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Zestril

Marketed in 33 countries across Europe, the Americas, Asia, and North Africa, Zestril is a globally distributed brand of lisinopril, classified within the group of agents acting on the renin-angiotensin system. For an international reader, that wide footprint matters: Zestril is one of the brands most likely to be recognised at a pharmacy counter abroad, even if the local equivalent ends up being a generic version of the same molecule.

Lisinopril is prescribed in the management of hypertension, heart failure, and the cardiovascular care of patients after a heart attack, as well as in the protection of kidney function in diabetes-related nephropathy. The structured indication block further down this page lists each registered use as recognised by the regulators in the markets where Zestril is sold, and reflects the medication's combined antihypertensive, vasodilator, cardioprotective, and nephroprotective profile.

Travellers and expatriates frequently encounter lisinopril abroad — sometimes labelled as Zestril, sometimes under another brand name, and very often as a generic. Markets where the brand is registered include Japan, Brazil, France, Canada, and Indonesia, but packaging, naming conventions, and prescription pathways vary considerably from one country to another. A pharmacist in the destination country can usually confirm whether a locally available lisinopril product corresponds to what the patient was previously taking.

Other medications acting on the renin-angiotensin system are also distributed widely under different molecules and brand names, and they are not freely interchangeable. Anyone taking Zestril regularly, considering it, or trying to identify a local equivalent should treat any change as a clinical decision and discuss it with a healthcare provider familiar with their full medical history.

Countries
Argentina Australia Bangladesh Belgium Brazil Canada China Egypt France Greece Hong Kong Indonesia Ireland Italy Japan Lebanon Malaysia Malta Mexico Netherlands Norway Oman Peru Philippines Portugal South Africa Spain Sweden Switzerland Taiwan United Kingdom USA Vietnam
Diseases
Hypertension Diabetic Kidney Disease Diabetes Mellitus Heart Failure Heart Attack Type 2 Diabetes Nephropathy
Ingredients
Lisinopril
Drug Actions
Agents acting in the renin-angiotensin system Antihypertensive Hypotensive Vasodilator Cardioprotective Natriuretic Nephroprotective

Drugs with the same active ingredients

Doxapril Lisinal Tensopril Tensopril (lisinopril) Tensopril d Tersif md Agimlisin Co-trupril Lisinopril generic health Lisinopril ranbaxy Lisinopril sandoz Lisinopril-ga Zinopril Ecamais Laaven Laaven-hd Laaven-hl Nafordyl Qbrelis Qbrelis (oral)

Shelf life

4 years.

Incompatibilities

Not applicable.

List of excipients

Mannitol

Calcium Hydrogen Phosphate dihydrate

Red Iron Oxide (E172)

Maize Starch

Pregelatinised Starch

Magnesium Stearate

Date of revision of the text

5th October 2017

Marketing authorisation holder

AstraZeneca UK Limited,

600 Capability Green,

Luton, LU1 3LU, UK.

Special precautions for storage

Do not store above 30°C

Nature and contents of container

5 mg Tablets:

Aluminium/PVC-PVDC or Aluminium/PVC foil blister packs of 14, 20, 28, 28x1, 30, 42, 50, 56, 60, 84, 98, 100, 400 and 500 tablets.

Aluminium/PVC-PVDC or Aluminium/PVC foil blister calendar packs of 14, 28, 42, 56, 84 and 98 tablets.

HDPE bottle packs of 20, 30, 50, 100 and 400 tablets.

10 mg Tablets:

Aluminium/PVC-PVDC or Aluminium/PVC foil blister packs of 14, 20, 28, 30, 50, 56, 84, 98, 100 and 400 tablets.

Aluminium/PVC-PVDC or Aluminium/PVC foil blister calendar packs of 14, 28, 56, 84 and 98 tablets.

HDPE bottle packs of 20, 30, 50, 100 and 400 tablets.

20 mg Tablets:

Aluminium/PVC-PVDC or Aluminium/PVC foil blister packs of 14, 20, 28, 30, 42, 50, 56, 56x1, 60, 84, 98, 100, 400 and 500 tablets.

Aluminium/PVC-PVDC or Aluminium/PVC foil blister calendar packs of 14, 28, 42, 56, 84 and 98 tablets.

HDPE bottle packs of 20, 30, 50, 100 and 400 tablets.

Not all pack sizes may be marketed.

Marketing authorisation number(s)

5 mg:

PL 17901/0061

10 mg:

PL 17901/0062

20 mg:

PL 17901/0063

Special precautions for disposal and other handling

No special requirements.

Date of first authorisation/renewal of the authorisation

Date of first authorisation: 8 June 2000

Date of first renewal: 1 August 2010

Frequently asked questions

What conditions does Zestril treat?

Zestril is prescribed in the management of hypertension, heart failure, and the cardiovascular care of patients following a heart attack. It is also used in the protection of kidney function in patients with diabetic nephropathy and related conditions associated with type 2 diabetes. As an agent acting on the renin-angiotensin system, it carries antihypertensive, vasodilator, and nephroprotective properties. The structured indication block below this introduction details each registered use.

What is the active ingredient in Zestril?

Zestril contains lisinopril, classified among agents acting on the renin-angiotensin system. Lisinopril is the same molecule whether sold under the Zestril brand or as a generic — internationally, the same active ingredient circulates under a number of commercial names, particularly in markets where the original patent has long expired and several manufacturers produce lisinopril-containing products in parallel.

In how many countries is Zestril available?

Zestril carries marketing authorisation in 33 countries spanning several regions, including Japan, Brazil, France, Canada, Egypt, Indonesia, and Australia. The brand has a broad international presence but is not registered everywhere. If your country is not represented on this list, a local pharmacist can usually confirm whether lisinopril is available in that market under a different brand name or as a generic equivalent.

Are there other medications with the same active ingredient as Zestril?

Lisinopril is sold under several brand names worldwide, particularly as generics in markets where the original patent has expired. Other medications acting on the renin-angiotensin system also exist, although they are not interchangeable without medical guidance — molecules within this category can have meaningfully different profiles. To identify a local lisinopril-containing product, search the active ingredient on Pill2Trip or ask a pharmacist in your country.

Is Zestril a prescription medication?

Zestril is a prescription medication in essentially every country where it is registered, and therapy with agents acting on the renin-angiotensin system is calibrated to a patient's full cardiovascular and renal profile. This matters especially for travellers and people relocating between countries, as prescription rules, available generics, and brand names vary across regulatory systems. Any decision to start, stop, or substitute lisinopril should be made together with a healthcare provider.

Zestril

Available in 33 countries