See also:
What is the most important information I should know about Hydroquinone (White UP)?
Before using Hydroquinone (White UP) topical, tell your doctor if you are allergic to any drugs, or if you have liver or kidney disease.
Do not use Hydroquinone (White UP) topical on skin that is sunburned, windburned, dry, chapped, or irritated, or on an open wound. It could make these conditions worse. Wait until these conditions have healed before applying Hydroquinone (White UP) topical.
Avoid getting this medication in your mouth or eyes. If it does get into any of these areas, rinse with water.
Avoid using skin products that can cause irritation, such as harsh soaps, shampoos, or skin cleansers, hair coloring or permanent chemicals, hair removers or waxes, or skin products with alcohol, spices, astringents, or lime. Do not use other medicated skin products unless your doctor has told you to.
Avoid exposure to sunlight or artificial UV rays (sunlamps or tanning beds). Hydroquinone (White UP) topical can make your skin more sensitive to sunlight and sunburn may result. Use a sunscreen (minimum SPF 15) and wear protective clothing if you must be out in the sun.
See also:
What is the most important information I should know about Mometasone (White UP)?
Do not use Mometasone (White UP) to treat an asthma attack that has already begun. It will not work fast enough. Use only a fast acting inhalation medication.
It may take up to 2 weeks before your symptoms improve. Keep using the medication as directed and tell your doctor if your symptoms do not improve after 2 weeks of treatment.
Your dosage needs may change if you have surgery, are ill, are under stress, or have recently had an asthma attack. Do not change your medication dose or schedule without your doctor's advice.
Seek medical attention if you think any of your asthma medications are not working as well as usual. An increased need for medication could be an early sign of a serious asthma attack.
See also:
What is the most important information I should know about Tretinoin (White UP)?
Avoid exposure to sunlight or artificial UV rays (sunlamps or tanning beds). Tretinoin (White UP) topical can make your skin more sensitive to sunlight and sunburn may result. Use a sunscreen (minimum SPF 15) and wear protective clothing if you must be out in the sun.
Avoid getting this medication in your eyes, mouth, and nose, or on your lips. If it does get into any of these areas, wash with water. Do not use Tretinoin (White UP) topical on sunburned, windburned, dry, chapped, irritated, or broken skin. Also avoid using this medication in wounds or on areas of eczema. Wait until these conditions have healed before using Tretinoin (White UP) topical.
Use this medication for as many days as it has been prescribed for you even if you think it is not working. It may take weeks or months of use before you notice improvement in your skin. If you are using Tretinoin (White UP) topical to treat acne, your condition may get slightly worse for a short time when you first start using the medication. Call your doctor if skin irritation becomes severe or if your acne does not improve within 8 to 12 weeks.
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What are the possible side effects of Hydroquinone (White UP)?
Mild burning, stinging, redness, and dryness may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.
If your doctor has prescribed this medication, remember that he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.
Stop using Hydroquinone (White UP) and tell your doctor right away if any of these unlikely but serious side effects occur: blistering, skin cracking, blue-black darkening of the skin.
A very serious allergic reaction to this drug is rare. However, seek immediate medical attention if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.
This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.
In the US -
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch.
In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.
See also:
What are the possible side effects of Mometasone (White UP)?
Applies to Mometasone (White UP): inhalation aerosol powder, inhalation powder
In addition to its needed effects, some unwanted effects may be caused by Mometasone (White UP) (the active ingredient contained in Mometasone (White UP)). In the event that any of these side effects do occur, they may require medical attention.
Major Side EffectsYou should check with your doctor immediately if any of these side effects occur when taking Mometasone (White UP):
More common:
Some of the side effects that can occur with Mometasone (White UP) may not need medical attention. As your body adjusts to the medicine during treatment these side effects may go away. Your health care professional may also be able to tell you about ways to reduce or prevent some of these side effects. If any of the following side effects continue, are bothersome or if you have any questions about them, check with your health care professional:
More common:
See also:
What are the possible side effects of Tretinoin (White UP)?
Clinical Trials Experience
Because clinical trials are conducted under widely varying conditions, adverse reaction rates observed in the clinical trials of a drug cannot be directly compared to rates in the clinical trials of another drug and may not reflect the rates observed in practice.
