Hypersensitivity, renal failure, pregnancy (I trimester).
hypersensitivity to the components of the drug,
violation of the integrity of the skin (wounds, deep cuts, trophic ulcers),
children under 18 years of age (no experience of use).
Beta-Escin amorphous (Aescin) enhances the nephrotoxic effect of aminoglycoside antibiotics. Potentiates the action of anticoagulants. Cephalosporins weaken the binding of Beta-Escin amorphous (Aescin)a to plasma proteins, which increases the likelihood of toxic effects.
The drug is well tolerated. In rare cases, nausea, a feeling of heat, palpitations, skin rashes are possible.
Rarely-allergic skin reactions.
The product contains ethanol and frequent application of it to the skin can cause dryness and irritation of the skin.
Chronic venous insufficiency.
Hemorrhoids in the acute stage.
Traumatic soft tissue injuries: edema, inflammation, hematomas.
Prevention and treatment of postoperative edema and hematomas.
Acute nerve root radiculopathy.
pain and swelling of the extremities,
feeling of heaviness in the legs,
nocturnal cramps of the calf muscles,
skin itching caused by venous insufficiency of various degrees,
pain and swelling of a traumatic nature (dislocations, sprains, bruises).
Reduces the permeability of capillaries, has a venotonizing, anti-edematous and anti-inflammatory effect, reduces the fragility of capillaries.
It is absorbed from the gastrointestinal tract by approximately 11%. Cmax it is achieved very quickly, then the escin is redistributed into the tissues. Binding to plasma proteins is significant. It is excreted in bile and urine.
Beta-Escin amorphous (Aescin)
Aescin
Inside, after meals, with plenty of water, 40 mg (2 tablets) 3 times a day. As the clinical effect is achieved, the dose is reduced to 40 mg (2 tables) 2 times a day.
The course of treatment of chronic venous insufficiency — 2 months or more. In the case of acute pathology, the drug is used for 5-14 days at the discretion of the doctor.
In order to prevent postoperative edema and hematomas, the drug is prescribed at least 16 hours before the operation.
Children are prescribed 1/2 dose of adults.
Externally, the gel is applied 2 times a day (usually in the morning and evening) with a thin layer on the corresponding area of the skin, lightly massaging.
