See also:
What is the most important information I should know about Folic acid (Quantus)?
Because it may mask the hematologic abnormalities while neurological damage progresses, Folic acid (Quantus) should not be used in the therapy of patients with vitamin B12 deficiency of any cause, unless there is associated folate deficiency. The Folic acid (Quantus) content of one tablet a day however, is unlikely to mask pernicious anemia should this condition be present. Also, pregnancy during pernicious anemia is very rare.
Most Significant
Lactating Mother, Pregnancy, Prostatic Carcinoma, Selenium Toxicity, Wilson’s Disease
Possibly Significant
Vitamin K Deficiency Induced Hypoprothrombinemia
See also:
What is the most important information I should know about Selenium (Quantus)?
Selenium (Quantus) Injection should not be given undiluted by direct injection into a peripheral vein because of the potential for infusion phlebitis.
See also:
What is the most important information I should know about Zinc (Quantus)?
Hypersensitivity to any of the ingredients of Zinc (Quantus).
See also:
What are the possible side effects of Coenzyme Q10 (Quantus)?
Nausea, Night sweats, Pneumonitis, Abnormal breathing, Altered sperm motility, Chest pain, Constipation, Cough, Diarrhoea, Difficulty in paying attention, Fainting, Fatigue, Fungal infection of skin, Headache, Hearing loss, Heartburn, Indigestion, Influenza like symptoms, Insomnia, Rash, Itching, Loss of appetite, Low energy, Muscle pain, Respiratory tract infection, Running nose, Sinus infection, Sinus inflammation, Sore throat, Stomach pain, Stomach upset, Trembling, Vomiting
See also:
What are the possible side effects of Folic acid (Quantus)?
Allergic sensitization has been reported following both oral and parenteral administration of Folic acid (Quantus).
Folic acid (Quantus) is relatively nontoxic in man. Rare instances of allergic responses to Folic acid (Quantus) preparations have been reported and have included erythema, skin rash, itching, general malaise, and respiratory difficulty due to bronchospasm. One patient experienced symptoms suggesting anaphylaxis following injection of the drug. Gastrointestinal side effects, including anorexia, nausea, abdominal distention, flatulence, and a bitter or bad taste, have been reported in patients receiving 15 mg Folic acid (Quantus) daily for 1 month. Other side effects reported in patients receiving 15 mg daily include altered sleep patterns, difficulty in concentrating, irritability, overactivity, excitement, mental depression, confusion, and impaired judgment. Decreased vitamin B12 serum levels may occur in patients receiving prolonged Folic acid (Quantus) therapy.
In an uncontrolled study, orally administered Folic acid (Quantus) was reported to increase the incidence of seizures in some epileptic patients receiving phenobarbital, primidone, or diphenylhydantoin. Another investigator reported decreased diphenylhydantoin serum levels in folate-deficient patients receiving diphenylhydantoin who were treated with 5 mg or 15 mg of Folic acid (Quantus) daily.
CALL YOUR DOCTOR FOR MEDICAL ADVICE ABOUT SIDE EFFECTS. YOU MAY REPORT SIDE EFFECTS TO THE FDA AT 1-800-FDA-1088 OR LEADING PHARMA, LLC AT 844-740-7500.
Abdominal bloating, Abdominal pain, Abnormality of blood, Allergy, Decreased blood pressure, Diarrhoea, Gout, Airway inflammation, Worsening of asthma
Rare:
Abdominal Pain with Cramps, Back Pain, Blurred Vision, Constipation, Diarrhea, Dizziness, Dysuria, Erectile Dysfunction, Fatigue, Headache Disorder, Hypertension, Libido Changes, Nausea, Urinary Retention
See also:
What are the possible side effects of Selenium (Quantus)?
Applies to Selenium (Quantus) sulfide topical: topical cream, topical foam, topical lotion, topical shampoo, topical suspension
As well as its needed effects, Selenium (Quantus) sulfide topical may cause unwanted side effects that require medical attention.
