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What is the most important information I should know about Expectum?
Salbutamol (Expectum)-Guaifenesin (Expectum) (Expectum) should not be used in patients with history of hypersensitivity to Salbutamol (Expectum) or Guaifenesin (Expectum).
Salbutamol (Expectum) should be avoided during the first and second trimesters of pregnancy.
Salbutamol (Expectum) should not be administered concomitantly with other sympathomimetic agents as it may cause adverse effects on the cardiovascular system.
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What are the possible side effects of Expectum?
As the combination product contains Salbutamol (Expectum) and Guaifenesin (Expectum), the type and severity of adverse reactions associated with each of the components may be expected. The adverse reaction profile is derived from the individual components since there are limited clinical and post-marketing reports available for the combination product.
Adverse reactions are listed as follows by system organ class and frequency. Frequencies are defined as: Very common (≥1/10), common (≥1/100 to <1/10), uncommon (≥1/1,000 to <1/100), rare (≥1/10,000 to <1/1,000) and very rare (<1/10,000) including isolated reports. Very common and common reactions were generally determined from clinical trial data. Rare and very rare reactions were generally determined from spontaneous data.
Salbutamol (Expectum): Immune System Disorders: Very Rare: Hypersensitivity reactions including angioedema, urticaria, bronchospasm, hypotension and collapse.
Metabolism and Nutrition Disorders: Rare: Hypokalemia.
Potentially serious hypokalemia may result from β2-agonist therapy.
Nervous System Disorders: Very Common: Tremor. Common: Headache. Very Rare: Hyperactivity.
Cardiac Disorders: Common: Tachycardia, palpitations. Rare: Cardiac arrhythmias including atrial fibrillation, supraventricular tachycardia and extrasystoles.
Vascular Disorders: Rare: Peripheral vasodilatation.
Musculoskeletal and Connective Tissue Disorders: Common: Muscle cramps. Very Rare: Feeling of muscle tension.
Guaifenesin (Expectum): Immune System Disorders: Unknown: Hypersensitivity and allergic reactions including anaphylactic reactions, angioedema, rash, urticaria and dyspnea.
Gastrointestinal Disorders: Unknown: Nausea, vomiting, abdominal discomfort.
Salbutamol (Expectum) is a selective β2-adrenoceptor agonist indicated for the treatment or prevention of bronchospasm. It provides short-acting (4 hrs) bronchodilation in reversible airways obstruction due to asthma, chronic bronchitis and emphysema.
Bronchodilators should not be the only or main treatment in patients with persistent asthma. In patients with persistent asthma unresponsive to Salbutamol (Expectum), treatment with inhaled corticosteroids is recommended to achieve and maintain control. Failing to respond to treatment with Salbutamol (Expectum) may signal a need for urgent medical advice or treatment.
The combination of Salbutamol (Expectum) with Guaifenesin (Expectum) is designed to relieve respiratory obstruction and improve pulmonary ventilation. Respiratory disorders where bronchospasm and excessive secretion of tenacious mucus are complicating factors, eg, bronchial asthma, chronic bronchitis and emphysema.
Dexbrompheniramine is an antihistamine that reduces the effects of natural chemical histamine in the body. Histamine can produce symptoms of sneezing, itching, watery eyes, and runny nose.
Dexbrompheniramine is used to treat runny nose, sneezing, itching, and watery eyes caused by allergies, the common cold, or the flu.
Dexbrompheniramine may also be used for purposes not listed in this medication guide.
Each 5 mL (1 teaspoonful) contains Salbutamol (Expectum) (as sulfate) 1 mg, Guaifenesin (Expectum) 50 mg.
Salbutamol (Expectum)-Guaifenesin (Expectum) (Expectum) delivers the combined benefits of a bronchodilator, Salbutamol (Expectum) and a mucolytic, Guaifenesin (Expectum) in the effective treatment of respiratory tract disorders associated with bronchospasm and excessive or thick, tenacious mucus secretions. Salbutamol (Expectum) and Guaifenesin (Expectum) work in tandem to clear the airway. The two active ingredients relieve pulmonary obstruction caused by bronchospasm and abnormal or excessive bronchial secretions, thereby improving pulmonary ventilation.
Salbutamol (Expectum) has a duration of action of 4-6 hrs in most patients.
Increasing use of β2-agonists may be a sign of worsening asthma. Under these conditions, a reassessment of the patient's therapy plan may be required and concomitant glucocorticosteroid therapy should be considered.
As there may be adverse effects associated with excessive dosing, the dosage or frequency of administration should only be increased on medical advice.
Capsule: Adults and Children >12 years: 1-2 capsule 2 or 3 times daily.
Children 6-12 years: 1 capsule 2 or 3 times daily, <6 years: Not recommended.
Syrup: Adults and Children >12 years: 10-20 mL (Salbutamol (Expectum) 2-4 mg); 6-12 years: 10 mL (Salbutamol (Expectum) 2 mg); 2-6 years: 5-10 mL (Salbutamol (Expectum) 1-2 mg).
All doses to be taken 2 or 3 times daily.
The volumes of syrup quoted are based on a formulation strength of Salbutamol (Expectum) 2 mg/10 mL of syrup.
Elderly or those Known to be Unusually Sensitive to β-adrenergic Stimulant Drugs: Initially, 10 mL (Salbutamol (Expectum) 2 mg) 3 or 4 times a day.
Administration: The capsule may be swallowed whole or the contents may be dispersed in a little water to produce a pleasantly flavored suspension, if preferred.
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What other drugs will affect Expectum?
Salbutamol (Expectum) and nonselective β-blocking drugs eg, propranolol, should not usually be prescribed together.
Salbutamol (Expectum) is not contraindicated in patients under treatment with monoamine oxidase inhibitors (MAOIs).
Incompatibilities: Syrup: Dilution with syrup or sorbitol solution is not recommended as this may result in precipitation of the cellulose-thickening agent. Admixture of Expectum with other liquid preparations is not recommended.
