See also:
What is the most important information I should know about Ascorbic acid (Zincovit Cap)?
There are no contraindications to the administration of Ascorbic acid (Zincovit Cap).
See also:
What is the most important information I should know about Biotin (Zincovit Cap)?
SINEQUAN is contraindicated in individuals who have shown hypersensitivity to the drug. Possibility of cross sensitivity with other dibenzoxepines should be kept in mind.
SINEQUAN is contraindicated in patients with glaucoma or a tendency to urinary retention. These disorders should be ruled out, particularly in older patients.
Haemophiliacs, patients with ileus (due to mechanical obstruction).
See also:
What is the most important information I should know about Cyanocobalamin (Zincovit Cap)?
You should not use this medication if you are allergic to cobalt, or if you have Leber's disease. Cyanocobalamin (Zincovit Cap) can lead to optic nerve damage (and possibly blindness) in people with Leber's disease.
To treat pernicious anemia, you will have to use this medication on a regular basis for the rest of your life. Not using the medication can lead to irreversible nerve damage in your spinal cord.
Pernicious anemia is also treated with folic acid to help maintain red blood cells. However, folic acid will not treat Vitamin B12 deficiency and will not prevent possible damage to the spinal cord. Use all of your medications as directed.
Avoid eating or drinking hot foods or liquids within 1 hour before or after using the nasal form of this medication.
Tell your doctor if you develop nasal congestion, a cold, or allergies. The nasal spray may not work as well if you are congested.
Your dose needs may change if you become pregnant, if you breast-feed, or if you eat a vegetarian diet. Tell your doctor about any changes in your diet or medical condition.
See also:
What is the most important information I should know about Folic acid (Zincovit Cap)?
Because it may mask the hematologic abnormalities while neurological damage progresses, Folic acid (Zincovit Cap) should not be used in the therapy of patients with vitamin B12 deficiency of any cause, unless there is associated folate deficiency. The Folic acid (Zincovit Cap) content of one tablet a day however, is unlikely to mask pernicious anemia should this condition be present. Also, pregnancy during pernicious anemia is very rare.
See also:
What is the most important information I should know about Pyridoxine hydrochloride (Zincovit Cap)?
Contraindications for Vitamin B6 (Pyridoxine hydrochloride (Zincovit Cap)-HCl Microencapsulated)
Vitamin B6 is contraindicated in those hypersensitive to any component of a vitamin B6-containing product.
See also:
What is the most important information I should know about Riboflavin (Zincovit Cap)?
None well documented.
do not use in the treatment of leber disease or tobaco intoxication.
See also:
What is the most important information I should know about Vitamin A acetate (Zincovit Cap)?
The intravenous administration. Hypervitaminosis A. Sensitivity to any of the ingredients in this preparation. Use in Pregnancy: Safety of amounts exceeding 6,000 Units of Vitamin A acetate (Zincovit Cap) daily during pregnancy has not been established at this time. The use of Vitamin A acetate (Zincovit Cap) in excess of the recommended dietary allowance may cause fetal harm when administered to a pregnant woman. Animal reproduction studies have shown fetal abnormalities associated with overdosage in several species. Malformations of the central nervous system, the eye, the palate, and the urogenital tract are recorded. Vitamin A acetate (Zincovit Cap) in excess of the recommended dietary allowance is contraindicated in women who are or may become pregnant. If Vitamin A acetate (Zincovit Cap) is used during pregnancy, or if the patient becomes pregnant while taking Vitamin A acetate (Zincovit Cap), the patient should be apprised of the potential hazard to the fetus.
See also:
What is the most important information I should know about Vitamin D (Zincovit Cap)?
OTC labeling: Replesta products only: When used for self-medication, do not use if you have hypercalcemia, primary hyperparathyroidism, sarcoidosis, hypervitaminosis D, Williams syndrome, or are pregnant.
Documentation of allergenic cross-reactivity for Vitamin D (Zincovit Cap) is limited. However, because of similarities in chemical structure and/or pharmacologic actions, the possibility of cross-sensitivity cannot be ruled out with certainty.
See also:
What are the possible side effects of Ascorbic acid (Zincovit Cap)?
Applies to Ascorbic acid (Zincovit Cap): oral capsule, oral capsule extended release, oral capsule liquid filled, oral granule, oral liquid, oral lozenge/troche, oral powder, oral powder for solution, oral powder for suspension, oral solution, oral syrup, oral tablet, oral tablet chewable, oral tablet extended release, oral wafer
In addition to its needed effects, some unwanted effects may be caused by Ascorbic acid (Zincovit Cap) (the active ingredient contained in Ascorbic acid (Zincovit Cap)). In the event that any of these side effects do occur, they may require medical attention.
Severity: ModerateIf any of the following side effects occur while taking Ascorbic acid (Zincovit Cap), check with your doctor or nurse as soon as possible:
Less common or rare: - with high doses
Some of the side effects that can occur with Ascorbic acid (Zincovit Cap) may not need medical attention. As your body adjusts to the medicine during treatment these side effects may go away. Your health care professional may also be able to tell you about ways to reduce or prevent some of these side effects. If any of the following side effects continue, are bothersome or if you have any questions about them, check with your health care professional:
Less common or rare: - with high doses
See also:
What are the possible side effects of Biotin (Zincovit Cap)?
Adverse reactions associated with Biotin (Zincovit Cap) supplementation are rare in the medical literature; however, urticaria and gastrointestinal upset have been reported. As with any oral treatment, if patients experience any adverse reactions or side effects, they should inform their physicians immediately and discontinue use.
See also:
What are the possible side effects of Calcium pantothenate (Zincovit Cap)?
Cardiovascular
Nasal spray
Angina pectoris, hypertension (1% to 3%).
CNS
Nasal spray: Fatigue, depression, dizziness, paresthesia (1% to 3%). Injectable: Poor appetite; abdominal pain.
Dermatologic
Nasal spray
Erythematous rash (1% to 3%).
Injectable
Pruritus of ear lobes; skin rash.
EENT
Nasal spray
Rhinitis (12%); abnormal lacrimation, conjunctivitis (1% to 3%).
Injectable
Eye pain.
GI
Nasal spray
Abdominal pain, constipation, diarrhea, dyspepsia, nausea (1% to 3%).
Injectable
Nausea with or without vomiting (10%); salty taste.
Genitourinary
Nasal spray
Cystitis (1% to 3%).
Injectable
Nocturia.
Hematologic-Lymphatic
Nasal spray
Infection, lymphadenopathy (1% to 3%).
Local
Injectable
Inflammation at subcutaneous or IM site (10%).
Musculoskeletal
Nasal spray
Back pain (5%); arthralgia (4%); arthrosis, myalgia (1% to 3%).
Respiratory
Nasal spray
Epistaxis (4%); bronchospasm, sinusitis, upper respiratory tract infection (1% to 3%).
Miscellaneous
Nasal spray
Influenza-like symptoms (1% to 3%).
Injectable
Death caused by anaphylaxis (1 case), feet edema, feverish sensation.
See also:
What are the possible side effects of Cyanocobalamin (Zincovit Cap)?
The incidence of adverse experiences described in the Table below are based on data from a short-term clinical trial in vitamin B12 deficient patients in hematologic remission receiving Cyanocobalamin (Zincovit Cap) (Cyanocobalamin (Zincovit Cap), USP) Gel for Intranasal Administration (N=24) and intramuscular vitamin B12 (N=25). In the pharmacokinetic study comparing Cyanocobalamin (Zincovit Cap) Nasal Spray and Cyanocobalamin (Zincovit Cap) Nasal Gel, the incidence of adverse events was similar.
The intensity of the reported adverse experiences following the administration of Cyanocobalamin (Zincovit Cap) (Cyanocobalamin (Zincovit Cap), USP) Gel for Intranasal Administration and intramuscular vitamin B12 were generally mild. One patient reported severe headache following intramuscular dosing. Similarly, a few adverse experiences of moderate intensity were reported following intramuscular dosing (two headaches and rhinitis; one dyspepsia, arthritis, and dizziness), and dosing with Cyanocobalamin (Zincovit Cap) (Cyanocobalamin (Zincovit Cap), USP) Gel for Intranasal Administration (one headache, infection, and paresthesia).
The majority of the reported adverse experiences following dosing with Cyanocobalamin (Zincovit Cap) (Cyanocobalamin (Zincovit Cap), USP) Gel for Intranasal Administration and intramuscular vitamin B12 were judged to be intercurrent events. For the other reported adverse experiences, the relationship to study drug was judged as "possible" or "remote". Of the adverse experiences judged to be of "possible" relationship to the study drug, anxiety, incoordination, and nervousness were reported following intramuscular vitamin B12 and headache, nausea, and rhinitis were reported following dosing with Cyanocobalamin (Zincovit Cap) (Cyanocobalamin (Zincovit Cap), USP) Gel for Intranasal Administration.
The following adverse reactions have been reported with parenteral vitamin B12:
Generalized: Anaphylactic shock and death.
Cardiovascular: Pulmonary edema and congestive heart failure early in treatment; peripheral vascular thrombosis.
Hematological: Polycythemia vera.
Gastrointestinal: Mild transient diarrhea.
Dermatological: Itching; transitory exanthema.
Miscellaneous: Feeling of swelling of the entire body.
See also:
What are the possible side effects of Folic acid (Zincovit Cap)?
Allergic sensitization has been reported following both oral and parenteral administration of Folic acid (Zincovit Cap).
Folic acid (Zincovit Cap) is relatively nontoxic in man. Rare instances of allergic responses to Folic acid (Zincovit Cap) preparations have been reported and have included erythema, skin rash, itching, general malaise, and respiratory difficulty due to bronchospasm. One patient experienced symptoms suggesting anaphylaxis following injection of the drug. Gastrointestinal side effects, including anorexia, nausea, abdominal distention, flatulence, and a bitter or bad taste, have been reported in patients receiving 15 mg Folic acid (Zincovit Cap) daily for 1 month. Other side effects reported in patients receiving 15 mg daily include altered sleep patterns, difficulty in concentrating, irritability, overactivity, excitement, mental depression, confusion, and impaired judgment. Decreased vitamin B12 serum levels may occur in patients receiving prolonged Folic acid (Zincovit Cap) therapy.
In an uncontrolled study, orally administered Folic acid (Zincovit Cap) was reported to increase the incidence of seizures in some epileptic patients receiving phenobarbital, primidone, or diphenylhydantoin. Another investigator reported decreased diphenylhydantoin serum levels in folate-deficient patients receiving diphenylhydantoin who were treated with 5 mg or 15 mg of Folic acid (Zincovit Cap) daily.
CALL YOUR DOCTOR FOR MEDICAL ADVICE ABOUT SIDE EFFECTS. YOU MAY REPORT SIDE EFFECTS TO THE FDA AT 1-800-FDA-1088 OR LEADING PHARMA, LLC AT 844-740-7500.
See also:
What are the possible side effects of Niacinamide (Zincovit Cap)?
Applies to Niacinamide (Zincovit Cap): tablets
Check with your doctor if any of these most COMMON side effects persist or become bothersome:
Diarrhea; dizziness; headache; itching; nausea; stomach upset; temporary feeling of warmth or flushing of the skin.
Seek medical attention right away if any of these SEVERE side effects occur while taking Niacinamide (Zincovit Cap):
Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); black, tarry, or bloody stools; changes in vision; dark urine; decreased urination; fast or irregular heartbeat; loss of appetite; muscle pain or weakness; numbness or persistent tingling of the skin; persistent nausea, vomiting, or general "unwell" feeling; severe or prolonged flushing of the skin; stomach pain; swelling of the hands, legs, or feet; vomit that looks like coffee grounds; yellowing of the skin or eyes.
See also:
What are the possible side effects of Pyridoxine hydrochloride (Zincovit Cap)?
CNS
Neuropathy; unstable gait; drowsiness; somnolence.
EENT
Perioral numbness.
Miscellaneous
Numbness of feet; decreased sensation to touch, temperature or vibration; paresthesia; low serum Pyridoxine hydrochloride (Zincovit Cap) levels; burning/stinging at IM injection site; photoallergic reaction; ataxia.
See also:
What are the possible side effects of Riboflavin (Zincovit Cap)?
Frequency not defined: Genitourinary: Urine discoloration (yellow-orange)
anaphylactic reactions rarely, severe cases can cause death, urine yellow colouration,peripheral neuropathy in case of prolonged useage, arrythmias,
See also:
What are the possible side effects of Vitamin A acetate (Zincovit Cap)?
This vitamin usually has no side effects when used in recommended doses. If you have any unusual effects, contact your doctor or pharmacist promptly.
A very serious allergic reaction to this vitamin is rare. However, seek immediate medical attention if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.
This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.
In the US -
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch.
In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.
