Cloben

Cloben Medicine

Overdose

Symptoms: with prolonged use of beclomethasone on large skin surfaces with impaired integrity or with the use of an occlusive dressing, as well as with prolonged use in children, side effects associated with suppression and insufficiency of the function of the adrenal cortex may develop.

Treatment: discontinuation of the drug and, if necessary, symptomatic therapy.

Contraindications

hypersensitivity,

chickenpox, measles,

tuberculosis of the skin,

post-vaccination skin reactions,

herpes simplex,

cutaneous manifestations of syphilis,

actinomycosis, blastomycosis, sporotrichosis,

trophic ulcers on the background of chronic venous insufficiency,

skin tumors,

lactation period.

Incompatibilities

Is unknown.

Undesirable effects

Side effects are usually mild in nature. Local allergic reactions are possible — redness of the skin, burning sensation and tingling at the site of application of the drug.

Rarely, as with other corticosteroids, acne-like changes, hypopigmentation, striae, skin atrophy, hypertrichosis, telangiectasia, and secondary skin infections may develop.

Therapeutic indications

Fungal infections of the skin, especially accompanied by acute eczematous manifestations:

inguinal athlete's foot, athlete's foot,

microsporia of smooth skin,

candidiasis caused by Candida albicans.

Pharmacotherapeutic group

  • Glucocorticosteroid antifungal agent [Glucocorticosteroids in combinations]

Pharmacodynamic properties

A combined preparation for external use, the effect of which is due to the components included in its composition.

Clotrimazole is an imidazole derivative, a broad-spectrum antifungal agent. The antimycotic effect is associated with a violation of the synthesis of ergosterol, which is part of the cell membrane of fungi, which causes a change in its structure and properties and leads to cell lysis.

To clotrimazole sensitive dermatophytes, yeast-like fungi (genus Candida, Torulopsis glabrata, Rhodotorula), mold fungi, as well as the causative agent of multi-colored lichen Pityriasis versicolor and the causative agent of erythrasma.

It has an antimicrobial effect against gram-positive (staphylococci and streptococci) and gram-negative bacteria (Bacteroides, Gardnerella vaginalis), as well as in relation to Trichomonas vaginalis.

Beclomethasone has anti-inflammatory, anti-allergic, anti-exudative and antipruritic effects. When used externally, beclomethasone suppresses inflammatory and allergic skin reactions as well as reactions associated with increased proliferation, which leads to a reduction in objective symptoms (erythema, edema, lichenification) and subjective sensations (itching, irritation, pain).

Name of the medicinal product

Cloben

Qualitative and quantitative composition

Clotrimazol, Beclometasone

Dosage (Posology) and method of administration

Externally, on pre-washed and dried affected areas of the skin, lightly rubbing, apply a thin layer 2-3 times a day.

With inguinal epidermophytia, smooth skin microsporia and candidiasis, the course of treatment is 2 weeks, with foot epidermophytia-4 weeks. If necessary, long-term use should be used less often-every other day. In the treatment of chronic diseases, treatment should be continued for some time after the disappearance of all symptoms in order to avoid a relapse of the disease.