Clinical Trials in Subjects with Acne
In separate clinical trials for each concentration, acne subjects treated with Tretinoin (White UP) gel, USP (microsphere) 0.1% or 0.04%, over the twelve week period showed that cutaneous irritation scores for erythema, peeling, dryness, burning/stinging, or itching peaked during the initial two weeks of therapy, decreasing thereafter.
Approximately half of the subjects treated with Tretinoin (White UP) gel, USP (microsphere) 0.04% had cutaneous irritation at Week 2. Of those subjects who did experience cutaneous side effects, most had signs or symptoms that were mild in severity (severity was ranked on a 4-point ordinal scale: 0=none, 1=mild, 2=moderate, and 3=severe). Less than 10% of patients experienced moderate cutaneous irritation and there was no severe irritation at Week 2.
In trials of Tretinoin (White UP) gel, USP (microsphere) 0.04%, throughout the treatment period the majority of subjects experienced some degree of irritation (mild, moderate, or severe) with 1% (2/225) of subjects having scores indicative of a severe irritation; 1.3% (3/225) of subjects treated with Tretinoin (White UP) gel, USP (microsphere) 0.04%, discontinued treatment due to irritation, which included dryness in one patient and peeling and urticaria in another.
In trials of Tretinoin (White UP) gel, USP (microsphere) 0.1%, no more than 3% of subjects had cutaneous irritation scores indicative of severe irritation; 6% (14/224) of subjects treated with Tretinoin (White UP) gel, USP (microsphere) 0.1% discontinued treatment due to irritation. Of these 14 subjects, four had severe irritation after 3 to 5 days of treatment, with blistering in one subject.
In a double-blind trial with 156 acne subjects comparing 12 weeks of treatment with Tretinoin (White UP) gel, USP (microsphere) 0.04% or 0.1% (78 subjects each group), the most frequently-reported adverse events affected the skin and subcutaneous tissue (15.4% in the 0.04% group, and 20.5% in the 0.1% group). The most prevalent of the dermatologic adverse events in the 0.04% group was skin irritation (6.4%); and in the 0.1% group skin burning (7.7%), erythema (5.1%), skin irritation (3.8%), and dermatitis (3.8%). Most adverse events were of mild intensity (63.4%), and 34.4% were moderate. One subject in each group had adverse events characterized as severe, neither were dermatologic findings and neither was characterized as related to drug by the investigator.
Trials in Subjects Without Acne
In a half-face comparison trial conducted for up to 14 days in women with sensitive skin, but without acne, Tretinoin (White UP) gel, USP (microsphere) 0.1% was statistically less irritating than Tretinoin (White UP) cream, 0.1%. In addition, a cumulative 21 day irritation evaluation in subjects with normal skin showed that Tretinoin (White UP) gel, USP (microsphere) 0.1%, had a lower irritation profile than Tretinoin (White UP) cream, 0.1%. The clinical significance of these irritation trials for patients with acne is not established. Comparable effectiveness of Tretinoin (White UP) gel, USP (microsphere) 0.1% and Tretinoin (White UP) cream, 0.1%, has not been established. The lower irritancy of Tretinoin (White UP) gel, USP (microsphere) 0.1% in subjects without acne may be attributable to the properties of its vehicle. The contribution of decreased irritancy by the methyl methacrylate/glycol dimethacrylate crosspolymer porous microspheres has not been established. No irritation trials have been performed to compare Tretinoin (White UP) gel, USP (microsphere) 0.04%, with either Tretinoin (White UP) gel, USP (microsphere) 0.1%, or Tretinoin (White UP) cream, 0.1%.
Postmarketing Experience
The following adverse reactions have been identified during post-approval use of Tretinoin (White UP) gel, USP (microsphere). Because these reactions are reported voluntarily from a population of uncertain size, it is not always possible to reliably estimate their frequency or establish a casual relationship to drug exposure.
Temporary hyper- or hypopigmentation has been reported with repeated application of Tretinoin (White UP).
ALPHAQUIN HP 4% CREAMNUQUIN HP 4% CREAM, NUQUIN HP 4% GEL, MELPAQUE HP 4% CREAM, MELQUIN HP 4% CREAM and Hydroquinone (White UP) (Hydroquinone (White UP) 3% topical solution) are indicated for the gradual bleaching of hyperpigmented skin conditions such as chloasma, melasma, freckles, senile lentigines and other undesired areas of melanin hyperpigmentation.