See also:
What are the possible side effects of Vitamin D (Zincovit Cap)?
Vitamin D (Zincovit Cap) at normal doses usually has no side effects. If you have any unusual effects, contact your doctor or pharmacist promptly.
If your doctor has directed you to take this medication, remember that he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.
Too much Vitamin D (Zincovit Cap) can cause harmful high Vitamin D (Zincovit Cap) levels. Tell your doctor right away if any of these signs of high Vitamin D (Zincovit Cap)/Vitamin D (Zincovit Cap) levels occur: nausea/vomiting, constipation, loss of appetite, increased thirst, increased urination, mental/mood changes, unusual tiredness.
A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.
This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.
In the US -
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch.
In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.
For systemic use of Ascorbic acid (Zincovit Cap) Atlantic Laboratories: prevention and treatment of hypo- and avitaminosis of Ascorbic acid (Zincovit Cap); providing increased need for Ascorbic acid (Zincovit Cap) during growth, pregnancy, lactation, with heavy loads, fatigue and during recovery after prolonged severe illness; in winter with an increased risk of infectious diseases.
For intravaginal use: chronic or recurrent vaginitis (bacterial vaginosis, nonspecific vaginitis) caused by the anaerobic flora (due to changes in pH of the vagina) in order to normalize disturbed vaginal microflora.
An indication is a term used for the list of condition or symptom or illness for which the medicine is prescribed or used by the patient. For example, acetaminophen or paracetamol is used for fever by the patient, or the doctor prescribes it for a headache or body pains. Now fever, headache and body pains are the indications of paracetamol. A patient should be aware of the indications of medications used for common conditions because they can be taken over the counter in the pharmacy meaning without prescription by the Physician.skin disorders, Biotin (Zincovit Cap) deficiency, digestive disorders
An indication is a term used for the list of condition or symptom or illness for which the medicine is prescribed or used by the patient. For example, acetaminophen or paracetamol is used for fever by the patient, or the doctor prescribes it for a headache or body pains. Now fever, headache and body pains are the indications of paracetamol. A patient should be aware of the indications of medications used for common conditions because they can be taken over the counter in the pharmacy meaning without prescription by the Physician.Coenzyme A (metabolite of dexpanthenol) is important for deep penetrating moisturizer; stimulates epithelization; has wound healing effect; has an anti-inflammatory effect.
Only the D-Calcium pantothenate (Zincovit Cap) is the provitamin of D-Pantothenic acid (vitamin B5), not the L-Calcium pantothenate (Zincovit Cap).
A cream with dexpanthenol regularly applied to the skin improves the moisture content of dry skin significantly.
A cream with 5% dexpanthenol accelerates the healing of superficial wounds by approximately 30%.
An ointment with dexpanthenol prevents erythema due to UV light.
Dexpanthenol ointment also protects the lips against solar herpes, Sun burns, mild burns, skin irritations, dry or cracked skin, cosmetic or shaving rashes, post chemical peeling treatment, post laser resurfacing treatment ( 11th -15th day).
Dexpanthenol is effective for preventing / treating nappy dermatitis in infants.
An indication is a term used for the list of condition or symptom or illness for which the medicine is prescribed or used by the patient. For example, acetaminophen or paracetamol is used for fever by the patient, or the doctor prescribes it for a headache or body pains. Now fever, headache and body pains are the indications of paracetamol. A patient should be aware of the indications of medications used for common conditions because they can be taken over the counter in the pharmacy meaning without prescription by the Physician.Cyanocobalamin (Zincovit Cap) Nasal Spray is indicated for the maintenance of normal hematologic status in pernicious anemia patients who are in remission following intramuscular vitamin B12 therapy and who have no nervous system involvement.
Cyanocobalamin (Zincovit Cap) Nasal Spray is also indicated as a supplement for other vitamin B12 deficiencies, including:
I. Dietary deficiency of vitamin B12 occurring in strict vegetarians (Isolated vitamin B12 deficiency is very rare).
II. Malabsorption of vitamin B12 resulting from structural or functional damage to the stomach, where intrinsic factor is secreted, or to the ileum, where intrinsic factor facilitates vitamin B12 absorption. These conditions include HIV infection, AIDS, Crohn's disease, tropical sprue, and nontropical sprue (idiopathic steatorrhea, gluten-induced enteropathy). Folate deficiency in these patients is usually more severe than vitamin B12 deficiency.
III. Inadequate secretion of intrinsic factor, resulting from lesions that destroy the gastric mucosa (ingestion of corrosives, extensive neoplasia), and a number of conditions associated with a variable degree of gastric atrophy (such as multiple sclerosis, HIV infection, AIDS, certain endocrine disorders, iron deficiency, and subtotal gastrectomy). Total gastrectomy always produces vitamin B12 deficiency. Structural lesions leading to vitamin B12 deficiency include regional ileitis, ileal resections, malignancies, etc.
IV. Competition for vitamin B12 by intestinal parasites or bacteria. The fish tapeworm (Diphyllobothrium latum) absorbs huge quantities of vitamin B12 and infested patients often have associated gastric atrophy. The blind loop syndrome may produce deficiency of vitamin B12 or folate.
V. Inadequate utilization of vitamin B12. This may occur if antimetabolites for the vitamin are employed in the treatment of neoplasia.
It may be possible to treat the underlying disease by surgical correction of anatomic lesions leading to small bowel bacterial overgrowth, expulsion of fish tapeworm, discontinuation of drugs leading to vitamin malabsorption, use of a gluten-free diet in non-tropical sprue, or administration of antibiotics in tropical sprue. Such measures remove the need for long-term administration of vitamin B12.
Requirements of vitamin B12 in excess of normal (due to pregnancy, thyrotoxicosis, hemolytic anemia, hemorrhage, malignancy, hepatic and renal disease) can usually be met with intranasal or oral supplementation.
Cyanocobalamin (Zincovit Cap) Nasal Spray is not suitable for vitamin B12 absorption test (Schilling Test).
An indication is a term used for the list of condition or symptom or illness for which the medicine is prescribed or used by the patient. For example, acetaminophen or paracetamol is used for fever by the patient, or the doctor prescribes it for a headache or body pains. Now fever, headache and body pains are the indications of paracetamol. A patient should be aware of the indications of medications used for common conditions because they can be taken over the counter in the pharmacy meaning without prescription by the Physician.Folic acid (Zincovit Cap) is used in the treatment and prevention of the folate deficiency state. It does not correct folate deficiency due to dihydrofolate reductase inhibitors. Folic acid (Zincovit Cap) is also used in women of child-bearing potential and pregnant women to protect against neural tube defects in their offspring. It is also used for the treatment of folate-deficient megaloblastic anaemia, chronic haemolytic states such as thalassaemia major or sickle-cell anaemia.
An indication is a term used for the list of condition or symptom or illness for which the medicine is prescribed or used by the patient. For example, acetaminophen or paracetamol is used for fever by the patient, or the doctor prescribes it for a headache or body pains. Now fever, headache and body pains are the indications of paracetamol. A patient should be aware of the indications of medications used for common conditions because they can be taken over the counter in the pharmacy meaning without prescription by the Physician.* Sideroblastic anaemia
* Treatment and prophylaxis of vitamin B6 deficiency states
An indication is a term used for the list of condition or symptom or illness for which the medicine is prescribed or used by the patient. For example, acetaminophen or paracetamol is used for fever by the patient, or the doctor prescribes it for a headache or body pains. Now fever, headache and body pains are the indications of paracetamol. A patient should be aware of the indications of medications used for common conditions because they can be taken over the counter in the pharmacy meaning without prescription by the Physician.Oral
Prophylaxis of Riboflavin (Zincovit Cap) deficiency
Adult: 1-2 mg daily.
Incompatibility: Incompatible with alkaline solutions and with tetracycline, erythromycin and streptomycin.
OralRiboflavin (Zincovit Cap) deficiency
Adult: Up to 30 mg daily in divided doses.
Child: 3-10 mg daily.
Incompatibility: Incompatible with alkaline solutions and with tetracycline, erythromycin and streptomycin.
OralMicrocytic anaemia
Adult: Associated with splenomegaly and glutathione reductase deficiency: 10 mg daily for 10 days.
Incompatibility: Incompatible with alkaline solutions and with tetracycline, erythromycin and streptomycin.
An indication is a term used for the list of condition or symptom or illness for which the medicine is prescribed or used by the patient. For example, acetaminophen or paracetamol is used for fever by the patient, or the doctor prescribes it for a headache or body pains. Now fever, headache and body pains are the indications of paracetamol. A patient should be aware of the indications of medications used for common conditions because they can be taken over the counter in the pharmacy meaning without prescription by the Physician.treatment of vitamin B deficiencies and prevention of it.
An indication is a term used for the list of condition or symptom or illness for which the medicine is prescribed or used by the patient. For example, acetaminophen or paracetamol is used for fever by the patient, or the doctor prescribes it for a headache or body pains. Now fever, headache and body pains are the indications of paracetamol. A patient should be aware of the indications of medications used for common conditions because they can be taken over the counter in the pharmacy meaning without prescription by the Physician.For the treatment of Vitamin A acetate (Zincovit Cap) deficiency. (Retinitis pigmentosa; Vitamin A acetate (Zincovit Cap) deficiency; Xerophthalmia;)
An indication is a term used for the list of condition or symptom or illness for which the medicine is prescribed or used by the patient. For example, acetaminophen or paracetamol is used for fever by the patient, or the doctor prescribes it for a headache or body pains. Now fever, headache and body pains are the indications of paracetamol. A patient should be aware of the indications of medications used for common conditions because they can be taken over the counter in the pharmacy meaning without prescription by the Physician.This medicine is indicated in all conditions where there is a disturbance of Vitamin D (Zincovit Cap) metabolism due to impaired 1-α hydroxylation such as when there is reduced renal function. The main indications are:
a) Renal osteodystrophy
b) Hyperparathyroidism (with bone disease)
c) Hypoparathyroidism
d) Neonatal hypocalcaemia
e) Nutritional and malabsorptive rickets and osteomalacia
f) Pseudo-deficiency (D-dependent) rickets and osteomalacia
g) Hypophosphataemic Vitamin D (Zincovit Cap) resistant rickets and osteomalacia
Ascorbic acid (Zincovit Cap) (Ascorbic acid (Zincovit Cap)) occurs naturally in foods such as citrus fruit, tomatoes, potatoes, and leafy vegetables. Ascorbic acid (Zincovit Cap) is important for bones and connective tissues, muscles, and blood vessels. Ascorbic acid (Zincovit Cap) also helps the body absorb iron, which is needed for red blood cell production.
Ascorbic acid (Zincovit Cap) is used to treat and prevent Ascorbic acid (Zincovit Cap) deficiency.
Ascorbic acid (Zincovit Cap) may also be used for purposes not listed in this medication guide.
Biotin (Zincovit Cap) is a form of vitamin B found in foods. Biotin (Zincovit Cap) helps the body break down fats, carbohydrates, and other substances.
Biotin (Zincovit Cap) has been used in alternative medicine as a likely effective aid in treating or preventing Biotin (Zincovit Cap) deficiency. Biotin (Zincovit Cap) deficiency can be caused by malnutrition, rapid weight loss, long-term tube feeding, and other medical conditions.
Biotin (Zincovit Cap) has also been used to treat seborrhea (skin rash) in babies. However, research has shown that Biotin (Zincovit Cap) may not be effective in treating this condition.
Other uses not proven with research have included treating brittle nails or thinning hair, diabetes, nerve pain, and other conditions.
It is not certain whether Biotin (Zincovit Cap) is effective in treating any medical condition. Medicinal use of this product has not been approved by the FDA. Biotin (Zincovit Cap) should not be used in place of medication prescribed for you by your doctor.
Biotin (Zincovit Cap) is often sold as an herbal supplement. There are no regulated manufacturing standards in place for many herbal compounds and some marketed supplements have been found to be contaminated with toxic metals or other drugs. Herbal/health supplements should be purchased from a reliable source to minimize the risk of contamination.
Biotin (Zincovit Cap) may also be used for purposes not listed in this product guide.
Cyanocobalamin (Zincovit Cap) nasal spray contains cyanocobalamin, a man-made form of vitamin B12. Vitamin B12 is important for growth, cell reproduction, blood formation, and protein and tissue synthesis.
Cyanocobalamin (Zincovit Cap) nasal spray is used to treat vitamin B12 deficiency in people with pernicious anemia and other conditions.
Cyanocobalamin (Zincovit Cap) nasal spray is usually given after treatment with an injection form of this medicine.
Cyanocobalamin (Zincovit Cap) may also be used for purposes not listed in this medication guide.
Vitamins are compounds that you must have for growth and health. They are needed in small amounts only and are usually available in the foods that you eat. Folic acid (Zincovit Cap) (vitamin B 9) is necessary for strong blood.