Severity: ModerateIf any of the following side effects occur while taking Selenium (Quantus) sulfide topical, check with your doctor or nurse as soon as possible:
Less common or rare:
Some Selenium (Quantus) sulfide topical side effects may not need any medical attention. As your body gets used to the medicine these side effects may disappear. Your health care professional may be able to help you prevent or reduce these side effects, but do check with them if any of the following side effects continue, or if you are concerned about them:
More common:
See also:
What are the possible side effects of Zinc (Quantus)?
Applies to Zinc (Quantus) sulfate: capsules, tablets
Check with your doctor if any of these most COMMON side effects persist or become bothersome:
Nausea; vomiting.
Seek medical attention right away if any of these SEVERE side effects occur while taking Zinc (Quantus) sulfate (the active ingredient contained in Zinc (Quantus))
Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); severe vomiting; unusual restlessness; very dry mouth, eyes, or skin.
Supplementing the amount of coenzyme Q-10 in the diet.
Coenzyme Q-10 is a dietary supplement.
An indication is a term used for the list of condition or symptom or illness for which the medicine is prescribed or used by the patient. For example, acetaminophen or paracetamol is used for fever by the patient, or the doctor prescribes it for a headache or body pains. Now fever, headache and body pains are the indications of paracetamol. A patient should be aware of the indications of medications used for common conditions because they can be taken over the counter in the pharmacy meaning without prescription by the Physician.Folic acid (Quantus) is used in the treatment and prevention of the folate deficiency state. It does not correct folate deficiency due to dihydrofolate reductase inhibitors. Folic acid (Quantus) is also used in women of child-bearing potential and pregnant women to protect against neural tube defects in their offspring. It is also used for the treatment of folate-deficient megaloblastic anaemia, chronic haemolytic states such as thalassaemia major or sickle-cell anaemia.
An indication is a term used for the list of condition or symptom or illness for which the medicine is prescribed or used by the patient. For example, acetaminophen or paracetamol is used for fever by the patient, or the doctor prescribes it for a headache or body pains. Now fever, headache and body pains are the indications of paracetamol. A patient should be aware of the indications of medications used for common conditions because they can be taken over the counter in the pharmacy meaning without prescription by the Physician.Used for nutritional supplementation, also for treating dietary shortage or imbalance. (Acromegaly; Gigantism; Hyperammonemia; Hypophysectomy; Panhypopituitarism; Pituitary dwarfism; chromophobe adenoma; pituitary trauma; postsurgical craniopharyngioma; problems of growth and stature; urea cycle disorders;)
An indication is a term used for the list of condition or symptom or illness for which the medicine is prescribed or used by the patient. For example, acetaminophen or paracetamol is used for fever by the patient, or the doctor prescribes it for a headache or body pains. Now fever, headache and body pains are the indications of paracetamol. A patient should be aware of the indications of medications used for common conditions because they can be taken over the counter in the pharmacy meaning without prescription by the Physician.These compounds act mainly as normalizatoare of cellular metabolic process. ale fenomenelor oxidative si de imbatranire. Alterations mentioned processes underlying degenerative processes of cell aging and oxidative phenomena
An indication is a term used for the list of condition or symptom or illness for which the medicine is prescribed or used by the patient. For example, acetaminophen or paracetamol is used for fever by the patient, or the doctor prescribes it for a headache or body pains. Now fever, headache and body pains are the indications of paracetamol. A patient should be aware of the indications of medications used for common conditions because they can be taken over the counter in the pharmacy meaning without prescription by the Physician.Oral
Selenium (Quantus) deficiency
Adult: 100-500 mcg of Selenium (Quantus) daily.
IntramuscularSelenium (Quantus) deficiency
Adult: 100-500 mcg of Selenium (Quantus) daily.
IntravenousSelenium (Quantus) deficiency
Adult: 100-500 mcg of Selenium (Quantus) daily.
