клотримазол-акрихин

клотримазол-акрихин Medicine

Overdose

Acute overdose of local use of Abzorb is unlikely and does not lead to a life-threatening situation.

Contraindications

Hypersensitivity, pregnancy (I trimester).

Incompatibilities

Reduces the effects of polyenic antibiotics (amphotericin, nystatin, natamycin, etc.). The saw ether of paragydroxybenzoyic acid in high concentrations enhances the antifungal effect of clotrimazole, dexamethasone reduces.

Pharmaceutical form

Cream

Undesirable effects

Rarely - urticaria, swelling, rash, erythema, burning, itching, irritation at the place of application of the drug.

Therapeutic indications

Fungal lesions of the skin and mucous membranes. Mycoses of feet / brushes, smooth skin of the body, limbs, folds, areas of the beard, mustache, scalp caused by dermatophytes. Chopped lichen, erythrasma, skin candidiasis, genital mucosa, paronichia.

Pharmacotherapeutic group

  • Anti-fungal means
  • Other synthetic antibacterial agents

Pharmacodynamic properties

Active in relation to dermatophytes, yeast-like and mold mushrooms, as well as the causative agent of multi-colored lichen (Pityriasis versicolor) and the causative agent of eritrazma. It has an antimicrobial effect on gram-positive (Staphylococcus, Streptococcus) and gram-negative bacteria (Bacteroides, Gardnerella vaginalis), as well as on Trichomonas vaginalis.

Pharmacokinetic properties

It accumulates in the horn layer of the epidermis (the concentration of the drug in the lower layers of the epidermis is significantly higher than the minimum overwhelming concentration established in vitro for dermatophytes), when applied to the nails, is found in keratin. For external use, it is practically not absorbed into the systemic blood flow through the skin, and to a small extent absorbed from the mucous membranes.

Special precautions for storage

At a temperature not higher than 25 ° C .

Keep out of the reach of children.

Shelf life of the drug Klotrimazol-Akrikhin3 years.

Do not apply after the expiration date indicated on the package.

Nature and contents of container

Solution for external use 1% 1 ml
clotrimazole 10 mg

in dark glass bottles of 15 ml complete with a dropper; in a cardboard pack 1 set.

Fertility, pregnancy and lactation

It is shown in the I trimester of pregnancy, in the II and III trimesters and when breastfeeding, it is possible if the expected effect of therapy exceeds the potential risk for the fetus or newborn. Applying the drug directly to the mammary gland during breastfeeding is not recommended.

Qualitative and quantitative composition

Clotrimazol

Dosage (Posology) and method of administration

Locally. Adults and children are applied a few drops of the solution with a thin layer on the purified and dry affected and surrounding areas of the skin 2 times a day (morning and evening) and carefully rub. After eliminating the acute symptoms of the disease, treatment of up to 4 weeks should be continued, with dermatomycosis of the feet - within 2 weeks after eliminating all the symptoms.

ATC - Anatomical and therapeutic chemical classification

D01AC01 Clotrimazole