Lack of Folic acid (Zincovit Cap) may lead to anemia (weak blood). Your health care professional may treat this by prescribing Folic acid (Zincovit Cap) for you.
Some conditions may increase your need for Folic acid (Zincovit Cap). These include:
In addition, infants smaller than normal, breast-fed infants, or those receiving unfortified formulas (such as evaporated milk or goat's milk) may need additional Folic acid (Zincovit Cap).
Increased need for Folic acid (Zincovit Cap) should be determined by your health care professional.
Some studies have found that Folic acid (Zincovit Cap) taken by women before they become pregnant and during early pregnancy may reduce the chances of certain birth defects (neural tube defects).
Claims that Folic acid (Zincovit Cap) and other B vitamins are effective for preventing mental problems have not been proven. Many of these treatments involve large and expensive amounts of vitamins.
Injectable Folic acid (Zincovit Cap) is given by or under the direction of your health care professional. Another form of Folic acid (Zincovit Cap) is available without a prescription.
An indication is a term used for the list of condition or symptom or illness for which the medicine is prescribed or used by the patient. For example, acetaminophen or paracetamol is used for fever by the patient, or the doctor prescribes it for a headache or body pains. Now fever, headache and body pains are the indications of paracetamol. A patient should be aware of the indications of medications used for common conditions because they can be taken over the counter in the pharmacy meaning without prescription by the Physician.Treating acne.
Niacinamide (Zincovit Cap) gel is a vitamin B supplement. Exactly how Niacinamide (Zincovit Cap) gel works is unknown.
Pyridoxine hydrochloride (Zincovit Cap) is vitamin B6. Vitamins occur naturally in foods such as meat, poultry, nuts, whole grains, bananas, and avocados. Vitamin B6 is important for many processes in the body.
Pyridoxine hydrochloride (Zincovit Cap) is used to treat or prevent vitamin B6 deficiency. It is also used to treat a certain type of anemia (lack of red blood cells). Pyridoxine hydrochloride (Zincovit Cap) injection is also used to treat some types of seizure in babies.
Pyridoxine hydrochloride (Zincovit Cap) taken by mouth (oral) is available without a prescription. Injectable Pyridoxine hydrochloride (Zincovit Cap) must be given by a healthcare professional.
Pyridoxine hydrochloride (Zincovit Cap) may also be used for purposes not listed in this medication guide.
Vitamins are compounds that you must have for growth and health. They are needed in small amounts only and are usually available in the foods that you eat. Riboflavin (Zincovit Cap) (vitamin B 2) is needed to help break down carbohydrates, proteins, and fats. It also makes it possible for oxygen to be used by your body.
Lack of Riboflavin (Zincovit Cap) may lead to itching and burning eyes, sensitivity of eyes to light, sore tongue, itching and peeling skin on the nose and scrotum, and sores in the mouth. Your doctor may treat this condition by prescribing Riboflavin (Zincovit Cap) for you.
Some conditions may increase your need for Riboflavin (Zincovit Cap). These include:
In addition, Riboflavin (Zincovit Cap) may be given to infants with high blood levels of bilirubin (hyperbilirubinemia).
Increased need for Riboflavin (Zincovit Cap) should be determined by your health care professional.
Claims that Riboflavin (Zincovit Cap) is effective for treatment of acne, some kinds of anemia (weak blood), migraine headaches, and muscle cramps have not been proven.
Oral forms of Riboflavin (Zincovit Cap) are available without a prescription.Vitamins are compounds that you must have for growth and health. They are needed in small amounts only and are usually available in the foods that you eat. Vitamin A acetate (Zincovit Cap) is needed for night vision and for growth of skin, bones, and male and female reproductive organs. In pregnant women Vitamin A acetate (Zincovit Cap) is necessary for the growth of a healthy fetus.
Lack of Vitamin A acetate (Zincovit Cap) may lead to a rare condition called night blindness (problems seeing in the dark), as well as dry eyes, eye infections, skin problems, and slowed growth. Your health care professional may treat these problems by prescribing Vitamin A acetate (Zincovit Cap) for you.
Some conditions may increase your need for Vitamin A acetate (Zincovit Cap). These include:
In addition, infants receiving unfortified formula may need Vitamin A acetate (Zincovit Cap) supplements.
Vitamin A acetate (Zincovit Cap) absorption will be decreased in any condition in which fat is poorly absorbed.
Increased need for Vitamin A acetate (Zincovit Cap) should be determined by your health care professional.
Claims that Vitamin A acetate (Zincovit Cap) is effective for treatment of conditions such as acne or lung diseases, or for treatment of eye problems, wounds, or dry or wrinkled skin not caused by lack of Vitamin A acetate (Zincovit Cap) have not been proven. Although Vitamin A acetate (Zincovit Cap) is being used to prevent certain types of cancer, some experts feel there is not enough information to show that this is effective, particularly in well-nourished individuals.
Injectable Vitamin A acetate (Zincovit Cap) is given by or under the supervision of a health care professional. Other forms of Vitamin A acetate (Zincovit Cap) are available without a prescription.
Vitamins are compounds that you must have for growth and health. They are needed in small amounts only and are available in the foods that you eat. Vitamin D (Zincovit Cap) is necessary for strong bones and teeth.
Lack of Vitamin D (Zincovit Cap) may lead to a condition called rickets, especially in children, in which bones and teeth are weak. In adults it may cause a condition called osteomalacia, in which Vitamin D (Zincovit Cap) is lost from bones so that they become weak. Your doctor may treat these problems by prescribing Vitamin D (Zincovit Cap) for you. Vitamin D (Zincovit Cap) is also sometimes used to treat other diseases in which Vitamin D (Zincovit Cap) is not used properly by the body.
Ergocalciferol is the form of Vitamin D (Zincovit Cap) used in vitamin supplements.
Some conditions may increase your need for Vitamin D (Zincovit Cap). These include:
In addition, individuals and breast-fed infants who lack exposure to sunlight, as well as dark-skinned individuals, may be more likely to have a Vitamin D (Zincovit Cap) deficiency. Increased need for Vitamin D (Zincovit Cap) should be determined by your health care professional.
Alfacalcidol, calcifediol, calcitriol, and dihydrotachysterol are forms of Vitamin D (Zincovit Cap) used to treat hypocalcemia (not enough Vitamin D (Zincovit Cap) in the blood). Alfacalcidol, calcifediol, and calcitriol are also used to treat certain types of bone disease that may occur with kidney disease in patients who are undergoing kidney dialysis.
Claims that Vitamin D (Zincovit Cap) is effective for treatment of arthritis and prevention of nearsightedness or nerve problems have not been proven. Some psoriasis patients may benefit from Vitamin D (Zincovit Cap) supplements; however, controlled studies have not been performed.
Injectable Vitamin D (Zincovit Cap) is given by or under the supervision of a health care professional. Some strengths of ergocalciferol and all strengths of alfacalcidol, calcifediol, calcitriol, and dihydrotachysterol are available only with your doctor's prescription. Other strengths of ergocalciferol are available without a prescription. However, it may be a good idea to check with your health care professional before taking Vitamin D (Zincovit Cap) on your own. Taking large amounts over long periods may cause serious unwanted effects.
Each tablet contains Ascorbic acid (Zincovit Cap) 500 mg.
Ascorbic acid (Zincovit Cap) (Ascorbic acid (Zincovit Cap)) is a vitamin that is freely soluble in water. The superior formulation of Ascorbic acid (Zincovit Cap) (Ascorbic acid (Zincovit Cap)) assures substantial amounts per dose for prophylaxis and treatment of Ascorbic acid (Zincovit Cap) deficiencies. This preparation has a very delectable grape (Ascorbic acid (Zincovit Cap) Tablet) flavors.
A dibenzoxepin tricyclic compound. It displays a range of pharmacological actions including maintaining adrenergic innervation. Its mechanism of action is not fully understood, but it appears to block reuptake of monoaminergic neurotransmitters into presynaptic terminals. It also possesses anticholinergic activity and modulates antagonism of histamine H(1)- and H(2)-receptors.
Calcium pantothenate (Zincovit Cap) chloride is an ionic compound of Calcium pantothenate (Zincovit Cap) and chlorine. It is highly soluble in water and it is deliquescent. It is a salt that is solid at room temperature, and it behaves as a typical ionic halide. It has several common applications such as brine for refrigeration plants, ice and dust control on roads, and in cement. It can be produced directly from limestone, but large amounts are also produced as a by-product of the Solvay process. Because of its hygroscopic nature, it must be kept in tightly-sealed containers.
Cyanocobalamin (Zincovit Cap) (commonly known as Vitamin B12) is the most chemically complex of all the vitamins. Cyanocobalamin (Zincovit Cap)'s structure is based on a corrin ring, which, although similar to the porphyrin ring found in heme, chlorophyll, and cytochrome, has two of the pyrrole rings directly bonded. The central metal ion is Co (cobalt). Cyanocobalamin (Zincovit Cap) cannot be made by plants or by animals, as the only type of organisms that have the enzymes required for the synthesis of Cyanocobalamin (Zincovit Cap) are bacteria and archaea. Higher plants do not concentrate Cyanocobalamin (Zincovit Cap) from the soil and so are a poor source of the substance as compared with animal tissues. Cyanocobalamin (Zincovit Cap) is naturally found in foods including meat (especially liver and shellfish), eggs, and milk products. [HMDB]
A member of the vitamin B family that stimulates the hematopoietic system. It is present in the liver and kidney and is found in mushrooms, spinach, yeast, green leaves, and grasses (poaceae). Folic acid (Zincovit Cap) is used in the treatment and prevention of folate deficiencies and megaloblastic anemia. [PubChem]
Niacinamide (Zincovit Cap), also called as nicotinamide (vitamin B3), is prescribed for the treatment of niacin deficiency disorders including pellagra. Niacinamide (Zincovit Cap) should not be used for treatment of hyperlipidemia.
Pyridoxine hydrochloride (Zincovit Cap) is the 4-methanol form of vitamin B6 and is converted to pyridoxal 5-phosphate in the body. Pyridoxal 5-phosphate is a coenzyme for synthesis of amino acids, neurotransmitters (serotonin, norepinephrine), sphingolipids, aminolevulinic acid. Although Pyridoxine hydrochloride (Zincovit Cap) and vitamin B6 are still frequently used as synonyms, especially by medical researchers, this practice is erroneous and sometimes misleading. [PubChem]
Nutritional factor found in milk, eggs, malted barley, liver, kidney, heart, and leafy vegetables. The richest natural source is yeast. It occurs in the free form only in the retina of the eye, in whey, and in urine; its principal forms in tissues and cells are as flavin mononucleotide and flavin-adenine dinucleotide. [PubChem]
Vitamin A acetate (Zincovit Cap) (Glucoenergan, Reactivan) is a stimulant which was developed in the 1960s as an appetite suppressant, but was later withdrawn for this application due to problems with dependence and abuse. It is around half the potency of dexamphetamine, and is prescribed at a dose of 10-60mg, although abusers of the drug tend to rapidly develop tolerance and escalate their dose. Reactivan is still rarely used for treating depressive day-time fatigue, lack of concentration and lethargy, particularly in individuals who have chronic medical conditions, as its favourable safety profile makes it the most suitable drug in some cases.
Use Ascorbic acid (Zincovit Cap) as directed by your doctor. Check the label on the medicine for exact dosing instructions.
Ask your health care provider any questions you may have about how to use Ascorbic acid (Zincovit Cap).
Use Cyanocobalamin (Zincovit Cap) (b12) spray as directed by your doctor. Check the label on the medicine for exact dosing instructions.
Ask your health care provider any questions you may have about how to use Cyanocobalamin (Zincovit Cap) (b12) spray.
Use Folic acid (Zincovit Cap) as directed by your doctor. Check the label on the medicine for exact dosing instructions.
Ask your health care provider any questions you may have about how to use Folic acid (Zincovit Cap).
Use Niacinamide (Zincovit Cap) gel as directed by your doctor. Check the label on the medicine for exact dosing instructions.
Ask your health care provider any questions you may have about how to use Niacinamide (Zincovit Cap) gel.
Use Pyridoxine hydrochloride (Zincovit Cap) (vitamin b6) as directed by your doctor. Check the label on the medicine for exact dosing instructions.
Ask your health care provider any questions you may have about how to use Pyridoxine hydrochloride (Zincovit Cap) (vitamin b6).
A surgeon or other healthcare provider will give you this medicine as part of your corneal collagen crosslinking procedure.
You will be given numbing eyedrops to prepare you for the procedure. You may also be given a sedative or anesthesia to help you relax. Although you will most likely be awake during the procedure, you should feel little or no discomfort. A special device will be placed around your eyelids to keep them open during the procedure.