An indication is a term used for the list of condition or symptom or illness for which the medicine is prescribed or used by the patient. For example, acetaminophen or paracetamol is used for fever by the patient, or the doctor prescribes it for a headache or body pains. Now fever, headache and body pains are the indications of paracetamol. A patient should be aware of the indications of medications used for common conditions because they can be taken over the counter in the pharmacy meaning without prescription by the Physician.Patients with deficiency of B-complex vitamins, vitamin C and Zinc (Quantus) or where supplementation of these vitamins and Zinc (Quantus) can be beneficial. Such patients and conditions include: Patients who are on prolonged antibiotic therapy; those who are suffering from infection, injuries, burns, fever, illness; patients with diarrhoea and GI disorders; patients who have undergone surgical operations; patients on diet restrictions eg, in diabetes, anorexia and alcoholism and in elderly persons; pregnant and lactating women due to increased nutritional needs.
Coenzyme Q10 (Quantus) is a vitamin-like substance that is made naturally in the body. This medicine is also known as Coenzima, Ubidcarenone, Ubidécarénone, and Ubiquinol.
Coenzyme Q10 (Quantus) is likely effective in alternative medicine as an aid in treating coenzyme Q-10 deficiency, or reducing the symptoms of mitochondrial disorders (conditions that affect energy-production in the cells of the body).
Coenzyme Q10 (Quantus) is also possibly effective in preventing migraine headaches, lowering blood pressure, preventing a second heart attack, or slowing the progression of early Parkinson's disease. This medicine is also possibly effective in improving symptoms in people with congestive heart failure, nerve problems caused by diabetes, Huntington's disease, muscular dystrophy, or macular degeneration (age-related vision loss).
Coenzyme Q10 (Quantus) has also been used to treat Alzheimer's disease, high cholesterol, or amyotrophic lateral sclerosis (Lou Gehrig's disease). However, research has shown that this medicine may not be effective in treating these conditions.
Research also has shown that Coenzyme Q10 (Quantus) is not likely to be effective in increasing athletic performance.
Other uses not proven with research have included treating asthma, COPD, cancer, diabetes, certain heart problems, fibromyalgia, hepatitis C, kidney problems, high blood pressure during pregnancy, muscle problems caused by taking "statin" cholesterol medicine, and other conditions.
Coenzyme Q10 (Quantus) is often sold as an herbal supplement. There are no regulated manufacturing standards in place for many herbal compounds and some marketed supplements have been found to be contaminated with toxic metals or other drugs. Herbal/health supplements should be purchased from a reliable source to minimize the risk of contamination.
Vitamins are compounds that you must have for growth and health. They are needed in small amounts only and are usually available in the foods that you eat. Folic acid (Quantus) (vitamin B 9) is necessary for strong blood.
Lack of Folic acid (Quantus) may lead to anemia (weak blood). Your health care professional may treat this by prescribing Folic acid (Quantus) for you.
Some conditions may increase your need for Folic acid (Quantus). These include:
In addition, infants smaller than normal, breast-fed infants, or those receiving unfortified formulas (such as evaporated milk or goat's milk) may need additional Folic acid (Quantus).
Increased need for Folic acid (Quantus) should be determined by your health care professional.
Some studies have found that Folic acid (Quantus) taken by women before they become pregnant and during early pregnancy may reduce the chances of certain birth defects (neural tube defects).
Claims that Folic acid (Quantus) and other B vitamins are effective for preventing mental problems have not been proven. Many of these treatments involve large and expensive amounts of vitamins.
Injectable Folic acid (Quantus) is given by or under the direction of your health care professional. Another form of Folic acid (Quantus) is available without a prescription.
Selenium (Quantus) is mineral that is found in soil and occurs naturally in certain foods (such as whole grains, Brazil nuts, sunflower seeds, and seafood). Selenium (Quantus) is not produced in the body, but it is needed for proper thyroid and immune system function.
Selenium (Quantus) is used to treat or prevent Selenium (Quantus) deficiency.
Selenium (Quantus) has been used in alternative medicine as an aid to treat Hashimoto's thyroiditis (an autoimmune disorder of the thyroid), and to treat high cholesterol.