An indication is a term used for the list of condition or symptom or illness for which the medicine is prescribed or used by the patient. For example, acetaminophen or paracetamol is used for fever by the patient, or the doctor prescribes it for a headache or body pains. Now fever, headache and body pains are the indications of paracetamol. A patient should be aware of the indications of medications used for common conditions because they can be taken over the counter in the pharmacy meaning without prescription by the Physician.Mometasone (White UP) is a cortisone-like steroid available in cream, ointment, and lotion form. It is used to treat certain itchy rashes and other inflammatory skin conditions.
An indication is a term used for the list of condition or symptom or illness for which the medicine is prescribed or used by the patient. For example, acetaminophen or paracetamol is used for fever by the patient, or the doctor prescribes it for a headache or body pains. Now fever, headache and body pains are the indications of paracetamol. A patient should be aware of the indications of medications used for common conditions because they can be taken over the counter in the pharmacy meaning without prescription by the Physician.(To understand fully the indication for this product, please read the entire INDICATIONS AND USAGE section of the labeling.)
Complex A™ Tretinoin (White UP) Cream, USP (Emollient) 0.05% is indicated as an adjunctive agent for use in the mitigation (palliation) of fine wrinkles, mottled hyperpigmentation, and tactile roughness of facial skin in patients who do not achieve such palliation using comprehensive skin care and sun avoidance programs. COMPLEX A™ Tretinoin (White UP) CREAM, USP (EMOLLIENT) DOES NOT ELIMINATE WRINKLES, REPAIR SUN-DAMAGED SKIN, REVERSE PHOTOAGING, or RESTORE A MORE YOUTHFUL or YOUNGER DERMAL HISTOLOGIC PATTERN. Many patients achieve desired palliative effects on fine wrinkling, mottled hyperpigmentation, and tactile roughness of facial skin with the use of comprehensive skin care and sun avoidance programs including sunscreens, protective clothing, and emollient creams NOT containing Tretinoin (White UP).
Complex A™ Tretinoin (White UP) Cream, USP (Emollient) 0.05% should be used under medical supervision as an adjunct to a comprehensive skin care and sun avoidance program that includes the use of effective sun-screens (minimum SPF of 15) and protective clothing when desired results on fine wrinkles, mottled hyperpigmentation, and roughness of facial skin have not been achieved with a comprehensive skin care and sun avoidance program alone.
The effectiveness of Complex A™ Tretinoin (White UP) Cream, USP (Emollient) 0.05% in the mitigation of fine wrinkles, mottled hyperpigmentation, and tactile roughness of facial skin has not been established in people greater than 50 years of age OR in people with moderately to heavily pigmented skin. In addition, patients with visible actinic keratoses and patients with a history of skin cancer were excluded from clinical trials of Complex A™ Tretinoin (White UP) Cream, USP (Emollient) 0.05%. Thus the effectiveness and safety of Complex A™ Tretinoin (White UP) Cream, USP (Emollient) 0.05% in these populations are not known at this time.
Hydroquinone (White UP) decreases the formation of melanin in the skin. Melanin is the pigment in skin that gives it a brown color.
Hydroquinone (White UP) topical (for the skin) is used to lighten areas of darkened skin such as freckles, age spots, melasma (sun damage), or chloasma (darkened skin caused by hormonal changes).
Hydroquinone (White UP) topical may also be used for purposes not listed in this medication guide.
Mometasone (White UP) is used to help prevent the symptoms of asthma and improve breathing in patients 4 years of age and older. When used regularly every day, inhaled Mometasone (White UP) decreases the number and severity of asthma attacks. However, it will not relieve an asthma attack that has already started.
Mometasone (White UP) HFA is used as a maintenance treatment for the prevention and control of asthma symptoms in patients 12 years of age and older.
Inhaled Mometasone (White UP) belongs to the family of medicines known as corticosteroids (cortisone-like medicines). It works by preventing certain cells in the lungs and breathing passages from releasing substances that cause asthma symptoms.
Mometasone (White UP) is available only with your doctor's prescription.
Tretinoin (White UP) is used to treat acne. It works partly by keeping skin pores clear.
One of the Tretinoin (White UP) creams is used to treat fine wrinkles, dark spots, or rough skin on the face caused by damaging rays of the sun. It works by lightening the skin, replacing older skin with newer skin, and by slowing down the way the body removes skin cells that may have been harmed by the sun. Tretinoin (White UP) works best when used within a skin care program that includes protecting the treated skin from the sun. However, it does not completely or permanently erase these skin problems or greatly improve more obvious changes in the skin, such as deep wrinkles caused by sun or the natural aging process.