Your eye surgeon will place Riboflavin (Zincovit Cap) ophthalmic drops into your eyes about every 2 minutes during the procedure.
After the procedure, the surgeon will place a contact lens on the treated eye to protect it for a short time.
Call your doctor right away if the contact lens falls out or feels like it is out of place inside your eye.
You may also need to use antibiotic or steroid eyedrops to prevent infection and reduce swelling after your procedure. Carefully follow all after-care instructions and do not miss any follow-up appointments.
There are specific as well as general uses of a drug or medicine. A medicine can be used to prevent a disease, treat a disease over a period or cure a disease. It can also be used to treat the particular symptom of the disease. The drug use depends on the form the patient takes it. It may be more useful in injection form or sometimes in tablet form. The drug can be used for a single troubling symptom or a life-threatening condition. While some medications can be stopped after few days, some drugs need to be continued for prolonged period to get the benefit from it.Ascorbic acid (Zincovit Cap) (Ascorbic acid (Zincovit Cap)) is used to prevent or treat low levels of Ascorbic acid (Zincovit Cap) in people who do not get enough of the vitamin from their diets. Most people who eat a normal diet do not need extra Ascorbic acid (Zincovit Cap). Low levels of Ascorbic acid (Zincovit Cap) can result in a condition called scurvy. Scurvy may cause symptoms such as rash, muscle weakness, joint pain, tiredness, or tooth loss.
Ascorbic acid (Zincovit Cap) plays an important role in the body. It is needed to maintain the health of skin, cartilage, teeth, bone, and blood vessels. It is also used to protect your body's cells from damage. It is known as an antioxidant.
OTHER USES: This section contains uses of this drug that are not listed in the approved professional labeling for the drug but that may be prescribed by your health care professional. Use this drug for a condition that is listed in this section only if it has been so prescribed by your health care professional.
This vitamin may also be used with other vitamins for a certain eye condition (macular degeneration).
How to use Ascorbic acid (Zincovit Cap)Take this vitamin by mouth with or without food, usually 1 to 2 times daily. Follow all directions on the product package, or take as directed by your doctor.
If you are taking the extended-release capsules, swallow them whole. Do not crush or chew extended-release capsules or tablets. Doing so can release all of the drug at once, increasing the risk of side effects. Also, do not split extended-release tablets unless they have a score line and your doctor or pharmacist tells you to do so. Swallow the whole or split tablet without crushing or chewing. Take this product with a full glass of water (8 ounces/240 milliliters) unless your doctor directs you otherwise.
If you are taking the wafers or chewable tablets, chew them thoroughly and then swallow. If you are taking the lozenges, place the lozenge in your mouth and allow it to slowly dissolve.
If you are taking the powder, mix it thoroughly in the proper amount of liquid and stir well. Drink all of the liquid right away. Do not prepare a supply for future use. If you are using the liquid form of this vitamin, carefully measure the dose using a special measuring device/spoon. Do not use a household spoon because you may not get the correct dose.
Dosage is based on your medical condition and response to treatment.
Use this vitamin regularly to get the most benefit from it. To help you remember, take it at the same time(s) each day.
If you think you may have a serious medical problem, seek immediate medical attention.
There are specific as well as general uses of a drug or medicine. A medicine can be used to prevent a disease, treat a disease over a period or cure a disease. It can also be used to treat the particular symptom of the disease. The drug use depends on the form the patient takes it. It may be more useful in injection form or sometimes in tablet form. The drug can be used for a single troubling symptom or a life-threatening condition. While some medications can be stopped after few days, some drugs need to be continued for prolonged period to get the benefit from it.Biotin (Zincovit Cap) is a water soluble B-complex vitamin needed for normal growth and development of skin and hair and maintenance of a healthy nervous system and bone marrow. It is used to prevent and treat Biotin (Zincovit Cap) deficiency associated with pregnancy, long-term tube feeding, malnutrition, and rapid weight loss. It is also used orally for hair loss, brittle nails, skin rash in infants (seborrheic dermatitis), diabetes, and mild depression.
There are specific as well as general uses of a drug or medicine. A medicine can be used to prevent a disease, treat a disease over a period or cure a disease. It can also be used to treat the particular symptom of the disease. The drug use depends on the form the patient takes it. It may be more useful in injection form or sometimes in tablet form. The drug can be used for a single troubling symptom or a life-threatening condition. While some medications can be stopped after few days, some drugs need to be continued for prolonged period to get the benefit from it.This medication is used to prevent or treat low blood Calcium pantothenate (Zincovit Cap) levels in people who do not get enough Calcium pantothenate (Zincovit Cap) from their diets. It may be used to treat conditions caused by low Calcium pantothenate (Zincovit Cap) levels such as bone loss (osteoporosis), weak bones (osteomalacia/rickets), decreased activity of the parathyroid gland (hypoparathyroidism), and a certain muscle disease (latent tetany). It may also be used in certain patients to make sure they are getting enough Calcium pantothenate (Zincovit Cap) (e.g., women who are pregnant, nursing, or postmenopausal, people taking certain medications such as phenytoin, phenobarbital, or prednisone).
Calcium pantothenate (Zincovit Cap) plays a very important role in the body. It is necessary for normal functioning of nerves, cells, muscle, and bone. If there is not enough Calcium pantothenate (Zincovit Cap) in the blood, then the body will take Calcium pantothenate (Zincovit Cap) from bones, thereby weakening bones. Having the right amount of Calcium pantothenate (Zincovit Cap) is important for building and keeping strong bones.
How to use Calcium pantothenate (Zincovit Cap)Take this medication by mouth with food. If your product contains Calcium pantothenate (Zincovit Cap) citrate, then it may be taken with or without food. Follow all directions on the product package, or take as directed by your doctor. For best absorption, if your daily dose is more than 600 milligrams, then divide your dose and space it throughout the day. If you are uncertain about any of the information, consult your doctor or pharmacist.
If you are using the chewable product, chew it well before swallowing.
If you are using the effervescent tablet, allow the tablet to fully dissolve in a glass of water before drinking it. Do not chew or swallow the tablet whole.
If you are using the liquid product or powder, measure the medication with a dose-measuring spoon or device to make sure you get the correct dose. Do not use a household spoon. If the liquid product is a suspension, shake the bottle well before each dose.
Use this medication regularly to get the most benefit from it. To help you remember, take it at the same time(s) each day.
If your doctor has recommended that you follow a special diet, it is very important to follow the diet to get the most benefit from this medication and to prevent serious side effects. Do not take other supplements/vitamins unless ordered by your doctor.
If you think you may have a serious medical problem, seek immediate medical attention.
There are specific as well as general uses of a drug or medicine. A medicine can be used to prevent a disease, treat a disease over a period or cure a disease. It can also be used to treat the particular symptom of the disease. The drug use depends on the form the patient takes it. It may be more useful in injection form or sometimes in tablet form. The drug can be used for a single troubling symptom or a life-threatening condition. While some medications can be stopped after few days, some drugs need to be continued for prolonged period to get the benefit from it.How to use Cyanocobalamin (Zincovit Cap) nasalThere are specific as well as general uses of a drug or medicine. A medicine can be used to prevent a disease, treat a disease over a period or cure a disease. It can also be used to treat the particular symptom of the disease. The drug use depends on the form the patient takes it. It may be more useful in injection form or sometimes in tablet form. The drug can be used for a single troubling symptom or a life-threatening condition. While some medications can be stopped after few days, some drugs need to be continued for prolonged period to get the benefit from it.Folic acid (Zincovit Cap) is the man-made form of folate. Folate is a B-vitamin naturally found in some foods. It is needed to form healthy cells, especially red blood cells.
Folic acid (Zincovit Cap) supplements may come in different forms (such as L-methylfolate, levomefolate, methyltetrahydrofolate). They are used to treat or prevent low folate levels. Low folate levels can lead to certain types of anemia. Conditions that can cause low folate levels include poor diet, pregnancy, alcoholism, liver disease, certain stomach/intestinal problems, kidney dialysis, among others. Women of childbearing age should receive adequate amounts of Folic acid (Zincovit Cap) either through their diet or supplements to prevent infant spinal cord birth defects.
How to use Folic acid (Zincovit Cap)Take this product by mouth with or without food as directed by your doctor, usually once daily. If you are taking the over-the-counter product, follow all directions on the product package. If you have any questions, ask your doctor or pharmacist.
Dosage is based on your medical condition and response to treatment. Do not increase your dose or take this product more often than directed.
Take this product regularly to get the most benefit from it. To help you remember, take it at the same time each day. Follow the diet plan recommended by your doctor or dietician. See also Notes section.
If your condition persists or worsens, or if you think you may have a serious medical problem, get medical help right away.
There are specific as well as general uses of a drug or medicine. A medicine can be used to prevent a disease, treat a disease over a period or cure a disease. It can also be used to treat the particular symptom of the disease. The drug use depends on the form the patient takes it. It may be more useful in injection form or sometimes in tablet form. The drug can be used for a single troubling symptom or a life-threatening condition. While some medications can be stopped after few days, some drugs need to be continued for prolonged period to get the benefit from it.To treat Hartnup disease (light sensitive skin rashes), inflammatory skin disease, vitamin deficiency, anxiety and Alzheimer’s disease (disorder that causes mental confusion and forgetfulness). It is also used in combination with intravenous Niacinamide (Zincovit Cap) therapy for cancer.
There are specific as well as general uses of a drug or medicine. A medicine can be used to prevent a disease, treat a disease over a period or cure a disease. It can also be used to treat the particular symptom of the disease. The drug use depends on the form the patient takes it. It may be more useful in injection form or sometimes in tablet form. The drug can be used for a single troubling symptom or a life-threatening condition. While some medications can be stopped after few days, some drugs need to be continued for prolonged period to get the benefit from it.Use: Labeled IndicationsPyridoxine hydrochloride (Zincovit Cap) deficiency: Treatment and prevention of Pyridoxine hydrochloride (Zincovit Cap) (vitamin B) deficiency.
Off Label UsesEthylene glycol poisoning
The American Academy of Clinical Toxicology guidelines recognize the lack of human clinical data for this use and consider Pyridoxine hydrochloride (Zincovit Cap) as an adjunctive cofactor therapy in ethylene glycol poisoning without a formal or evidence-based recommendation, especially in patients who may have vitamin deficiencies (eg, patients with alcoholism). Additional data may be necessary to further define the role of Pyridoxine hydrochloride (Zincovit Cap) in this condition.
Peripheral neuropathy associated with isoniazid therapy for Mycobacterium tuberculosis (prevention)Based on the Department of Health and Human Services (DHHS) Guidelines for the Prevention and Treatment of Opportunistic Infections in HIV-Infected Adults and Adolescents, Pyridoxine hydrochloride (Zincovit Cap) is effective and recommended in the prevention of peripheral neuropathy associated with isoniazid therapy for Mycobacterium tuberculosis.
There are specific as well as general uses of a drug or medicine. A medicine can be used to prevent a disease, treat a disease over a period or cure a disease. It can also be used to treat the particular symptom of the disease. The drug use depends on the form the patient takes it. It may be more useful in injection form or sometimes in tablet form. The drug can be used for a single troubling symptom or a life-threatening condition. While some medications can be stopped after few days, some drugs need to be continued for prolonged period to get the benefit from it.Riboflavin (Zincovit Cap) (Riboflavin (Zincovit Cap)) supplementation is used to prevent and treat Riboflavin (Zincovit Cap) deficiency. Riboflavin (Zincovit Cap) may prevent migraine headaches at high doses and be useful for prevention of eye conditions such as cataract, glaucoma and tired eyes (fatigue). Riboflavin (Zincovit Cap) is also used for boosting of immune system, and maintenance of healthy hair, skin, nails and mucous membranes.
There are specific as well as general uses of a drug or medicine. A medicine can be used to prevent a disease, treat a disease over a period or cure a disease. It can also be used to treat the particular symptom of the disease. The drug use depends on the form the patient takes it. It may be more useful in injection form or sometimes in tablet form. The drug can be used for a single troubling symptom or a life-threatening condition. While some medications can be stopped after few days, some drugs need to be continued for prolonged period to get the benefit from it.Use: Labeled IndicationsTreatment and prevention of Vitamin A acetate (Zincovit Cap) deficiency; parenteral (IM) route is indicated when oral administration is not feasible or when absorption is insufficient (malabsorption syndrome); dietary supplement (OTC)
Off Label UsesXerophthalmia caused by Vitamin A acetate (Zincovit Cap) deficiency
Based on the World Health Organization (WHO) Model Formulary, Vitamin A acetate (Zincovit Cap) given for the treatment of xerophthalmia caused by Vitamin A acetate (Zincovit Cap) deficiency is effective and recommended in the management of this condition.