Not all uses for Selenium (Quantus) have been approved by the FDA. Selenium (Quantus) should not be used in place of medication prescribed for you by your doctor.
Selenium (Quantus) may also be used for purposes not listed in this product guide.
Zinc (Quantus) is a naturally occurring mineral. Zinc (Quantus) is important for growth and for the development and health of body tissues.
Zinc (Quantus) sulfate is used to treat and to prevent Zinc (Quantus) deficiency.
Zinc (Quantus) sulfate may also be used for purposes not listed in this medication guide.
A member of the vitamin B family that stimulates the hematopoietic system. It is present in the liver and kidney and is found in mushrooms, spinach, yeast, green leaves, and grasses (poaceae). Folic acid (Quantus) is used in the treatment and prevention of folate deficiencies and megaloblastic anemia. [PubChem]
An essential amino acid that is physiologically active in the L-form. [PubChem]
Lycopene (Quantus), an antioxidant, is indicated for the treatment and prevention of cancer, cataract, asthma, HPV infection, atherosclerosis, CVD and prostate cancer. Lycopene (Quantus) is a good anti-inflammatory agent and anti-oxidant.
Zinc (Quantus) Capsule: Each capsule contains Zinc (Quantus) sulphate monohydrate 54.93 mg, thiamine nitrate 10 mg, riboflavin 10 mg, pyridoxine hydrochloride 3 mg, vitamin B12 (coated) equivalent to cyanocobalamin 15 mcg, ascorbic acid 150 mg, Zinc (Quantus) 1 mg, nicotinamide 50 mg and calcium pantothenate 12.5 mg.
Zinc (Quantus) Syrup: Each 5 mL contains Zinc (Quantus) gluconate 34.9 mg, thiamine mononitrate 2.5 mg, riboflavin 2.5 mg, pyridoxine hydrochloride 1 mg, cyanocobalamin 3 mcg, ascorbic acid 50 mg, d-panthenol 12.5 mg and niacinamide 25 mg in a flavoured liquid glucose sorbitol syrup base.
Use Coenzyme Q10 (Quantus) as directed by your doctor. Check the label on the medicine for exact dosing instructions.
Ask your health care provider any questions you may have about how to use Coenzyme Q10 (Quantus).
Use Folic acid (Quantus) as directed by your doctor. Check the label on the medicine for exact dosing instructions.
Ask your health care provider any questions you may have about how to use Folic acid (Quantus).
Use Selenium (Quantus) lotion as directed by your doctor. Check the label on the medicine for exact dosing instructions.
Ask your health care provider any questions you may have about how to use Selenium (Quantus) lotion.
There are specific as well as general uses of a drug or medicine. A medicine can be used to prevent a disease, treat a disease over a period or cure a disease. It can also be used to treat the particular symptom of the disease. The drug use depends on the form the patient takes it. It may be more useful in injection form or sometimes in tablet form. The drug can be used for a single troubling symptom or a life-threatening condition. While some medications can be stopped after few days, some drugs need to be continued for prolonged period to get the benefit from it.Coenzyme Q10 (Quantus) (CoQ10), also known as ubiquinone is a naturally occuring vitamin like substance found in the body. It is used as a preventive therapy for aging heart problems, and in treating heart failure, gum diseases, type 2 diabetes and high blood pressure. CoQ10 is also being used as supportive therapy for various nerve and muscle-related disorders, as well as few rare inherited disorders. CoQ10 should never be used in place of prescribed medcations for any of the above diseases, as it cannot cure these diseases when taken alone.
There are specific as well as general uses of a drug or medicine. A medicine can be used to prevent a disease, treat a disease over a period or cure a disease. It can also be used to treat the particular symptom of the disease. The drug use depends on the form the patient takes it. It may be more useful in injection form or sometimes in tablet form. The drug can be used for a single troubling symptom or a life-threatening condition. While some medications can be stopped after few days, some drugs need to be continued for prolonged period to get the benefit from it.Folic acid (Quantus) is the man-made form of folate. Folate is a B-vitamin naturally found in some foods. It is needed to form healthy cells, especially red blood cells.
