Acute overdose due to local application of cholisole is unlikely and does not lead to life-threatening situations。
Hypersensitivity to drug ingredients。
Hypersensitivity, pregnancy (I was early in pregnancy).
When used at the same time as amphotericin B and nistatin, the resistance of the clotrimahole may be reduced。
Reduces the effectiveness of nistatin。
This drug is usually well tolerated。 Rarely, hypersensitivity to the ingredients of a drug focuses on allergic reactions such as redness of the oral mucosa, burning and tingling at the site of application of the drug, and urticaria。
If irritation occurs, the drug should be discontinued。
Allergic reaction: bloodshed, itching, rash.
Cholissolous stomatitis。
Dermatophytes, mold and yeast-like fungi, polychromosomiasis, erythrazuma, candidiasis vulvovaginitis, trichomoniasis, fungal diseases complicated by secondary pyoderma, skin and mucous membranes caused by prenatal obstetric hygiene. Fungal lesions.。
Clotrimahole is a microbial of imidahole, the antifungal theory of spectrum。
The antifungal effect violates the synthesis of ergosterol, which is part of the cell membrane of a fungus, causes changes in its structure and properties, and results in cytolysis。
Yeast-like fungi (genus Candida, Torulopsis glabrata, Rhodotorula), mold fungi, and multicolored lichen causative substances Pitilia Sith-Versicolor The original substance of Eritrasma。
It has antibacterial effects against Gram-positive (Staphylococcus and Streptococcus) and Gram-negative bacteria (Bacteroides, Gardnerera-Vaginaris) In relation to, as well Trichomonas-Vaginaris
It has a wide range of effects。 It is active against pathogens, Candida fungi, corynebacterium Minutissimum, staphylococcus spp。, Streptococcus spp., Trichomonas
When applied locally, clotrimazole adsorption from the mucous membrane is negligible。
It is characterized by high penetration。 The concentration in the epidermis is higher than that of the dermis and subcutaneous tissue。 It has virtually no systemic effect。
Corisol
Clotrimazole
From the outside, The cream is applied to the affected area of the skin 2-3 times in a thin layer and gently rubbed。 In the case of a change, it is a split with a row of creams of palm size, 0.5 cm long。
The duration of treatment is individual and depends on the severity and location of the disease。 To achieve full recovery, do not discontinue treatment with cream immediately after the acute symptoms of inflammation or subjective complaints have disappeared。 The treatment period should average about 4 weeks。
Dermatomycosis-3-4 weeks, erythrasma-2-4 weeks, multicolored lichen-1-3 weeks, Candida vulvitis and glansitis-1-2 weeks。
For fungal diseases of the skin of the legs, it is recommended that treatment be continued for about 2 weeks after the symptoms of the disease are relieved。
Externally, in the vagina, the ointment is applied to a thin layer on the affected area of the skin three times until the autism disappears and for another two weeks。 A single dose is a column of 5 mm with a surface area dispersed at the scale of a bar。 For vaginal infections-applicator goes deep into the vagina time per day. Candida vulvovaginitis and Candida glansitis-2-3 times 1-2 weeks。 The total duration of treatment for skin fungal diseases is 3-4 weeks, erythrasma-2-4 weeks, multicolored lichen-1-3 weeks。