There are specific as well as general uses of a drug or medicine. A medicine can be used to prevent a disease, treat a disease over a period or cure a disease. It can also be used to treat the particular symptom of the disease. The drug use depends on the form the patient takes it. It may be more useful in injection form or sometimes in tablet form. The drug can be used for a single troubling symptom or a life-threatening condition. While some medications can be stopped after few days, some drugs need to be continued for prolonged period to get the benefit from it.Vitamin D (Zincovit Cap) (ergocalciferol-D2, cholecalciferol-D3, alfacalcidol) is a fat-soluble vitamin that helps your body absorb Vitamin D (Zincovit Cap) and phosphorus. Having the right amount of Vitamin D (Zincovit Cap), Vitamin D (Zincovit Cap), and phosphorus is important for building and keeping strong bones. Vitamin D (Zincovit Cap) is used to treat and prevent bone disorders (such as rickets, osteomalacia). Vitamin D (Zincovit Cap) is made by the body when skin is exposed to sunlight. Sunscreen, protective clothing, limited exposure to sunlight, dark skin, and age may prevent getting enough Vitamin D (Zincovit Cap) from the sun.
Vitamin D (Zincovit Cap) with Vitamin D (Zincovit Cap) is used to treat or prevent bone loss (osteoporosis). Vitamin D (Zincovit Cap) is also used with other medications to treat low levels of Vitamin D (Zincovit Cap) or phosphate caused by certain disorders (such as hypoparathyroidism, pseudohypoparathyroidism, familial hypophosphatemia). It may be used in kidney disease to keep Vitamin D (Zincovit Cap) levels normal and allow normal bone growth. Vitamin D (Zincovit Cap) drops (or other supplements) are given to breast-fed infants because breast milk usually has low levels of Vitamin D (Zincovit Cap).
How to use Vitamin D (Zincovit Cap)Take Vitamin D (Zincovit Cap) by mouth as directed. Vitamin D (Zincovit Cap) is best absorbed when taken after a meal but may be taken with or without food. Alfacalcidol is usually taken with food. Follow all directions on the product package. If you are uncertain about any of the information, consult your doctor or pharmacist.
If your doctor has prescribed this medication, take as directed by your doctor. Your dosage is based on your medical condition, amount of sun exposure, diet, age, and response to treatment.
Measure the liquid medication with the dropper provided, or use a medication-measuring spoon/device to make sure you have the correct dose. If you are taking the chewable tablet or wafers, chew the medication thoroughly before swallowing. Do not swallow whole wafers.
Certain medications (bile acid sequestrants such as cholestyramine/colestipol, mineral oil, orlistat) can decrease the absorption of Vitamin D (Zincovit Cap). Take your doses of these medications as far as possible from your doses of Vitamin D (Zincovit Cap) (at least 2 hours apart, longer if possible). It may be easiest to take Vitamin D (Zincovit Cap) at bedtime if you are also taking these other medications. Ask your doctor or pharmacist how long you should wait between doses and for help finding a dosing schedule that will work with all your medications.
Take this medication regularly to get the most benefit from it. To help you remember, take it at the same time each day if you are taking it once a day. If you are taking this medication only once a week, remember to take it on the same day each week. It may help to mark your calendar with a reminder.
If your doctor has recommended that you follow a special diet (such as a diet high in Vitamin D (Zincovit Cap)), it is very important to follow the diet to get the most benefit from this medication and to prevent serious side effects. Do not take other supplements/vitamins unless ordered by your doctor.
If you think you may have a serious medical problem, get medical help right away.
a. Use only in a suitable ISO Class 5 work area such as a laminar flow hood (or an equivalent clean air compounding area)
b. Penetrate each PBP vial closure only one time with a suitable sterile transfer device or dispensing set that allows measured dispensing of the contents. Given that pressure may develop within the vial during storage, excercise caution when withdrawing contents from the vial.
c. Once the closure system has been penetrated, complete all dispensing from the PBP vial within 4 hours. Each dose must be used immediately. Discard unused portion.
d. Prior to administration, Ascorbic acid (Zincovit Cap) must be diluted in a suitable infusion solution and the final solution for infusion must be isotonic (undiluted the osmolarity of Ascorbic acid (Zincovit Cap) is approximately 5,900 mOsmol/L). Prior to preparing the admixture for infusion, calculate the osmolarity of the intended admixture for infusion. Add one daily dose of Ascorbic acid (Zincovit Cap) directly to an appropriate volume of a suitable infusion solution (e.g., 5% Dextrose Injection, Sterile Water for Injection) and add appropriate solutes, as necessary, to make final solution isotonic. Sterile Water for Injection is highly hypotonic; adjust solute content, as necessary, to make thet final infusion solution isotonic prior to injection. Do not mix Ascorbic acid (Zincovit Cap) with solutions containing elemental compounds that can be reduced (e.g., copper). The concentration of Ascorbic acid (Zincovit Cap) in the final, admixture solution for infusion is to be the range of 1 to 25 mg of Ascorbic acid (Zincovit Cap) per mL. For example, for the largest recommended dose:
Add 200 mg of Ascorbic acid (Zincovit Cap) (equivalent to 0.4 mL of Ascorbic acid (Zincovit Cap)) to 7.5 mL of Sterile Water for Injection to produce an infusion solution having an approximate osmolarity of 290 mOsmol/L. In this specific example, addition of solute is NOT necessary because the solution is isotonic.
e. Prepare the recommended dose based on the patient population [ see Dosage and Administration (2.2), (2.3)].
f. Visually inspect for particulate matter and discoloration prior to administration (the diluted Ascorbic acid (Zincovit Cap) solution should appear colorless to pale yellow).
g. Immediately administer the admixture for infusion as a slow intravenous infusion [ see Recommended Dosage, (2.2)]
Recommended Dosage
Table 1 provides recommended doses of Ascorbic acid (Zincovit Cap) based on patient population and infusion rates of diluted Ascorbic acid (Zincovit Cap) solution.
The recommended maximum duration of daily treatment with Ascorbic acid (Zincovit Cap) is seven days. If no improvement in scorbutic symptoms is observed after one week of treatment, retreat until resolution of scorbutic symptoms is observed.
Repeat dosing is not recommended in pediatric patients less than 11 years of age.
Dosage Reductions in Specific Populations
Women who are pregnant or lactating and patients with glucose-6-dehydrogenase deficiency should not exceed the U.S. Recommended Dietary Allowance (RDA) or daily Adequate Intake (AI) level for Ascorbic acid (Zincovit Cap) for their age group and condition [ see Warnings and Precautions (5.2) and Use in Specific Populations (8.1, 8.2)].
Dosage FormsExcipient information presented when available (limited, particularly for generics); consult specific product labeling. [DSC] = Discontinued product
Capsule,
Oral:Meribin: 5 mg
Capsule,
Oral [preservative free]:Biotin (Zincovit Cap) Extra Strength: 10 mg [gluten free; contains soybean lecithin, soybean oil]
Generic: 5000 mcg
Tablet,
Oral:Generic: 1000 mcg, 5 mg, 10 mg
Tablet,
Oral [preservative free]:Generic: 300 mcg [DSC], 1000 mcg
Dosing: Adult
Dietary supplementation (OTC labeling):
Oral: UsualDosage: One tablet or capsule daily; also see specific product labeling
Dosing: Geriatric
Refer to adult dosing.
Dosing: Pediatric
Biotinidase deficiency, symptomatic: Limited data available: Infants, Children, and Adolescents:
Oral: 5 to 20 mg1 or 2 tabs daily.
The recommended initial dose of Cyanocobalamin (Zincovit Cap) (Cyanocobalamin (Zincovit Cap)) Nasal Spray is one spray (500 mcg) administered in ONE nostril once weekly. Cyanocobalamin (Zincovit Cap) (Cyanocobalamin (Zincovit Cap)) Nasal Spray should be administered at least one hour before or one hour after ingestion of hot foods or liquids. Periodic monitoring of serum B levels should be obtained to establish adequacy of therapy.
Priming (Activation) of PumpBefore the first dose and administration, the pump must be primed. Remove the clear plastic cover and the plastic safety clip from the pump. To prime the pump, place nozzle between the first and second finger with the thumb on the bottom of the bottle. Pump the unit firmly and quickly until the first appearance of spray. Then prime the pump an additional 2 times. Now the nasal spray is ready for use. The unit must be re-primed before each dose. Prime the pump once immediately before each administration of doses 2 through 8.
How suppliedCyanocobalamin (Zincovit Cap) (Cyanocobalamin (Zincovit Cap)) Nasal Spray is available as a spray in 3 mL glass bottles containing 2.3 mL of solution. It is available in a dosage strength of 500 mcg per actuation (0.1 mL/actuation). A screw-on actuator is provided. This actuator, following priming, will deliver 0.1 mL of the spray. Cyanocobalamin (Zincovit Cap) (Cyanocobalamin (Zincovit Cap)) Nasal Spray is provided in a carton containing a nasal spray actuator with dust cover, a bottle of nasal spray solution, and a package insert. One bottle will deliver 8 doses (NDC 67871-773-35).
Pharmacist Assembly Instructions For Cyanocobalamin (Zincovit Cap) (Cyanocobalamin (Zincovit Cap)) Nasal SprayThe pharmacist should assemble the Cyanocobalamin (Zincovit Cap) (Cyanocobalamin (Zincovit Cap)) Nasal Spray unit prior to dispensing to the patient, according to the following instructions:
Mfd. for QOL Medical, LLC
Kirland, WA 98033, USA
1.866.469.3773
www.Cyanocobalamin (Zincovit Cap) (Cyanocobalamin (Zincovit Cap)).com
3078 Rev. 02/06
FDA rev date: 9/15/2006
Usual Adult Dose for Megaloblastic Anemia1 mg orally, intramuscularly, subcutaneously or IV once a day. May continue until clinical symptoms of folate deficiency and the hematological profile have normalized.
Usual Adult Dose for Folic acid (Zincovit Cap) Deficiency
400 to 800 mcg orally, intramuscularly, subcutaneously or IV once a day.
Women of childbearing age, pregnant, and lactating women: 800 mcg orally, intramuscularly, subcutaneously or IV once a day.
Usual Pediatric Dose for Folic acid (Zincovit Cap) Deficiency
Infant:
0.1 mg orally, intramuscularly, subcutaneously or IV once a day.
Child:
Less than 4 years: up to 0.3 mg orally, intramuscularly, subcutaneously or IV once a day.
4 years or older: 0.4 mg orally, intramuscularly, subcutaneously or IV once a day.
Usual Pediatric Dose for Vitamin/Mineral Supplementation
Recommended daily allowance (RDA):
Premature neonates: 50 mcg/day (15 mcg/kg/day).
Full-term neonates and infants 1 to 6 months: 25 to 35 mcg/day.
Children:
1 to 3 years: 150 mcg/day.
4 to 8 years: 200 mcg/day.
9 to 13 years: 300 mcg/day.
14 years and older: 400 mcg/day.
Renal Dose Adjustments
Data not available
Liver Dose Adjustments
Data not available
Dose Adjustments
Rarely, a dosage of 2 mg/day may be required, particularly in patients with malabsorption, alcoholism, chronic hemolysis, chronic exfoliative skin disease or who are on concomitant anticonvulsant therapy.
Dialysis
Folic acid (Zincovit Cap) is removed by both hemodialysis and peritoneal dialysis. The amount removed varies with type equipment used.
Because folate may accumulate in patients with end-stage renal disease, side effects may be more likely in this patient who is undergoing dialysis. Once this patient's body stores of folate are replete, three times a week dosing may be just as beneficial as once daily dosing but should portend a lower risk of side effects.
Other Comments
The recommended daily allowance of Folic acid (Zincovit Cap) for adult males and females ranges from 150 to 200 and 150 to 180 mcg/day, respectively.
There is a potential danger in administering Folic acid (Zincovit Cap) to patients with undiagnosed anemia, since Folic acid (Zincovit Cap) may obscure the diagnosis of pernicious anemia by alleviating the hematologic manifestations of the disease while allowing the neurologic complications to progress.
Severe megaloblastic anemia may require therapy for 4 to 5 weeks. Once stabilized, if dietary intake is inadequate, maintenance therapy can be started.
Applies to the following strengths: 100 mg; 500 mg
Usual Adult Dose for:
Recommended Daily Allowances (RDA):
Males: 19 mg orally each day
Females: 13 mg orally each day
Initial dose: 100 mg orally 3 times a day, with or after meals
Maintenance dose: 100 to 500 mg orally up to 3 times a day, with or after meals
Niacinamide (Zincovit Cap) has toxic potential at adult doses in excess of 3 g/day.