Folic acid (Quantus) supplements may come in different forms (such as L-methylfolate, levomefolate, methyltetrahydrofolate). They are used to treat or prevent low folate levels. Low folate levels can lead to certain types of anemia. Conditions that can cause low folate levels include poor diet, pregnancy, alcoholism, liver disease, certain stomach/intestinal problems, kidney dialysis, among others. Women of childbearing age should receive adequate amounts of Folic acid (Quantus) either through their diet or supplements to prevent infant spinal cord birth defects.
How to use Folic acid (Quantus)Take this product by mouth with or without food as directed by your doctor, usually once daily. If you are taking the over-the-counter product, follow all directions on the product package. If you have any questions, ask your doctor or pharmacist.
Dosage is based on your medical condition and response to treatment. Do not increase your dose or take this product more often than directed.
Take this product regularly to get the most benefit from it. To help you remember, take it at the same time each day. Follow the diet plan recommended by your doctor or dietician. See also Notes section.
If your condition persists or worsens, or if you think you may have a serious medical problem, get medical help right away.
There are specific as well as general uses of a drug or medicine. A medicine can be used to prevent a disease, treat a disease over a period or cure a disease. It can also be used to treat the particular symptom of the disease. The drug use depends on the form the patient takes it. It may be more useful in injection form or sometimes in tablet form. The drug can be used for a single troubling symptom or a life-threatening condition. While some medications can be stopped after few days, some drugs need to be continued for prolonged period to get the benefit from it.L-arginine (Quantus) is used for congestive heart failure, chest pain, high blood pressure, and coronary artery disease. L-arginine (Quantus) is also used for recurrent pain in the legs due to blocked arteries, decreased mental capacity in the elderly, erectile dysfunction, male infertility. L-arginine (Quantus) for preventing the common cold, improving kidney function after a kidney transplant, high blood pressure during pregnancy (pre-eclampsia), improving athletic performance, boosting the immune system, and preventing inflammation of the digestive tract in premature infants.
There are specific as well as general uses of a drug or medicine. A medicine can be used to prevent a disease, treat a disease over a period or cure a disease. It can also be used to treat the particular symptom of the disease. The drug use depends on the form the patient takes it. It may be more useful in injection form or sometimes in tablet form. The drug can be used for a single troubling symptom or a life-threatening condition. While some medications can be stopped after few days, some drugs need to be continued for prolonged period to get the benefit from it.Selenium (Quantus) is used as a dietary supplement mainly in the treatment of Selenium (Quantus) deficiency affecting young women and children with Keshan disease. It is also used for treatment of osteoarthiritis associated with poor Selenium (Quantus) levels in body called Kashin-Beck Disease. Selenium (Quantus) supplements are also used in patients with HIV/ AIDS to maintain the adequate Selenium (Quantus) levels.
25 mg: 1-4 softcaps daily. 100 mg: 1 softcap daily.
Usual Adult Dose for Megaloblastic Anemia1 mg orally, intramuscularly, subcutaneously or IV once a day. May continue until clinical symptoms of folate deficiency and the hematological profile have normalized.
Usual Adult Dose for Folic acid (Quantus) Deficiency
400 to 800 mcg orally, intramuscularly, subcutaneously or IV once a day.
Women of childbearing age, pregnant, and lactating women: 800 mcg orally, intramuscularly, subcutaneously or IV once a day.
Usual Pediatric Dose for Folic acid (Quantus) Deficiency
Infant:
0.1 mg orally, intramuscularly, subcutaneously or IV once a day.
Child:
Less than 4 years: up to 0.3 mg orally, intramuscularly, subcutaneously or IV once a day.
4 years or older: 0.4 mg orally, intramuscularly, subcutaneously or IV once a day.
Usual Pediatric Dose for Vitamin/Mineral Supplementation
Recommended daily allowance (RDA):
Premature neonates: 50 mcg/day (15 mcg/kg/day).
Full-term neonates and infants 1 to 6 months: 25 to 35 mcg/day.
