism; mycosis complicated by secondary pyodermia.
candidiasis vulvovaginitis ;
colpitis and other superinfections (including mixed ones) caused by microorganisms sensitive to the drug Canison®.
The antifungal effect of the drug is associated with a violation of the synthesis of ergosterin and the cell membrane of the fungus. It has a wide range of activities. Fungistatic or fungicide activity depends on the type of microorganisms.
The drug is effective for yeast-like mushrooms, first of all Candida spp. (Candida albicans, Candida tropicalis, Candida pseudotropicalis, Candida krusei, Candida parapsilosis, etc.), Torulopsis spp., Rhodotorula spp. and mold mushrooms (Aspergillus spp.).
Canison® vaginal tablets 100 mg has an effect on gram-positive bacteria : Streptococcus spp. (e.g Streptococcus pyogenes) and Staphylococcus spp. (e.g Staphylococcus aureus) and gram-negative bacteria (Bacteroides spp. and Haemophilus vaginalis).
With intravaginal administration, the drug has only local effect, the minimum amount is absorbed through the vaginal mucosa.
Outwardly and locally. The cream is applied in a thin layer to the affected areas of the skin and mucous 2-3 times a day and carefully rub. A one-time dose on the surface area the size of a palm is a column of a cream 5 mm long. The course of treatment on average is about 4 weeks, but upon its completion (the disappearance of clinical manifestations) it is advisable to continue the use of the drug for another 14 days. The duration of erythrazma therapy is 2–4 weeks, multi-colored lichen is 1–3 weeks.
Before lubricating, the feet are washed with warm water and soap, carefully wiped, especially between the fingers. With fungal lesions of the skin of the legs after achieving the therapeutic effect, it is recommended to continue treatment for 2-3 weeks.
Intravaginal once a day (preferably in the evening) for 6 days. If necessary, the course of treatment can be repeated. The duration of treatment is usually 6 days.
In the presence of candidiasis vulvit or candidiasis balanite, it is recommended to simultaneously appoint Canison® 1% cream, applying it externally (2-3 times a day for 6-12 days) to affected areas.
The use of vaginal tablets using a vaginal applicator :
the vaginal tablet is removed from the package and is inserted into the vaginal applicator; the vaginal applicator with the vaginal tablet is inserted deep into the vagina, and its piston is neatly promoted to the end (thus the vaginal tablet will enter the vagina); after using the vaginal applicator is thoroughly washed with warm water. It is not recommended to wash the vaginal applicator with boiling water!