Niacinamide (Zincovit Cap) may also be administered parenterally as a component of injectable multivitamin additives contained in parenteral nutrition products. All existing parenteral vitamin products for adults contain 40 mg/vial, which is the dose recommended by the American Medical Association/Nutrition Advisory Group for patients 11 years and older requiring parenteral vitamins.
Usual Adult Dose for Pemphigus
Recommended Daily Allowances (RDA):
Males: 19 mg orally each day
Females: 13 mg orally each day
Initial dose: 100 mg orally 3 times a day, with or after meals
Maintenance dose: 100 to 500 mg orally up to 3 times a day, with or after meals
Niacinamide (Zincovit Cap) has toxic potential at adult doses in excess of 3 g/day.
Niacinamide (Zincovit Cap) may also be administered parenterally as a component of injectable multivitamin additives contained in parenteral nutrition products. All existing parenteral vitamin products for adults contain 40 mg/vial, which is the dose recommended by the American Medical Association/Nutrition Advisory Group for patients 11 years and older requiring parenteral vitamins.
Usual Pediatric Dose for Niacin Deficiency
Recommended Daily Allowances (RDA):
0 to 6 months: 5 mg orally each day
6 months to 1 year: 6 mg orally each day
1 to 3 years: 9 mg orally each day
4 to 6 years: 12 mg orally each day
7 to 10 years: 13 mg orally each day
Males:
11 to 14 years: 17 mg orally each day
15 to 18 years: 20 mg orally each day
19 to 50 years: 19 mg orally each day
Females:
11 to 50 years: 13 mg orally each day
Niacinamide (Zincovit Cap) may also be administered parenterally as a component of injectable multivitamin additives contained in parenteral nutrition products. All existing parenteral vitamin products for children contain 17 mg/vial, which is the dose recommended by the American Medical Association/Nutrition Advisory Group for patients under 11 years of age.
Usual Pediatric Dose for Pemphigus
Recommended Daily Allowances (RDA):
0 to 6 months: 5 mg orally each day
6 months to 1 year: 6 mg orally each day
1 to 3 years: 9 mg orally each day
4 to 6 years: 12 mg orally each day
7 to 10 years: 13 mg orally each day
Males:
11 to 14 years: 17 mg orally each day
15 to 18 years: 20 mg orally each day
19 to 50 years: 19 mg orally each day
Females:
11 to 50 years: 13 mg orally each day
Niacinamide (Zincovit Cap) may also be administered parenterally as a component of injectable multivitamin additives contained in parenteral nutrition products. All existing parenteral vitamin products for children contain 17 mg/vial, which is the dose recommended by the American Medical Association/Nutrition Advisory Group for patients under 11 years of age.
Renal Dose Adjustments
Data not available
Liver Dose Adjustments
Because Niacinamide (Zincovit Cap) is primarily metabolized by the liver and because of the risk of hepatotoxicity, Niacinamide (Zincovit Cap) in not recommended in patients with liver dysfunction.
Dialysis
Data not available
Other Comments
Taking Niacinamide (Zincovit Cap) with food may reduce stomach upset.
Niacinamide (Zincovit Cap) should not be taken with hot drinks.
Further informationAlways consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Medical Disclaimer
More about Niacinamide (Zincovit Cap)
Usual Adult Dose for Drug Induced Vitamin/Mineral Deficiency:
Drug Induced Neuritis:
Cycloserine: 100 to 300 mg/day orally in divided doses.
Isoniazid or penicillamine: 100 to 200 mg/day orally for 3 weeks or 25 to 100 mg/day for prophylaxis.
Oral contraceptives: 25 to 30 mg/day orally.Acute Intoxication:
Hydralazine: 25 mg/kg. One-third of the dose should be administered IM and the remainder administered as an IV infusion over 3 hours.
Isoniazid: 1 to 4 grams IV as a first dose, then 1 g IM every 30 minutes until the total required dose has been administered (given with other anticonvulsants as needed). The total dose administered should equal the amount of isoniazid ingested.
Mushroom ingestion (genus Gyromitra): 25 mg/kg IV infused over 15 to 30 minutes. Repeat as needed to a maximum total daily dose of 15 to 20 g.
Usual Adult Dose for Dietary Supplement:
Pyridoxine hydrochloride (Zincovit Cap) Deficiency:
10 to 25 mg/day orally, IM, or IV for 3 weeks followed by 2 to 5 mg/day from a multivitamin product.
Usual Adult Dose for Anemia:
Sideroblastic, hereditary: 200 to 600 mg orally daily. If adequate response obtained, dose may be decreased to 30 to 50 mg orally daily.
If therapeutic response is not obtained after 1 to 2 months of Pyridoxine hydrochloride (Zincovit Cap) therapy, a different therapy should be considered.
Usual Adult Dose for Nausea/Vomiting:
Nausea and vomiting of Pregnancy:
25 mg orally every 8 hours.
Usual Pediatric Dose for Drug Induced Vitamin/Mineral Deficiency:
Drug Induced Neuritis (cycloserine, isoniazid, hydralazine, penicillamine) :
Treatment: 10 to 50 mg/day.
Prophylaxis: 1 to 2 mg/kg/day
Acute Intoxication:
Hydralazine: 25 mg/kg: One-third of the dose should be administered IM and the remainder administered as an IV infusion over 3 hours.
Isoniazid: Acute ingestion of known amount: Initial: A total dose of Pyridoxine hydrochloride (Zincovit Cap) equal to the amount of isoniazid ingested (maximum dose: 70 mg/kg, up to 5 g); administer at a rate of 0.5 to 1 g/minute until seizures stop or the maximum initial dose has been administered; may repeat every 5 to 10 minutes as needed to control persistent seizure activity and/or CNS toxicity. If seizures stop prior to the administration of the calculated initial dose, infuse the remaining Pyridoxine hydrochloride (Zincovit Cap) over 4 to 6 hours. Acute ingestion of unknown amount: Initial: 70 mg/kg (maximum dose: 5 g); administer at a rate of 0.5 to 1 g/minute; may repeat every 5 to 10 minutes as needed to control persistent seizure activity and/or CNS toxicity.
Mushroom ingestion (genus Gyromitra): 25 mg/kg IV. Repeat as needed up to a maximum total dose of 15 to 20 g.
Usual Pediatric Dose for Dietary Supplement:
Pyridoxine hydrochloride (Zincovit Cap) Deficiency:
5 to 25 mg/day orally, IM, or IV for 3 weeks followed by 1.5 to 2.5 mg/day from a multivitamin product.
Usual Pediatric Dose for Seizures:
Pyridoxine hydrochloride (Zincovit Cap)-dependent seizures:
10 to 100 mg PO, IM, or IV initially, followed by 2 to 100 mg orally daily.
Dosage FormsExcipient information presented when available (limited, particularly for generics); consult specific product labeling.
Capsule,
Oral:B-2-400: 400 mg
Generic: 50 mg
Tablet,
Oral:Generic: 25 mg, 50 mg, 100 mg
Dosing: Adult
Dietary supplement:
Oral: 100 mg once or twice dailyPrevention of migraine headache (off-label use):
Oral: 400 mg once daily (Rahimdel 2015; Schoenen 1998)Dosing: Geriatric
Refer to adult dosing.
Dosing: Pediatric
Dietary supplement: Infants, Children, and Adolescents: A multivitamin preparation is most commonly used for the provision of Riboflavin (Zincovit Cap) supplementation in pediatric patients; the use of a single-ingredient Riboflavin (Zincovit Cap) product as a daily supplement for the prevention of deficiency in pediatric patients is very rare. If single-ingredient Riboflavin (Zincovit Cap) supplement is necessary, consult product labeling for appropriateness of product in infants and young children in particular.
Migraine headache, prevention: Limited data available, efficacy results variable: Children ≥ 8 years and Adolescents:
Oral: 200 to 400 mg once daily; dosing based on a retrospective study of 41 patients (ages 8 to 18 years) who received 200 mg/day (n=21) or 400 mg/day (n=20) as prophylaxis for migraine and migraine-type headaches; results showed significant reduction in primary endpoint of frequency of headache attack; 68.4% of patients had a ≥50% decrease in headache frequency during treatment (Condò 2009). However, in a prospective, placebo-controlled study of 48 patients (ages 5 to 15 years), patients received 200 mg/day (n=27) or placebo (n=21) and in the treatment group (Riboflavin (Zincovit Cap)) no benefit compared to placebo for migraine frequency or intensity was observed; a high placebo responder rate was also reported (MacLennan 2008).
Usual Adult Dose for Vitamin A acetate (Zincovit Cap) DeficiencyInitial dose: 100,000 Units intramuscularly once a day for 3 days
Maintenance dose: 50,000 Units intramuscularly once a day for 2 weeks
Use: Treatment of Vitamin A acetate (Zincovit Cap) deficiency when oral administration is not feasible or not available (e.g. anorexia, nausea, vomiting, pre- or post-operative conditions, "Malabsorption Syndrome" with accompanying steatorrhea)
Usual Adult Dose for Vitamin/Mineral Supplementation
US Recommended Dietary Allowance (RDA):
Adult male: 900 mcg retinol activity equivalents (RAE) (3000 international units [IU])
Tolerable Upper Intake Level (UL): 3000 mcg RAE (10,000 IU)
Adult female: 700 mcg RAE (2330 IU)
UL: 3000 mcg RAE (10,000 IU)
Comments:
-The Vitamin A acetate (Zincovit Cap) RDA is given as mcg of retinol activity equivalents (RAE) to account for the different bioactivities of retinol and provitamin A carotenoids.
-The body converts all dietary Vitamin A acetate (Zincovit Cap) into retinol; 2 mcg of beta-carotene from dietary supplements is converted to 1 mcg of retinol.
-The tolerable upper intake level is the maximum daily intake that is unlikely to have adverse health effects.
Usual Pediatric Dose for Vitamin A acetate (Zincovit Cap) Deficiency
Infants (under 1 year): 7500 to 15,000 Units intramuscularly once a day
Duration of therapy: 10 days
1 to 8 years: 17,500 to 35,000 Units intramuscularly once a day
Duration of therapy: 10 days
Adult dose:
Initial dose: 100,000 Units intramuscularly once a day for 3 days
Maintenance dose: 50,000 Units intramuscularly once a day for 2 weeks
Use: Treatment of Vitamin A acetate (Zincovit Cap) deficiency when oral administration is not feasible or not available (e.g. anorexia, nausea, vomiting, pre- or post-operative conditions, "Malabsorption Syndrome" with accompanying steatorrhea)
Usual Pediatric Dose for Vitamin/Mineral Supplementation
US Recommended Dietary Allowance (RDA):
0 to 6 months: 400 mcg retinol activity equivalents (RAE) (1332 international units [IU])
Tolerable Upper Intake Level (UL): 600 mcg RAE (2000 IU)
7 to 12 months: 500 mcg RAE (1665 IU)
UL: 600 mcg RAE (2000 IU)
1 to 3 years: 300 mcg RAE (1000 IU)
UL: 900 mcg RAE (3000 IU)
4 to 8 years: 400 mcg RAE (1332 IU)
UL: 900 mcg RAE (3000 IU)
9 to 13 years: 600 mcg RAE (2000 IU)
UL: 1700 mcg RAE (5667 IU)
14 to 18 years, male: 900 mcg RAE (3000 IU)
UL: 2800 mcg RAE (9333 IU)
14 to 18 years, female: 700 mcg RAE (2330 IU)
UL: 2800 mcg RAE (9333 IU)
Comments:
-The Vitamin A acetate (Zincovit Cap) RDA is given as mcg of retinol activity equivalents (RAE) to account for the different bioactivities of retinol and provitamin A carotenoids.
-The body converts all dietary Vitamin A acetate (Zincovit Cap) into retinol; 2 mcg of beta-carotene from dietary supplements is converted to 1 mcg of retinol.
-The tolerable upper intake level is the maximum daily intake that is unlikely to have adverse health effects.
Renal Dose Adjustments
Data not available
Liver Dose Adjustments
Data not available
Dose Adjustments
US Recommended Dietary Allowance (RDA):
Pregnancy:
14 to 18 years: 750 mcg retinol activity equivalents (RAE) (2500 international units [IU])
UL: 2800 mcg RAE (9333 IU)
18 to 50 years: 770 mcg RAE (2564 IU)
UL: 3000 mcg RAE (10,000 IU)
Lactation:
14 to 18 years: 1200 mcg RAE (2564 IU)
UL: 2800 mcg RAE (9333 IU)
18 to 50 years: 1300 mcg RAE (4329 IU)
UL: 3000 mcg RAE (10,000 IU)
Comments:
-The Vitamin A acetate (Zincovit Cap) RDA is given as mcg of retinol activity equivalents (RAE) to account for the different bioactivities of retinol and provitamin A carotenoids.