Children:
1 to 3 years: 150 mcg/day.
4 to 8 years: 200 mcg/day.
9 to 13 years: 300 mcg/day.
14 years and older: 400 mcg/day.
Renal Dose Adjustments
Data not available
Liver Dose Adjustments
Data not available
Dose Adjustments
Rarely, a dosage of 2 mg/day may be required, particularly in patients with malabsorption, alcoholism, chronic hemolysis, chronic exfoliative skin disease or who are on concomitant anticonvulsant therapy.
Dialysis
Folic acid (Quantus) is removed by both hemodialysis and peritoneal dialysis. The amount removed varies with type equipment used.
Because folate may accumulate in patients with end-stage renal disease, side effects may be more likely in this patient who is undergoing dialysis. Once this patient's body stores of folate are replete, three times a week dosing may be just as beneficial as once daily dosing but should portend a lower risk of side effects.
Other Comments
The recommended daily allowance of Folic acid (Quantus) for adult males and females ranges from 150 to 200 and 150 to 180 mcg/day, respectively.
There is a potential danger in administering Folic acid (Quantus) to patients with undiagnosed anemia, since Folic acid (Quantus) may obscure the diagnosis of pernicious anemia by alleviating the hematologic manifestations of the disease while allowing the neurologic complications to progress.
Severe megaloblastic anemia may require therapy for 4 to 5 weeks. Once stabilized, if dietary intake is inadequate, maintenance therapy can be started.
Dosage depends on the severity of the catabolic state & amino acid requirement. Daily dose: 10-20ml/kg body wt equiv to 1-2g amino acids/kg body wt. Maximum daily dosage not >2g amino acids/kg body wt.
Selenium (Quantus) Injection provides 40 mcg Selenium (Quantus)/mL. For metabolically stable adults receiving TPN, the suggested additive dosage level is 20 to 40 mcg Selenium (Quantus)/day. For pediatric patients, the suggested additive dosage level is 3 mcg/kg/day.
In adults, Selenium (Quantus) deficiency states resulting from long-term TPN support, Selenium (Quantus) as selenomethionine or selenious acid, administered intravenously at 100 mcg/day for a period of 24 and 31 days, respectively, has been reported to reverse deficiency symptoms without toxicity.
Aseptic addition of Selenium (Quantus) Injection to the TPN solution under laminar flow hood is recommended. Selenium (Quantus) is physically compatible with the electrolytes and other trace elements usually present in amino-acid/dextrose solution used for TPN. Frequent monitoring of plasma Selenium (Quantus) levels is suggested as a guideline for subsequent administration. The normal whole blood range for Selenium (Quantus) is approximately 10 to 37 mcg/100 mL.
Parenteral drug products should be inspected visually for particulate matter and discoloration, whenever solution and container permit.
Zinc (Quantus) 1 mg/mL (Zinc (Quantus) Chloride Injection, USP) contains 1 mg Zinc (Quantus)/mL and is administered intravenously only after dilution. The additive should be diluted prior to administration in a volume of fluid not less than 100 mL. For the metabolically stable adult receiving TPN, the suggested intravenous dosage is 2.5 to 4 mg Zinc (Quantus)/day (2.5 to 4 mL/day). An additional 2 mg Zinc (Quantus)/day (2 mL/day) is suggested for acute catabolic states. For the stable adult with fluid loss from the small bowel, an additional 12.2 mg Zinc (Quantus)/liter of small bowel fluid lost (12.2 mL/liter of small bowel fluid lost), or an additional 17.1 mg Zinc (Quantus)/kg of stool or ileostomy output (17.1 mL/kg of stool or ileostomy output) is recommended. Frequent monitoring of Zinc (Quantus) blood levels is suggested for patients receiving more than the usual maintenance dosage level of Zinc (Quantus).
For full term infants and children up to 5 years of age, 100 mcg Zinc (Quantus)/kg/day
(0.1 mL/kg/day) is recommended. For premature infants (birth weight less than 1500 g) up to 3 kg in body weight, 300 mcg Zinc (Quantus)/kg/day (0.3 mL/kg/day) is suggested.