Tretinoin (White UP) may also be used to treat other skin diseases as determined by your doctor.
Tretinoin (White UP) is available only with your doctor's prescription.
Once a medicine has been approved for marketing for a certain use, experience may show that it is also useful for other medical problems. Although this use is not included in product labeling, Tretinoin (White UP) is used in certain patients with the following medical conditions:
Hydroquinone (White UP) is a topical lightening product found in OTC products, and is used to correct skin discoloration associated with disorders of hyperpigmentation including melasma, post-inflammatory hyperpigmention, sunspots, and freckles. It can be used alone, but is more frequently found in combination with other agents such as alpha-hydroxy acids, corticosteroids, retinoids, or sunscreen. Hydroquinone (White UP) has come under scrutiny due to several complications associated with its use, including dermal irritation, exogenous onchronosis, and carginogenicity. As a result of these concerns, Hydroquinone (White UP) has been banned in the EU and UK.
Mometasone (White UP) is a medium-potency synthetic corticosteroid with anti-inflammatory, antipruritic, and vasoconstrictive properties. Studies in asthmatic patients have demonstrated that Mometasone (White UP) provides a favorable ratio of topical to systemic activity due to its primary local effect along with the extensive hepatic metabolism and the lack of active metabolites. Though effective for the treatment of asthma, glucocorticoids do not affect asthma symptoms immediately. Maximum improvement in symptoms following inhaled administration of Mometasone (White UP) furoate may not be achieved for 1 to 2 weeks or longer after starting treatment. The anti-inflammatory actions of corticosteroids are thought to involve phospholipase A2 inhibitory proteins, lipocortins, which control the biosynthesis of potent mediators of inflammation such as prostaglandins and leukotrienes.
Tretinoin (White UP), also known as all-trans-retinoic acid (ATRA), is a naturally occurring derivative of vitamin A (retinol). Retinoids such as Tretinoin (White UP) are important regulators of cell reproduction, proliferation, and differentiation and are used to treat acne and photodamaged skin and to manage keratinization disorders such as ichthyosis and keratosis follicularis. Tretinoin (White UP) also represents the class of anticancer drugs called differentiating agents and is used in the treatment of acute promyelocytic leukemia (APL).
Use Hydroquinone (White UP) cream as directed by your doctor. Check the label on the medicine for exact dosing instructions.
Ask your health care provider any questions you may have about how to use Hydroquinone (White UP) cream.
Use Mometasone (White UP) spray as directed by your doctor. Check the label on the medicine for exact dosing instructions.
Ask your health care provider any questions you may have about how to use Mometasone (White UP) spray.
Use Tretinoin (White UP) emollient cream as directed by your doctor. Check the label on the medicine for exact dosing instructions.
Ask your health care provider any questions you may have about how to use Tretinoin (White UP) emollient cream.
There are specific as well as general uses of a drug or medicine. A medicine can be used to prevent a disease, treat a disease over a period or cure a disease. It can also be used to treat the particular symptom of the disease. The drug use depends on the form the patient takes it. It may be more useful in injection form or sometimes in tablet form. The drug can be used for a single troubling symptom or a life-threatening condition. While some medications can be stopped after few days, some drugs need to be continued for prolonged period to get the benefit from it.Hydroquinone (White UP) is used to lighten the dark patches of skin (also called hyperpigmentation, melasma, "liver spots," "age spots," freckles) caused by pregnancy, birth control pills, hormone medicine, or injury to the skin.
This medicine works by blocking the process in the skin that leads to discoloration.
How to use Hydroquinone (White UP) topicalFollow all directions on the product package, or use as directed by your doctor. Before using, apply a small amount of this medicine to an area of unbroken skin, and check the area within 24 hours for any serious side effects. If the test area is itching, red, puffy, or blistering, do not use this product and contact your doctor. If there is just mild redness, then treatment with this product may begin.
Apply this medication to the affected areas of skin, usually twice daily or as directed by your doctor. This medication is for use on the skin only. If it is used incorrectly, unwanted skin lightening may occur. Avoid getting this product in your eyes or on the inside of your nose or mouth. If you do get this medication in those areas, flush with plenty of water.
This medication may make the treated areas of skin more sensitive to the sun. Avoid prolonged sun exposure, tanning booths, and sunlamps. Use a sunscreen and wear protective clothing on the treated areas of skin when outdoors.