-The body converts all dietary Vitamin A acetate (Zincovit Cap) into retinol; 2 mcg of beta-carotene from dietary supplements is converted to 1 mcg of retinol.
-The tolerable upper intake level is the maximum daily intake that is unlikely to have adverse health effects.
Precautions
CONTRAINDICATIONS:
-Administration of the intramuscular formulation intravenously
-Hypervitaminosis A
-Hypersensitivity to any of the ingredients
-The safety of doses exceeding 6000 units Vitamin A acetate (Zincovit Cap) in pregnancy has not been established. Use of high doses in pregnancy or patients who may become pregnant is contraindicated. Doses above the recommended dietary allowance (RDA) may cause fetal harm; fetal abnormalities (central nervous system, eye, and palate malformations) were seen in animal overdose models. If patients become pregnant, apprise them of potential fetal harms.
Consult WARNINGS section for additional precautions.
Dialysis
Data not available
Further informationAlways consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Medical Disclaimer
Dosage FormsExcipient information presented when available (limited, particularly for generics); consult specific product labeling. [DSC] = Discontinued product
Capsule,
Oral:D3-50: 1.25 MG (50000 UT) [dairy free, egg free, fish derivative free, gluten free, kosher certified, no artificial color(s), nut free, soy free, sugar free, wheat free, yeast free]
Vitamin D (Zincovit Cap): 1.25 MG (50000 UT) [contains fd&c yellow #10 (quinoline yellow), fd&c yellow #6 (sunset yellow), soybean oil]
Vitamin D (Zincovit Cap): 250 MCG (10000 UT) [contains fd&c yellow #10 aluminum lake, fd&c yellow #6 aluminum lake, gelatin (bovine)]
Vitamin D (Zincovit Cap): 625 MCG (25000 UT) [contains soybean oil]
Dialyvite Vitamin D (Zincovit Cap) 5000: 125 MCG (5000 UT)
Pronutrients Vitamin D3: 25 MCG (1000 UT) [contains soybean oil]
Weekly-D: 1.25 MG (50000 UT) [contains fd&c red #40]
Generic: 1.25 MG (50000 UT), 250 MCG (10000 UT)
Capsule,
Oral [preservative free]:Vitamin D (Zincovit Cap): 125 MCG (5000 UT) [dairy free, dye free, egg free, gluten free, no artificial color(s), nut free, soy free, sugar free, wheat free, yeast free]
D3-50: 1.25 MG (50000 UT) [dairy free, egg free, fish derivative free, gluten free, kosher certified, no artificial color(s), nut free, soy free, sugar free, wheat free, yeast free]
Generic: 10,000 units, 125 MCG (5000 UT), 25 MCG (1000 UT), 50 MCG (2000 UT)
Liquid,
Oral:Aqueous Vitamin D (Zincovit Cap): 10 mcg/mL (50 mL) [gluten free, lactose free, sugar free; contains corn oil, methylparaben, polysorbate 80]
Bio-D-Mulsion: 10 mcg/0.03 mL (30 mL [DSC]) [contains sesame oil]
Bio-D-Mulsion Forte: 50 mcg/0.03 mL (30 mL [DSC]) [contains sesame oil]
BProtected Pedia D-Vite: 10 mcg/mL (50 mL) [alcohol free, sugar free; contains polysorbate 80, propylene glycol, sodium benzoate; cherry flavor]
Vitamin D (Zincovit Cap): 10 mcg/mL (50 mL) [gluten free, lactose free, sugar free; contains polysorbate 80]
D-Vita: 10 mcg/mL (50 mL [DSC]) [alcohol free, gluten free, lactose free, sugar free; contains polysorbate 80, propylene glycol, sodium benzoate; fruit flavor]
D-Vite Pediatric: 10 mcg/mL (50 mL) [alcohol free, gluten free, lactose free, no artificial color(s), sugar free; contains disodium edta, polysorbate 80, propylene glycol, saccharin sodium, sodium benzoate]
D3 Vitamin: 10 mcg/mL (50 mL) [contains polysorbate 80, sodium benzoate]
Generic: 10 mcg/mL (50 mL, 52 mL)
Liquid,
Oral [preservative free]:Generic: 125 mcg/mL (52 mL)
Liquid, Sublingual:
Generic: 5000 units/mL (60 mL)
Tablet,
Oral:Delta D3: 10 MCG (400 UNIT) [gelatin free, gluten free, lactose free, no artificial color(s), no artificial flavor(s), starch free, sugar free, yeast free]
Dialyvite Vitamin D3 Max: 1.25 MG (50000 UT) [scored]
Vitamin D3 Super Strength: 50 MCG (2000 UT) [gluten free]
Vitamin D3 Ultra Potency: 1.25 MG (50000 UT)
Generic: 10 MCG (400 UNIT), 125 MCG (5000 UT), 20 MCG (800 UNIT), 25 MCG (1000 UT), 50 MCG (2000 UT), 75 MCG (3000 UT)
Tablet,
Oral [preservative free]:Generic: 5000 units, 10 MCG (400 UNIT), 25 MCG (1000 UT), 50 MCG (2000 UT)
Tablet Chewable,
Oral:Generic: 10 MCG (400 UNIT)
Tablet Chewable,
Oral [preservative free]:Generic: 50 MCG (2000 UT)
Dosing: Adult
Note: 1 mcg = 40 units
Hypoparathyroidism (off-label use): Note: Active Vitamin D (Zincovit Cap) preparations (ie, alfacalcidol, calcitriol) in conjunction with Vitamin D (Zincovit Cap) supplementation are recommended therapy. Addition of cholecalciferol (or ergocalciferol) may be considered for supplemental therapy (Endocrine Society [Brandi 2016]).
Osteoporosis, prevention (off-label use): Adults ≥50 years of age:
Oral: 800 to 1,000 units/day is recommended, through dietary sources and/or supplementation if needed (NOF [Cosman 2014]).
Vitamin D (Zincovit Cap) insufficiency/deficiency treatment (off-label use): Note: Repletion strategies may vary depending on desired target serum 25(OH)D levels as well as the clinical status of the patient. The optimal serum 25(OH)D level is controversial; the Institute of Medicine recommends a 25(OH)D level >20 ng/mL as sufficient in nearly all persons (IOM 2011), whereas others have suggested targeting a level of ~30 ng/mL to minimize the risk of fractures, particularly in patients with osteoporosis (AACE [Camacho 2016]; NOF [Cosman 2014]). However, some data suggest levels >40 ng/mL (median level in one trial: ~48 ng/mL) are associated with increased risk of falls in postmenopausal women (Sanders 2010; Smith 2017).
Therefore, some experts recommend a range of 20 to 40 ng/mL as a reasonable target in most patients (Dawson-Hughes 2018). In patients with normal absorption, for every 100 units/day of cholecalciferol, the serum 25(OH)D level is expected to increase by ~0.7 to 1 ng/mL after a few weeks (ASPEN [McKeever 2017]; Dawson-Hughes 2018). The dose-response declines as the 25(OH)D concentration increases above 40 ng/mL (100 nmol/L) (Dawson-Hughes 2018). The following recommendations are based primarily on expert opinion and clinical experience:
Initial dosing (according to baseline serum 25(OH)D level):
Serum 25(OH)D 20 to 30 ng/mL: Initial: Supplementation dosing:
Oral: 600 to 800 units once daily; a repeat serum 25(OH)D level is not required (Dawson-Hughes 2018) or 1,000 to 2,000 units once daily; may consider a repeat serum 25(OH)D level in ~3 months to determine if the target level has been achieved (Khan 2010).
Serum 25(OH)D 10 to <20 ng/mL: Initial:
Supplementation dosing:
Oral: 800 to 1,000 units once daily (Dawson-Hughes 2018) orOR
Therapeutic dosing (ie, high-dose cholecalciferol):
Oral: 50,000 units once weeklydailySerum 25(OH)D <10 ng/mL or in patients with deficiency symptoms: Initial: Therapeutic dosing (ie, high-dose cholecalciferol):
Oral: 50,000 units once weeklydailyMaintenance dosing: Maintenance dosing is highly patient specific and dependent on target 25(OH)D level, and may range from: 600 to 800 units/day (Dawson-Hughes 2018) to 1,000 to 2,000 units/day (AACE [Camacho 2016]; NOF [Cosman 2014]).
Special populations (obese patients, patients on medications known to affect Vitamin D (Zincovit Cap) metabolism, patients with malabsorption syndromes or gastrectomy): Higher doses or longer durations may be necessary for adequate repletion (AACE [Camacho 2016]; Dawson-Hughes 2018).
Vitamin D (Zincovit Cap) deficiency/insufficiency in patients with chronic kidney disease (off-label use):
Oral:Note: In patients without severe and progressive hyperparathyroidism, including chronic kidney disease stages G3 to G5 and dialysis or transplant patients, KDIGO guidelines recommend correcting Vitamin D (Zincovit Cap) deficiency and insufficiency with treatment strategies recommended for the general population using cholecalciferol (or ergocalciferol) while avoiding hypercalcemia and ensuring phosphate levels are in the normal range. An individualized monitoring approach to direct treatment is also recommended (KDIGO 2009; KDIGO 2017). In patients in whom serum parathyroid hormone levels are progressively rising and remain persistently elevated despite correction of modifiable factors (eg, hyperphosphatemia, Vitamin D (Zincovit Cap) deficiency), calcitriol or Vitamin D (Zincovit Cap) analogs are suggested instead of cholecalciferol (or ergocalciferol) (KDOQI commentary [Uhlig 2010]).
Dosing: Geriatric
Refer to adult dosing.
Dosing: Pediatric
Vitamin D (Zincovit Cap) deficiency, prevention (eg, Rickets prevention): (AAP [Folsom 2017]; AAP [Wagner 2008]; Munns 2016):
Oral:Breast-fed infants (fully or partially):
Oral: 400 units/day beginning in the first few days of life. Continue supplementation until infant is weaned to ≥1,000 mL/day or 1 qt/day of Vitamin D (Zincovit Cap)-fortified formula or whole milk (after 12 months of age)
Formula-fed infants ingesting <1,000 mL of Vitamin D (Zincovit Cap)-fortified formula:
Oral: 400 units/dayChildren and Adolescents without adequate intake:
Oral: 400 to 600 units/day. Note:Vitamin D (Zincovit Cap) deficiency, treatment:
Oral: Note:Infants:
Oral: 2,000 units daily for 6 weeks to achieve a serum 25(OH)D level >20 ng/mL; followed by a maintenance dose of 400 to 1,000 units daily. Note: For patients at high risk of fractures a serum 25(OH)D level >30 ng/mL has been suggested (AAP [Golden 2014]).
Children and Adolescents:
Oral: 2,000 units daily for 6 to 8 weeks to achieve serum 25(OH)D level >20 ng/mL; followed by a maintenance dose of 600 to 1,000 units daily. Note: For patients at high risk of fractures a serum 25(OH)D level >30 ng/mL has been suggested (AAP [Golden 2014]).
