See also:
What is the most important information I should know about Klb6?
Contraindications for Klb6
Klb6 is contraindicated in those hypersensitive to any component of a Klb6-containing product.
See also:
What are the possible side effects of Klb6?
Applies to pyridoxine: capsule, injectable, solution, tablet, tablet enteric coated, tablet extended release
As well as its needed effects, pyridoxine (the active ingredient contained in Klb6) may cause unwanted side effects that require medical attention.
Severity: ModerateIf any of the following side effects occur while taking pyridoxine, check with your doctor or nurse as soon as possible:
With large doses
* Sideroblastic anaemia
* Treatment and prophylaxis of Klb6 deficiency states
Pyridoxine is Klb6. Vitamins occur naturally in foods such as meat, poultry, nuts, whole grains, bananas, and avocados. Klb6 is important for many processes in the body.
Pyridoxine is used to treat or prevent Klb6 deficiency. It is also used to treat a certain type of anemia (lack of red blood cells). Pyridoxine injection is also used to treat some types of seizure in babies.
Pyridoxine taken by mouth (oral) is available without a prescription. Injectable pyridoxine must be given by a healthcare professional.
Pyridoxine may also be used for purposes not listed in this medication guide.
The 4-methanol form of vitamin B 6 which is converted to pyridoxal phosphate which is a coenzyme for synthesis of amino acids, neurotransmitters (serotonin, norepinephrine), sphingolipids, aminolevulinic acid. Although pyridoxine and Vitamin B 6 are still frequently used as synonyms, especially by medical researchers, this practice is erroneous and sometimes misleading (EE Snell; Ann NY Acad Sci, vol 585 pg 1, 1990).
Follow all directions on your prescription label. Do not use this medicine in larger or smaller amounts or for longer than recommended.
Pyridoxine tablets are taken by mouth. Injectable pyridoxine is injected into a muscle or into a vein through an IV. You may be shown how to use injections at home. Do not self-inject this medicine if you do not understand how to give the injection and properly dispose of used needles, IV tubing, and other items used to inject the medicine.
The recommended dietary allowance of pyridoxine increases with age. Follow your healthcare provider's instructions. You may also consult the Office of Dietary Supplements of the National Institutes of Health, or the U.S. Department of Agriculture (USDA) Nutrient Database (formerly "Recommended Daily Allowances") listings for more information.
Pyridoxine is only part of a complete program of treatment that may also include a special diet. It is very important to follow the diet plan created for you by your doctor or nutrition counselor. You should become very familiar with the list of foods you should eat or avoid to help control your condition.
Store at room temperature away from moisture and heat.
There are specific as well as general uses of a drug or medicine. A medicine can be used to prevent a disease, treat a disease over a period or cure a disease. It can also be used to treat the particular symptom of the disease. The drug use depends on the form the patient takes it. It may be more useful in injection form or sometimes in tablet form. The drug can be used for a single troubling symptom or a life-threatening condition. While some medications can be stopped after few days, some drugs need to be continued for prolonged period to get the benefit from it.It is used for the treatment and prevention of Klb6 deficiency. It is important for the breakdown of protein, fats, and carbohydrates from foods.
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What other drugs will affect Klb6?
Interactions for Klb6
Amiodarone: Concomitant use of Klb6 and amiodarone may enhance amiodarone-induced photosensitivity reactions. Doses of Klb6 greater than 5-10 milligrams/day should be avoided by those taking amiodarone Carbamazepine: Chronic use of carbamazepine may result in a significant decrease in plasma pyridoxal 5-phosphate levels Cycloserine: Cycloserine may react with pyridoxal 5-phosphate to form a metabolically inactive oxime, which may result in a functional Klb6 deficiency Ethionamide: The use of ethionamide may increase Klb6 requirements Fosphenytoin: High doses of Klb6 may lower plasma levels of phenytoin. Fosphenytoin is a prodrug of phenytoin Hydralazine: The use of hydralazine may increase Klb6 requirements Isoniazid: (isonicotinic acid, INH). Isoniazid reacts with pyridoxal 5-phosphate to form a metabolically inactive hydrazone, which may result in functional Klb6 deficiency Levodopa: Concomitant use of levodopa and Klb6 in doses of 5 milligrams or more daily may reverse the therapeutic effects of levodopa. Klb6 does not reverse the therapeutic effects of levodopa if levodopa is taken concurrently with the levodopa decarboxylase inhibitor carbidopa. Levodopa is typically administered as a combination product with carbidopa
Oral contraceptives: The use of oral contraceptives may increase Klb6 requirements. This was more the case with the older oral contraceptive agents with high-dose estrogen/progestin. It appears to be less the case with the newer low-dose estrogen/progestin products Penicillamine: Penicillamine may react with pyridoxal 5-phosphate to form a metabolically inactive thiazolidine, which may result in a functional Klb6 deficiency Phenelzine: Phenelzine may react with pyridoxal 5-phosphate to yield a metabolically inactive hydrazone compound Phenobarbital: High doses of Klb6 may lower plasma levels of phenobarbital Phenytoin: High doses of Klb6 may lower plasma levels of phenytoin Theophylline: Theophylline may react with pyridoxal 5-phosphate leading to low plasma levels of the coenzyme. This may increase the risk of theophylline-induced seizures Valproic acid: Chronic use of valproic acid may result in a significant decrease in plasma pyridoxal 5-phosphate levels.
