Tums

Overdose

Hypercalcaemia -Remove source of calcium. Rehydration may be necessary (if necessary with intravenous 0.9% sodium chloride) and a loop diuretic may be given to increase urinary calcium excretion.

Shelf life

3 years.

Incompatibilities

None known.

List of excipients

All Flavour Tablets

Microcrystalline Cellulose

Maize Starch

Dextrose Monohydrate

Sodium Saccharin

Magnesium Stearate

Blackcurrant Flavour Tablets

Patent Blue V Lake E131

Ponceau 4R Lake E124

Blackcurrant Flavour 9/696044

Cherry Flavour Tablets

Ponceau 4R Lake E124

Cherry Flavour 630277F

Lemon Flavour Tablets

Quinoline Yellow Lake E104

Lemon Flavour 610364E

Orange Flavour Tablets

Sunset Yellow Lake E110

Orange Flavour 655280 SD

Undesirable effects

Calcium Carbonate can cause constipation and flatulence. Hypercalcaemia can occur as can alkalosis following the regular use of Calcium Carbonate. The milk-alkali syndrome has occasionally occurred in patients taking large doses. 'Acid Rebound' has been reported on cessation of Calcium Carbonate.

Reporting of suspected adverse reactions

Reporting suspected adverse reactions after authorisation of the medicinal product is important. It allows continued monitoring of the benefit/risk balance of the medicinal product. Healthcare professionals are asked to report any suspected adverse reactions via the Yellow Card Scheme at: www.mhra.gov.uk/yellowcard.

Preclinical safety data

Not applicable.

Pharmacodynamic properties

Antacid.

Mechanism of Action/Effect

Calcium Carbonate reacts chemically to neutralise or buffer existing quantities of stomach acid but has no direct effect on its output. This action results in increased pH value of stomach contents, thus providing relief of hyperacidity symptoms. It also reduces acid concentration within the lumen of the oesophagus, thus causing an increase in intra-oesophageal pH and a decrease in pepsin activity, which aids the control of gastro-oesophageal reflux.

ATC code: A02AC01.

Pharmacokinetic properties

Not applicable.

Date of revision of the text

03/01/2018

Marketing authorisation holder

Wrafton Laboratories Limited Wrafton Braunton North Devon EX33 2DL

Special precautions for storage

Do not store above 25°C.

Nature and contents of container

250 micron clear white UPVC/20 micron hard temper, heat seal coated aluminium foil. 24, 48, 72, 96 tablets/carton.

Polypropylene bottle with polyethylene tamper evident caps 72, 75, 95, 100 tablets/bottle.

Roll wrap of 20 tablets in 9 micron soft aluminium foil/6 gsm wax/20 gsm paper. 40, 60, 80, 100, 120 packs will be 2, 3, 4, 5, 6 rolls in a carton.

Roll wrap of 12 tablets in 9 micron soft aluminium foil/6 gsm wax/20 gsm paper. 24, 36, 48, 60, 72, 96 packs will be 2, 3, 4, 5, 6, 8 rolls in a carton.

Marketing authorisation number(s)

PL 12063/0013.

Special warnings and precautions for use

If symptoms persist consult your doctor. Keep all medicines out of the sight and reach of children.

The leaflet shall say:

Each tablet contains 523 mg of glucose (dextrose) per tablet. This should be taken into account in patients with diabetes mellitus.

If you have been told by your doctor that you have an intolerance to some sugars, contact your doctor before taking this medicinal product.

Effects on ability to drive and use machines

None known.

Special precautions for disposal and other handling

None.

ADMINISTRATION DETAILS

Date of first authorisation/renewal of the authorisation

28 July1993