Vitamin D (Zincovit Cap) deficiency in cystic fibrosis, prevention and treatment:
Oral:CF guidelines (Tangricha [CF Foundation] 2012):
Recommended initial daily intake to maintain serum 25(OH)D level ≥30 ng/mL:
Infants:
Oral: 400 to 500 units/dayChildren ≤10 years:
Oral: 800 to 1,000 units/dayChildren >10 years and Adolescents:
Oral: 800 to 2,000 units/dayDosing adjustment for serum 25(OH)D level between 20 to 30 ng/mL and patient adherence established (Step 1 increase):
Infants:
Oral: 800 to 1,000 units/dayChildren ≤10 years:
Oral: 1,600 to 3,000 units/dayChildren >10 years and Adolescents:
Oral: 1,600 to 6,000 units/dayDosing adjustment for serum 25(OH)D level <20 ng/mL or persistently between 20 to 30 ng/mL and patient adherence established (Step 2 increase):
Infants: Increase up to a maximum 2,000 units/day
Children ≤10 years: Increase to a maximum of 4,000 units/day
Children >10 years and Adolescents: Increase to a maximum of 10,000 units/day
Alternate dosing (Hall 2010):
Initial dose: Serum 25(OH)D level ≤30 ng/mL
Infants:
Oral: 8,000 units/weekChildren and Adolescents:
Oral: 800 units/dayMedium-dose regimen: Serum 25(OH)D level remains ≤30 ng/mL and patient compliance established
Infants and Children <5 years:
Oral: 12,000 units/week for 12 weeksChildren ≥5 years and Adolescents:
Oral: 50,000 units/week for 12 weeksHigh-dose regimen: Repeat 25(OH)D level remains ≤30 ng/mL and patient compliance established
Infants and Children <5 years:
Oral: 12,000 units twice weekly for 12 weeksChildren ≥5 years and Adolescents:
Oral: 50,000 units twice weekly for 12 weeksVitamin D (Zincovit Cap) insufficiency or deficiency associated with CKD (stages 2 to 5, 5D), treatment; serum 25 hydroxyvitamin D [25(OH)D] level ≤30 ng/mL (KDOQI Guidelines 2009):
Oral:Serum 25(OH)D level 16 to 30 ng/mL: Infants, Children, and Adolescents: 2,000 units/day for 3 months or 50,000 units every month for 3 months
Serum 25(OH)D level 5 to 15 ng/mL: Infants, Children, and Adolescents: 4,000 units/day for 12 weeks or 50,000 units every other week for 12 weeks
Serum 25(OH)D level <5 ng/mL: Infants, Children, and Adolescents: 8,000 units/day for 4 weeks then 4,000 units/day for 2 months for total therapy of 3 months or 50,000 units/week for 4 weeks followed by 50,000 units 2 times/month for a total therapy of 3 months
Maintenance dose [once repletion accomplished; serum 25(OH)D level >30 ng/mL]: Infants, Children, and Adolescents: 200 to 1,000 units/day
Nutritional rickets, treatment: Limited data available (Munns 2016): Administer in combination with Vitamin D (Zincovit Cap) supplementation:
Daily therapy (preferred):
Infants:
Oral: 2,000 units daily for ≥3 months, followed by maintenance dose of 400 units daily
Children:
Oral: 3,000 to 6,000 units daily for ≥3 months, followed by maintenance dose of 600 units daily
Adolescents:
Oral: 6,000 units daily for ≥3 months, followed by maintenance dose of 600 units daily
Single-dose therapy:
Infants ≥3 months:
Oral: 50,000 units once, or in divided doses over several days; after 3 months, initiate maintenance dose of 400 units daily
Children:
Oral: 150,000 units once, or in divided doses over several days; after 3 months, initiate maintenance dose of 600 units daily
Adolescents:
Oral: 300,000 units once, or in divided doses over several days; after 3 months, initiate maintenance dose of 600 units daily
See also:
What other drugs will affect Ascorbic acid (Zincovit Cap)?
In an application with barbiturates, primidone increases the excretion of Ascorbic acid (Zincovit Cap) in the urine.
With the simultaneous use of oral contraceptives reduces the concentration of Ascorbic acid (Zincovit Cap) in blood plasma.
In an application of Rhea Ascorbic acid (Zincovit Cap) with iron preparations Ascorbic acid (Zincovit Cap), due to its regenerative properties, transforms ferric iron in the bivalent, which improves its absorption.
Ascorbic acid (Zincovit Cap) in high doses can decrease urine pH that while the application reduces the tubular reabsorption of amphetamine and tricyclic antidepressants.
With the simultaneous use of aspirin reduces the absorption of Ascorbic acid (Zincovit Cap) by about a third.
Rhea Ascorbic acid (Zincovit Cap) in an application with warfarin may decrease effects of warfarin.
With the simultaneous application of Ascorbic acid (Zincovit Cap) increases the excretion of iron in patients receiving deferoxamine. In the application of Ascorbic acid (Zincovit Cap) at a dose of 500 mg / day possibly left ventricular dysfunction.
In an application with tetracycline is increased excretion of Ascorbic acid (Zincovit Cap) in the urine.
There is a described case of reducing the concentration of fluphenazine in plasma in patients treated with Ascorbic acid (Zincovit Cap) 500 mg 2 times / day.
May increase the concentration of ethinyl estradiol in the blood plasma in its simultaneous application in the oral contraceptives.
See also:
What other drugs will affect Biotin (Zincovit Cap)?
The anticonvulsants carbamazepine, phenytoin, Phenobarbital, and primidone may accelerate Biotin (Zincovit Cap) metabolism, leading to a reduction in available Biotin (Zincovit Cap). Chronic use of these drugs has been associated with decreased plasma concentrations of Biotin (Zincovit Cap).
The use of antibiotics may reduce the contribution of Biotin (Zincovit Cap) made by bacteria within the large intestine.
Dextropanthenyl alcohol in combination with hydrocortisone may be more effective than topical hydrocortisone alone in some dermatoses.
See also:
What other drugs will affect Cyanocobalamin (Zincovit Cap)?
The effects of some drugs can change if you take other drugs or herbal products at the same time. This can increase your risk for serious side effects or may cause your medications not to work correctly. These drug interactions are possible, but do not always occur. Your doctor or pharmacist can often prevent or manage interactions by changing how you use your medications or by close monitoring.
To help your doctor and pharmacist give you the best care, be sure to tell your doctor and pharmacist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products) before starting treatment with this product. While using this product, do not start, stop, or change the dosage of any other medicines you are using without your doctor's approval.
Some products that may interact with this drug include: drugs that affect the bone marrow (such as chloramphenicol), vitamins/supplements that contain intrinsic factor.
Certain medications can decrease the absorption of vitamin B12, including: colchicine, metformin, extended-release potassium products, antibiotics (such as gentamicin, neomycin, tobramycin), anti-seizure medications (such as phenobarbital, phenytoin, primidone), medications to treat heartburn (such as H2 blockers including cimetidine/famotidine, proton pump inhibitors such as omeprazole/lansoprazole).
Vitamin B12 is an ingredient found in many combination vitamin and nutritional products. Tell your doctor or pharmacist if you are taking other products that contain Cyanocobalamin (Zincovit Cap), vitamin B12, or hydroxocobalamin.
Cyanocobalamin (Zincovit Cap) may interfere with certain laboratory tests (including intrinsic factor, blood tests for other types of anemia), possibly causing false test results. Make sure laboratory personnel and all your doctors know you use this drug.
Certain drugs may interfere with laboratory tests for vitamin B12 levels, possibly causing false results. Tell laboratory personnel and all your doctors if you take any of the following: antibiotics (such as amoxicillin, erythromycin), methotrexate, pyrimethamine.
This document does not contain all possible drug interactions. Keep a list of all the products you use. Share this list with your doctor and pharmacist to lessen your risk for serious medication problems.
See also:
What other drugs will affect Folic acid (Zincovit Cap)?
Medications that interfere with your bodys ability to use folate may also increase the need for this vitamin. Medications can interfere with folate utilization, including: anticonvulsant medications (such as phenytoin, and primidone) metformin (sometimes prescribed to control blood sugar in type 2 diabetes) sulfasalazine (used to control inflammation associated with Crohns disease and ulcerative colitis) triamterene (a diuretic) Methotrexate There has been concern about the interaction between vitamin B12 and Folic acid (Zincovit Cap). Folic acid (Zincovit Cap) supplements can correct the anemia associated with vitamin B12 deficiency. Unfortunately, Folic acid (Zincovit Cap) will not correct changes in the nervous system that result from vitamin B12 deficiency. Permanent nerve damage could theoretically occur if vitamin B12 deficiency is not treated. Therefore, intake of supplemental Folic acid (Zincovit Cap) should not exceed 1000 micrograms (g, sometimes mcg) per day to prevent Folic acid (Zincovit Cap) from masking symptoms of vitamin B12 deficiency. It is important for older adults to be aware of the relationship between Folic acid (Zincovit Cap) and vitamin B12 because they are at greater risk of having a vitamin B12 deficiency. If you are 50 years of age or older, ask your physician to check your B12 status before you take a supplement that contains Folic acid (Zincovit Cap).
See also:
What other drugs will affect Pyridoxine hydrochloride (Zincovit Cap)?
Cycloserine, isoniazid, hydralazine, oral contraceptives, penicillamine
Increased need for Pyridoxine hydrochloride (Zincovit Cap).
Levodopa
Decreased effect of levodopa. (Interaction does not occur with levodopa/carbidopa in combination with Pyridoxine hydrochloride (Zincovit Cap).)
Phenytoin
Phenytoin serum levels may be decreased.
Incompatibility
Incompatible with alkaline solutions, iron salts and oxidizing agents (parenteral).
Laboratory Test Interactions
May result in false-positive urobilinogen in the spot test using Ehrlich reagent.
See also:
What other drugs will affect Riboflavin (Zincovit Cap)?
Interactions for Riboflavin (Zincovit Cap) (Riboflavin (Zincovit Cap))
Alcohol - impairs the intestinal absorption of riboflavi
Antidepressants (tricyclics or phenothiazines) - requirements for Riboflavin (Zincovit Cap) may be increased in patients receiving these medications
Probenecid - concurrent use decreases gastrointestinal absorption of Riboflavin (Zincovit Cap); requirements for Riboflavin (Zincovit Cap) may be increased in patients receiving probenecid.
none known
See also:
What other drugs will affect Vitamin A acetate (Zincovit Cap)?
Bexarotene (Topical): Vitamin A acetate (Zincovit Cap) may enhance the adverse/toxic effect of Bexarotene (Topical). Management: Limit doses of Vitamin A acetate (Zincovit Cap) to 5,000 units per day if combined with topical bexarotene. Consider therapy modification
Orlistat: May decrease the serum concentration of Vitamins (Fat Soluble). Management: Administer oral fat soluble vitamins at least 2 hours before or after the administration of orlistat. Similar precautions do not apply to parenterally administered fat soluble vitamins. Consider therapy modification
Retinoic Acid Derivatives: Vitamin A acetate (Zincovit Cap) may enhance the adverse/toxic effect of Retinoic Acid Derivatives. Exceptions: Adapalene; Alitretinoin (Topical); Bexarotene (Topical); Tretinoin (Topical). Avoid combination
See also:
What other drugs will affect Vitamin D (Zincovit Cap)?
Aluminum Hydroxide: Vitamin D (Zincovit Cap) Analogs may increase the serum concentration of Aluminum Hydroxide. Specifically, the absorption of aluminum may be increased, leading to increased serum aluminum concentrations. Avoid combination
Bile Acid Sequestrants: May decrease the serum concentration of Vitamin D (Zincovit Cap) Analogs. More specifically, bile acid sequestrants may impair absorption of Vitamin D (Zincovit Cap) Analogs. Management: Avoid concomitant administration of Vitamin D (Zincovit Cap) analogs and bile acid sequestrants (eg, cholestyramine). Separate administration of these agents by several hours to minimize the potential risk of interaction. Monitor plasma Vitamin D (Zincovit Cap) concentrations. Consider therapy modification
Vitamin D (Zincovit Cap) Salts: May enhance the adverse/toxic effect of Vitamin D (Zincovit Cap) Analogs. Monitor therapy
Cardiac Glycosides: Vitamin D (Zincovit Cap) Analogs may enhance the arrhythmogenic effect of Cardiac Glycosides. Monitor therapy
Danazol: May enhance the hypercalcemic effect of Vitamin D (Zincovit Cap) Analogs. Monitor therapy
Erdafitinib: Serum Phosphate Level-Altering Agents may diminish the therapeutic effect of Erdafitinib. Management: Avoid coadministration of serum phosphate level-altering agents with erdafitinib before initial dose increase period based on serum phosphate levels (Days 14 to 21). Consider therapy modification
Mineral Oil: May decrease the serum concentration of Vitamin D (Zincovit Cap) Analogs. More specifically, mineral oil may interfere with the absorption of Vitamin D (Zincovit Cap) Analogs. Management: Avoid concomitant, oral administration of mineral oil and Vitamin D (Zincovit Cap) analogs. Consider separating the administration of these agents by several hours to minimize the risk of interaction. Monitor plasma Vitamin D (Zincovit Cap) concentrations. Consider therapy modification
Multivitamins/Fluoride (with ADE): May enhance the adverse/toxic effect of Vitamin D (Zincovit Cap) Analogs. Avoid combination
Multivitamins/Minerals (with ADEK, Folate, Iron): May enhance the adverse/toxic effect of Vitamin D (Zincovit Cap) Analogs. Avoid combination
Orlistat: May decrease the serum concentration of Vitamin D (Zincovit Cap) Analogs. More specifically, orlistat may impair absorption of Vitamin D (Zincovit Cap) Analogs. Management: Monitor clinical response (including serum Vitamin D (Zincovit Cap)) to oral Vitamin D (Zincovit Cap) analogs closely if used with orlistat. If this combination must be used, consider giving the Vitamin D (Zincovit Cap) analog at least 2 hrs before or after orlistat. Consider therapy modification
Sucralfate: Vitamin D (Zincovit Cap) Analogs may increase the serum concentration of Sucralfate. Specifically, the absorption of aluminum from sucralfate may be increased, leading to an increase in the serum aluminum concentration. Avoid combination
Thiazide and Thiazide-Like Diuretics: May enhance the hypercalcemic effect of Vitamin D (Zincovit Cap) Analogs. Monitor therapy
Vitamin D (Zincovit Cap) Analogs: May enhance the adverse/toxic effect of other Vitamin D (Zincovit Cap) Analogs. Avoid combination