Use this medication regularly to get the most benefit from it. To help you remember, use it at the same times each day.
Inform your doctor if your condition persists or worsens after 2 months.
There are specific as well as general uses of a drug or medicine. A medicine can be used to prevent a disease, treat a disease over a period or cure a disease. It can also be used to treat the particular symptom of the disease. The drug use depends on the form the patient takes it. It may be more useful in injection form or sometimes in tablet form. The drug can be used for a single troubling symptom or a life-threatening condition. While some medications can be stopped after few days, some drugs need to be continued for prolonged period to get the benefit from it.Mometasone (White UP) is used to treat used to treat the inflammation and itching caused by a number of skin conditions such as allergic reactions, eczema, and psoriasis. It is also used to relieve symptoms of hay fever, allergies of nose and nasal polyps (fleshy swelling inside the nose).
There are specific as well as general uses of a drug or medicine. A medicine can be used to prevent a disease, treat a disease over a period or cure a disease. It can also be used to treat the particular symptom of the disease. The drug use depends on the form the patient takes it. It may be more useful in injection form or sometimes in tablet form. The drug can be used for a single troubling symptom or a life-threatening condition. While some medications can be stopped after few days, some drugs need to be continued for prolonged period to get the benefit from it.Use: Labeled IndicationsAcute promyelocytic leukemia (remission induction): Induction of remission in patients with acute promyelocytic leukemia, French American British (FAB) classification M3 (including the M3 variant) characterized by t(15;17) translocation and/or PML/RARα gene presence
Off Label UsesAcute promyelocytic leukemia (consolidation therapy)
Data from studies of combination chemotherapy in adults with acute promyelocytic leukemia (APL) support the use of Tretinoin (White UP) as part of the consolidation phase of treatment.
Generic name: Hydroquinone (White UP) 40mg in 1g
Dosage form: gel
See also:
Medically reviewed on August 11, 2018.
Hydroquinone (White UP) should be applied daily at night to affected areas and rubbed in well, or as directed by a physician. If no lightening effect is seen after 2 months of treatment, use of this product should be discontinued.
During the day, avoid sunlight exposure to treated areas by using an effective broad spectrum sunscreen (SPF 15 or higher) or by wearing sun-protective clothing.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Medical Disclaimer
More about Glytone Skin Lightening (Hydroquinone (White UP) topical)
Other brands: Hydroquinone (White UP) and Sunscreen, Hydroquinone (White UP), Eldoquin, Esoterica,... +22 more
Professional resourcesAdminister Mometasone (White UP) by the orally inhaled route only. Instruct patients to inhale rapidly and deeply. Advise patients to rinse the mouth after inhalation. Individual patients will experience a variable time to onset and degree of symptom relief. Maximum benefit may not be achieved for 1 to 2 weeks or longer after initiation of treatment. After asthma stability has been achieved, it is desirable to titrate to the lowest effective dosage to reduce the possibility of side effects. For patients ≥12 years of age who do not respond adequately to the starting dose after 2 weeks of therapy, higher doses may provide additional asthma control. The safety and efficacy of Mometasone (White UP) when administered in excess of recommended doses have not been established.
Recommended Dosages in Patients 4 Years of Age and Older
The recommended starting doses and highest recommended daily dose for Mometasone (White UP) treatment based on prior asthma therapy are provided in Table 1.
Patients require detailed instruction to obtain maximal benefits and to understand all the precautions necessary to use this product with greatest safety. The physician should review the Patient Package Insert.
Complex A™ Tretinoin (White UP) Cream, USP (Emollient) should be applied to the face once a day before retiring, using only enough to cover the entire affected area lightly. Patients should gently wash their faces with a mild soap, pat the skin dry, and wait 20 to 30 minutes before applying Complex A™ Tretinoin (White UP) Cream, USP (Emollient). The patient should apply a pea-sized amount of cream to cover the entire face lightly. Special caution should be taken when applying the cream to avoid the eyes, ears, nostrils, and mouth.
Application of Complex A™ Tretinoin (White UP) Cream, USP (Emollient) may cause a transitory feeling of warmth or slight stinging.