Parenteral drug products should be inspected visually for particulate matter and discoloration prior to administration, whenever solution and container permit. See PRECAUTIONS.
How suppliedZinc (Quantus) 1 mg/mL (Zinc (Quantus) Chloride Injection, USP) is supplied in 10 mL Plastic Vials (List No. 4090).
Store at 20 to 25°C (68 to 77°F).
HOSPIRA, INC., LAKE FOREST, IL 60045 USA. Revised: October, 2004
Tell your doctor if you are using any of these:
* a beta blocker blood pressure medication such as atenolol (Tenormin), carvedilol (Coreg), labetalol (Normodyne, Trandate), metoprolol (Lopressor, Toprol), propranolol (Inderal, InnoPran), sotalol (Betapace), and others
* a blood thinner such as warfarin (Coumadin)
* cholesterol lowering agents such as atorvastatin (Lipitor), pravastatin (Pravachol), simvastatin (Zocor), and others
* doxorubicin (Adriamycin); or
* diabetes medication.
See also:
What other drugs will affect Folic acid (Quantus)?
Medications that interfere with your bodys ability to use folate may also increase the need for this vitamin. Medications can interfere with folate utilization, including: anticonvulsant medications (such as phenytoin, and primidone) metformin (sometimes prescribed to control blood sugar in type 2 diabetes) sulfasalazine (used to control inflammation associated with Crohns disease and ulcerative colitis) triamterene (a diuretic) Methotrexate There has been concern about the interaction between vitamin B12 and Folic acid (Quantus). Folic acid (Quantus) supplements can correct the anemia associated with vitamin B12 deficiency. Unfortunately, Folic acid (Quantus) will not correct changes in the nervous system that result from vitamin B12 deficiency. Permanent nerve damage could theoretically occur if vitamin B12 deficiency is not treated. Therefore, intake of supplemental Folic acid (Quantus) should not exceed 1000 micrograms (g, sometimes mcg) per day to prevent Folic acid (Quantus) from masking symptoms of vitamin B12 deficiency. It is important for older adults to be aware of the relationship between Folic acid (Quantus) and vitamin B12 because they are at greater risk of having a vitamin B12 deficiency. If you are 50 years of age or older, ask your physician to check your B12 status before you take a supplement that contains Folic acid (Quantus).
ALPHA TOCOPHERYL/SELECTED ANTICOAGULANTS - Increased effect of the latter drug
DI-TRIVALENT CATIONS/TETRACYCLINES - Decreased effect of the latter drug
Moderate Interaction:
Assess the risk to the patient and take action as needed.
POLYVALENT CATIONS/ELTROMBOPAG - Decreased effect of the latter drug
SELECTED MINERALS/ORAL IRON SUPPLEMENTS - Decreased effect of the latter drug
DI-; TRIVALENT CATIONS/CHLOROQUINE; HYDROXYCHLOROQUINE - Decreased effect of the former drug
ORAL MULTIVALENT CATIONS/ORAL BISPHOSPHONATES - Decreased effect of the latter drug
FAT SOLUBLE VITAMINS/ORLISTAT - Decreased effect of the former drug
ORAL ZINC PRODUCTS/SELECTED ORAL QUINOLONES - Decreased effect of the latter drug
See also:
What other drugs will affect Selenium (Quantus)?
