Treatment: hemosorption, symptomatic therapy.
30 months.
acute intermittent porphyria,
lactation period,
Concomitant administration of drugs that inhibit hematopoiesis (sulfonamides, cytostatics), which affect the metabolism in the liver, with radiation therapy increases the risk of side effects.
Borax
Boric acid
Purified water
Substance-powder
skin rash, angioedema.
There are no preclinical data of relevance to the prescriber which are additional to that already included in other sections of the SPC.
Diseases caused by sensitive microorganisms:
brain abscess,
typhoid fever,
salmonellosis (mainly generalized forms),
Ku fever,
pneumonia,
biliary tract infections,
typhoid fever,
Ku fever,
yersiniosis,
A broad-spectrum bacteriostatic antibiotic that disrupts the process of protein synthesis in the microbial cell at the stage of transfer of t-RNA amino acids to ribosomes. It is effective against bacterial strains resistant to penicillins, tetracyclines, and sulfonamides.
, , Salmonella spp., Streptococcus spp., (incl. ), Haemophilus influenzae
Mycobacterium tuberculosisAcinetobacter spp.Enterobacter spp.Serratia marcescens, protozoa and fungi.
after intravenous administration-1-1. 5 h. V
max in the cerebrospinal fluid, it is determined in 4-5 hours after a single oral administration and can reach 21-50% of C in the absence of inflammation of the meninges
The main amount (90%) is metabolized in the liver. In the intestine, under the influence of intestinal bacteria, it is hydrolyzed to form inactive metabolites.
in children from 1 month to 16 years-3-6. 5 hours, in newborns from 1 to 2 days-24 hours or more (especially varies in children with low birth weight), 10-16 days — 10 hours.
It is poorly excreted during hemodialysis.
May 2016
Minims Chloramphenicol 0.5%
Bausch & Lomb UK Limited
Bausch & Lomb House
106 London Road
Kingston-Upon-Thames
Surrey, UK
KT2 6TN
At a temperature not exceeding 25 °C. After opening, store the drug in the refrigerator at t 2-8 °C, use for 15 days.
powder for the preparation of eye drops 120 mg — 2 years.
| Powder for making eye drops | |
| colistimethate sodium | |
in aluminum tubes of 5 g, in a pack of cardboard 1 tube.
PL 03468/0069
In severe infections topical use of chloramphenicol should be supplemented with appropriate systemic treatment.
Aplastic anaemia has, rarely, followed topical use of chloramphenicol eye drops and, whilst this hazard is an uncommon one, it should be borne in mind when the benefits of the use of chloramphenicol are assessed.
Prolonged use should be avoided as it may increase the likelihood of sensitisation and the emergence of resistant organisms.
Contact lenses should be removed during the period of treatment.
Systemic absorption may be reduced by compressing the lacrimal sac at the medial canthus for a minute during and following the instillation of the drops. (This blocks the passage of the drops via the naso lacrimal duct to the wide absorptive area of the nasal and pharyngeal mucosa. It is especially advisable in children.)
May cause transient blurring of vision on installation. Warn patients not to drive or operate hazardous machinery unless vision is clear.
V/vin/m
Cracked nipples — after each feeding, the nipples are washed with a 0.25% solution of ammonia, then a sterile cloth covered with a layer of liniment is applied to the crack.
On the skin, spray from a distance of 20-30 cm for 1-3 seconds 2-3 times a week, with severe lesions, the drug can be used daily.
Each Minims unit should be discarded after a single use.
If the product is to be stored unrefrigerated at temperatures not exceeding 25°C, prior to supply of the product by the pharmacy the adhesive label provided in the carton should be completed and affixed over the bar code, by a pharmacist. An expiry date one month from the supply date, plus the pharmacist's initials should be written in the spaces provided on this label.
| Date of Grant: Date of Renewal: | 31.7.91 23.4.97 |