Mitigation (palliation) of facial fine wrinkling, mottled hyperpigmentation, and tactile roughness may occur gradually over the course of therapy. Up to six months of therapy may be required before the effects are seen. Most of the improvement noted with Complex A™ Tretinoin (White UP) Cream, USP (Emollient) 0.05% is seen during the first 24 weeks of therapy. Thereafter, therapy primarily maintains the improvement realized during the first 24 weeks.
With discontinuation of Complex A™ Tretinoin (White UP) Cream, USP (Emollient) 0.05% therapy, a majority of patients will lose most mitigating effects of Complex A™ Tretinoin (White UP) Cream, USP (Emollient) 0.05% on fine wrinkles, mottled hyperpigmentation, and tactile roughness of facial skin; however, the safety and effectiveness of using Complex A™ Tretinoin (White UP) Cream, USP (Emollient) 0.05% daily for greater than 48 weeks have not been established.
Application of larger amounts of medication than recommended may not lead to more rapid results or better results, and marked redness, peeling, or discomfort may occur.
Patients treated with Complex A™ Tretinoin (White UP) Cream, USP (Emollient) 0.05% may use cosmetics, but the areas to be treated should be cleansed thoroughly before the medication is applied.
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What other drugs will affect Hydroquinone (White UP)?
Your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them. Do not start, stop, or change the dosage of any medicine before checking with your doctor or pharmacist first.
Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use.
Keep a list of all your medications with you, and share the list with your doctor and pharmacist.
See also:
What other drugs will affect Mometasone (White UP)?
In clinical trials, concurrent administration of ASMANEX HFA and other drugs, such as short-acting beta2-agonist and intranasal corticosteroids have not resulted in an increased frequency of adverse drug reactions. No formal drug interaction studies have been performed with ASMANEX HFA.
Inhibitors Of Cytochrome P450 3A4The main route of metabolism of corticosteroids, including Mometasone (White UP) furoate, is via CYP3A4. After oral administration of ketoconazole, a strong inhibitor of CYP3A4, the mean plasma concentration of orally inhaled Mometasone (White UP) furoate increased. Concomitant administration of CYP3A4 inhibitors may inhibit the metabolism of, and increase the systemic exposure to, Mometasone (White UP) furoate. Caution should be exercised when considering the coadministration of ASMANEX HFA with long-term ketoconazole and other known strong CYP3A4 inhibitors (e.g., ritonavir, atazanavir, clarithromycin, indinavir, itraconazole, nefazodone, nelfinavir, saquinavir, telithromycin).
See also:
What other drugs will affect Tretinoin (White UP)?
Limited clinical data on potential drug interactions are available.
Drugs Metabolized By the Hepatic P450 SystemAs Tretinoin (White UP) (Tretinoin (White UP)) is metabolized by the hepatic P450 system, there is a potential for alteration of pharmacokinetics parameters in patients administered concomitant medications that are also inducers or inhibitors of this system. Medications that generally induce hepatic P450 enzymes include rifampicin, glucocorticoids, phenobarbital and pentobarbital. Medications that generally inhibit hepatic P450 enzymes include ketoconazole, cimetidine, erythromycin, verapamil, diltiazem and cyclosporine. To date there are no data to suggest that co-use with these medications increases or decreases either efficacy or toxicity of Tretinoin (White UP) (Tretinoin (White UP)).
Agents Known to Cause Pseudotumor Cerebri/Intracranial Hypertension (Such as Tetracyclines)Tretinoin (White UP) (Tretinoin (White UP)) may cause pseudotumor cerebri/intracranial hypertension. Concomitant administration of Tretinoin (White UP) (Tretinoin (White UP)) and agents known to cause pseudotumor cerebri/intracranial hypertension as well might increase the risk of this condition.
Vitamin AAs with other retinoids, Tretinoin (White UP) (Tretinoin (White UP)) must not be administered in combination with vitamin A because symptoms of hypervitaminosis A could be aggravated.
Anti-fibrinolytic Agents (Such as Tranexamic Acid, Aminocaproic Acid, or Aprotinin)Cases of fatal thrombotic complications have been reported rarely in patients concomitantly treated with Tretinoin (White UP) (Tretinoin (White UP)) and anti-fibrinolytic agents. Therefore, caution should be exercised when administering Tretinoin (White UP) (Tretinoin (White UP)) concomitantly with these agents.
Effect of FoodNo data on the effect of food on the absorption of Tretinoin (White UP) (Tretinoin (White UP)) are available. The absorption of retinoids as a class has been shown to be enhanced when taken together with food.