Baloxavir Marboxil: Polyvalent Cation Containing Products may decrease the serum concentration of Baloxavir Marboxil. Avoid combination
Bictegravir: Polyvalent Cation Containing Products may decrease the serum concentration of Bictegravir. Management: Administer bictegravir under fasting conditions at least 2 hours before or 6 hours after polyvalent cation containing products. Coadministration of bictegravir with or 2 hours after most polyvalent cation products is not recommended. Consider therapy modification
Bisphosphonate Derivatives: Polyvalent Cation Containing Products may decrease the serum concentration of Bisphosphonate Derivatives. Management: Avoid administration of oral medications containing polyvalent cations within: 2 hours before or after tiludronate/clodronate/etidronate; 60 minutes after oral ibandronate; or 30 minutes after alendronate/risedronate. Exceptions: Pamidronate; Zoledronic Acid. Consider therapy modification
Deferiprone: Polyvalent Cation Containing Products may decrease the serum concentration of Deferiprone. Management: Separate administration of deferiprone and oral medications or supplements that contain polyvalent cations by at least 4 hours. Consider therapy modification
Dolutegravir: Selenium (Quantus) may decrease the serum concentration of Dolutegravir. Management: Administer dolutegravir at least 2 hours before or 6 hours after oral Selenium (Quantus). Administer the dolutegravir/rilpivirine combination product at least 4 hours before or 6 hours after oral Selenium (Quantus). Consider therapy modification
Eltrombopag: Polyvalent Cation Containing Products may decrease the serum concentration of Eltrombopag. Management: Administer eltrombopag at least 2 hours before or 4 hours after oral administration of any polyvalent cation containing product. Consider therapy modification
Elvitegravir: Polyvalent Cation Containing Products may decrease the serum concentration of Elvitegravir. Management: Administer elvitegravir 2 hours before or 6 hours after the administration of polyvalent cation containing products. Consider therapy modification
PenicillAMINE: Polyvalent Cation Containing Products may decrease the serum concentration of PenicillAMINE. Management: Separate the administration of penicillamine and oral polyvalent cation containing products by at least 1 hour. Consider therapy modification
Raltegravir: Polyvalent Cation Containing Products may decrease the serum concentration of Raltegravir. Management: Administer raltegravir 2 hours before or 6 hours after administration of the polyvalent cations. Dose separation may not adequately minimize the significance of this interaction. Consider therapy modification
Trientine: Polyvalent Cation Containing Products may decrease the serum concentration of Trientine. Management: Avoid concomitant administration of trientine and oral products that contain polyvalent cations. If oral iron supplements are required, separate the administration by 2 hours. If other oral polyvalent cations are needed, separate administration by 1 hour. Consider therapy modification
See also:
What other drugs will affect Zinc (Quantus)?
Pyridoxine reduces the effects of levodopa (but this does not occur if a dopa decarboxylase is also given); decreases serum concentrations of phenobarbitone. Concurrent administration of drugs eg, isoniazid, penicillamine and oral contraceptives increase the requirement for pyridoxine.
Absorption of cyanocobalamin from the GIT may be reduced by neomycin, aminosalicylic acid, histamine H2-receptor antagonists and colchicine. Serum concentrations may be decreased by concurrent administration of oral contraceptives. Many of these interactions are unlikely to be of clinical significance but should be taken into account when performing assays for blood concentrations.
Parenteral chloramphenicol may attenuate the effect of vitamin B12 in anaemia.
Folate deficiency states may be produced by a number of drugs including antiepileptics, oral contraceptives, antituberculous drugs, alcohol and Zinc (Quantus) antagonists eg, aminopterin, methotrexate, pyrimethamine, trimethoprim and sulphonamides; Zinc (Quantus) may decrease serum-phenytoin concentrations.
There may be an increased risk of myopathy or rhabdomyolysis when nicotinic acid is used concurrently with statins. Nicotinamide may increase the requirements for insulin or oral hypoglycaemics.
Ascorbic acid may increase the absorption of iron-deficiency states.
Ascorbic acid is often given in addition to desferrioxamine to patients with iron overload (thalassemia) to achieve better iron excretion. However, early on in treatment when there is excess tissue iron, there is some evidence that ascorbic acid may worsen the iron toxicity, particularly to the heart. Thus, ascorbic acid should not be given for the first month after starting desferrioxamine treatment.
The absorption of Zinc (Quantus) may be reduced by iron supplements, penicillamine, phosphorus-containing preparations and tetracyclines. Zinc (Quantus) supplements reduce the absorption of copper, ciprofloxacin, iron, norfloxacin, penicillamine and tetracyclines.
