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Tums

Tums has a relatively narrow international footprint, registered in seven countries that span several continents rather than clustering in one region — Argentina, Canada, Israel, the Philippines, Portugal, the United Kingdom, and the United States. The brand is long-established in some of these markets, particularly North America and the United Kingdom, where it is a familiar fixture on pharmacy and supermarket shelves.

The active ingredient is calcium carbonate, classified within the antacid category and also recognised as a mineral used in compensating calcium deficiency. In its Tums formulation the ingredient is positioned for the symptomatic relief of dyspepsia, heartburn, and flatulence — common complaints linked to excess stomach acid. The structured indication list further down this page sets out the registered uses in the markets where Tums is sold.

Travellers familiar with Tums from North America or the UK will not always find the same brand abroad, even though calcium carbonate itself is one of the most universally available active ingredients in the world. In countries where Tums is not registered, the same molecule is typically sold under a different antacid brand name, and other mineral-based antacids in the same broader class are also widely available.

A pharmacist in the destination country is the right person to point out a locally registered calcium carbonate product, or a comparable antacid if calcium carbonate is not the preferred option there. While antacids are often sold without prescription, recurring or persistent symptoms of indigestion or heartburn are worth raising with a healthcare provider rather than managing indefinitely on over-the-counter products alone.

Overdose

Hypercalcaemia -Remove source of calcium. Rehydration may be necessary (if necessary with intravenous 0.9% sodium chloride) and a loop diuretic may be given to increase urinary calcium excretion.

Shelf life

3 years.

Incompatibilities

None known.

List of excipients

All Flavour Tablets

Microcrystalline Cellulose

Maize Starch

Dextrose Monohydrate

Sodium Saccharin

Magnesium Stearate

Blackcurrant Flavour Tablets

Patent Blue V Lake E131

Ponceau 4R Lake E124

Blackcurrant Flavour 9/696044

Cherry Flavour Tablets

Ponceau 4R Lake E124

Cherry Flavour 630277F

Lemon Flavour Tablets

Quinoline Yellow Lake E104

Lemon Flavour 610364E

Orange Flavour Tablets

Sunset Yellow Lake E110

Orange Flavour 655280 SD

Undesirable effects

Calcium Carbonate can cause constipation and flatulence. Hypercalcaemia can occur as can alkalosis following the regular use of Calcium Carbonate. The milk-alkali syndrome has occasionally occurred in patients taking large doses. 'Acid Rebound' has been reported on cessation of Calcium Carbonate.

Reporting of suspected adverse reactions

Reporting suspected adverse reactions after authorisation of the medicinal product is important. It allows continued monitoring of the benefit/risk balance of the medicinal product. Healthcare professionals are asked to report any suspected adverse reactions via the Yellow Card Scheme at: www.mhra.gov.uk/yellowcard.

Preclinical safety data

Not applicable.

Pharmacodynamic properties

Antacid.

Mechanism of Action/Effect

Calcium Carbonate reacts chemically to neutralise or buffer existing quantities of stomach acid but has no direct effect on its output. This action results in increased pH value of stomach contents, thus providing relief of hyperacidity symptoms. It also reduces acid concentration within the lumen of the oesophagus, thus causing an increase in intra-oesophageal pH and a decrease in pepsin activity, which aids the control of gastro-oesophageal reflux.

ATC code: A02AC01.

Pharmacokinetic properties

Not applicable.

Date of revision of the text

03/01/2018

Marketing authorisation holder

Wrafton Laboratories Limited Wrafton Braunton North Devon EX33 2DL

Special precautions for storage

Do not store above 25°C.

Nature and contents of container

250 micron clear white UPVC/20 micron hard temper, heat seal coated aluminium foil. 24, 48, 72, 96 tablets/carton.

Polypropylene bottle with polyethylene tamper evident caps 72, 75, 95, 100 tablets/bottle.

Roll wrap of 20 tablets in 9 micron soft aluminium foil/6 gsm wax/20 gsm paper. 40, 60, 80, 100, 120 packs will be 2, 3, 4, 5, 6 rolls in a carton.

Roll wrap of 12 tablets in 9 micron soft aluminium foil/6 gsm wax/20 gsm paper. 24, 36, 48, 60, 72, 96 packs will be 2, 3, 4, 5, 6, 8 rolls in a carton.

Marketing authorisation number(s)

PL 12063/0013.

Special warnings and precautions for use

If symptoms persist consult your doctor. Keep all medicines out of the sight and reach of children.

The leaflet shall say:

Each tablet contains 523 mg of glucose (dextrose) per tablet. This should be taken into account in patients with diabetes mellitus.

If you have been told by your doctor that you have an intolerance to some sugars, contact your doctor before taking this medicinal product.

Effects on ability to drive and use machines

None known.

Special precautions for disposal and other handling

None.

ADMINISTRATION DETAILS

Date of first authorisation/renewal of the authorisation

28 July1993

Frequently asked questions

What conditions does Tums treat?

Tums is used for the symptomatic relief of dyspepsia, heartburn, and flatulence. It belongs to the antacid category and acts in the upper gastrointestinal tract to neutralise excess stomach acid. Because its active ingredient is also a mineral, the same molecule appears in other contexts as a calcium supplement. The structured indication block further down this page details the registered uses recognised in each market where Tums is sold.

Which active substance is in Tums?

Tums contains calcium carbonate, classified as an antacid and also as a mineral used in compensating calcium deficiency. Calcium carbonate is one of the most widely circulated active ingredients in the world and appears under a wide range of brand names internationally, sometimes positioned as an antacid and sometimes as a mineral supplement, depending on the formulation and the regulatory market.

In how many countries is Tums available?

Tums is registered in seven countries, with a geographically scattered footprint rather than a tight regional cluster. The markets include the United States, the United Kingdom, Canada, Argentina, the Philippines, Israel, and Portugal. If your country is not on this list, calcium carbonate antacid products are typically available locally under different brand names — a pharmacist can help identify a comparable product where you are.

Are there other medications with the same active ingredient as Tums?

Calcium carbonate is sold under many brand names worldwide, both as an antacid and as a mineral supplement, and is among the most broadly available over-the-counter ingredients in regulated markets. Other medications in the antacid class — based on different mineral salts — also exist internationally. To identify a local equivalent, search the active ingredient on Pill2Trip or ask a pharmacist about antacid options available in your country.

Do I need a doctor's advice about Tums?

While calcium carbonate antacids are often available without prescription, persistent or recurring symptoms of dyspepsia or heartburn warrant a conversation with a healthcare provider rather than ongoing self-management. Regulatory status, pack sizes, and concurrent-medication considerations also vary between countries, which matters for travellers and people relocating. A pharmacist or doctor familiar with the patient's circumstances is the right person to guide use.