At temperatures below 25 °C.
Keep out of reach of children.
Shelf life of the drug Disol2 года.Do not use after the expiration date indicated on the package.
Instructions for medical useDisol
Instructions for medical use-RU no. LP-002713
Last modified date: 22.03.2017
Dosage formSolution for infusion
Composition1 liter of the drug contains:
Active ingredients:
Sodium chloride 6.0 g
Sodium Acetate Trihydrate 2.0 g
Auxiliary substance
Water for injection up to 1 l
Ionic composition per 1 l:
Sodium ion 117.4 mmol
The chloride ion of 102.7 mmol
The acetate-ion 14.7 mmol
Theoretical osmolarity 235 mOsm/l
Description of the dosage formClear, colorless liquid.
Pharmacological GroupRehydrating agent.
PharmacodynamicsCombined salt solution for rehydration and detoxification. Restores the water-electrolyte balance and acid-base state in the body during dehydration. Prevents the development of metabolic acidosis, increases diuresis. It has a plasma-substituting, detoxifying, rehydrating effect.
PharmacokineticsIt is excreted by the kidneys.
IndicationsDehydration, hyperkalemia, intoxication on the background of dehydration (cholera, acute dysentery, food poisoning).
ContraindicationsKidney and heart failure.
With caution
With caution, the drug should be used in hypokalemia.
Use during pregnancy and lactationThe use of the drug during pregnancy is possible only if the intended benefit to the mother exceeds the potential risk to the fetus. You should refrain from breastfeeding during the use of the drug due to the lack of appropriate clinical data.
Method of administration and dosageIntravenous (jet and drip), under the control of laboratory parameters (electrolytes Na, K, SG, acid-base state of the blood). The ratio of the injected fluid and diuresis is determined every 6 hours. Within 1 hour, the jet is injected, then the jet injection is replaced with a drip, for 24-48 hours, at a rate of 40-120 caps/min. Before administration, the solution is heated to 36-38 °C. The solution is administered in the amounts necessary to restore the volume of fluid lost with feces, vomit, urine, and sweat.
In severe forms of diseases (hypovolemic infectious-toxic shock, decompensated metabolic acidosis, anuria), they begin with a jet injection of the drug, followed by a transition to a drip.
With milder forms of diseases (intoxication and dehydration of the body, metabolic acidosis, oliguria), you can limit yourself to drip administration of the drug. After the elimination of hyperkalemia, further water-salt therapy is carried out with solutions of Trisol, Acesol or Chlosol.
Side effectsEdema, tachycardia. In some cases, you may experience the chills.
OverdoseSymptoms: hypokalemia, hypernatremia.
Treatment: correction of electrolyte disorders, control of the level of electrolytes in the blood.
InteractionWhen used together with other drugs, it is necessary to visually monitor the pharmaceutical incompatibility.
Special instructionsTherapy is carried out under the control of hematocrit and the concentration of blood electrolytes.
In general, when dehydration is indicated, the use of solutions for oral rehydration is indicated, and only if such a reception is impossible (for one reason or another), the drug Disol is administered.
Influence on the ability to drive vehicles and mechanisms
The effect of the drug on psychophysiological reactions and the ability to drive vehicles and mechanisms has not been reported.
Release formSolution for infusions.
100, 200, 250, 400, 500 or 1000 ml in polypropylene bottles, capped with welded polypropylene caps.
One bottle together with the instructions for use in a pack of cardboard.
For hospitals
From 1 to 40 bottles of 100, 200, 250, 400, 500 or 1000 ml together with the instructions for use in an amount equal to the number of bottles in a corrugated cardboard box.
Storage conditionsStore at a temperature not exceeding 25 °C.
Keep out of reach of children.
Expiration date2 years.
Do not use after the expiration date!
Conditions of supply of pharmaciesThey are released on prescription.
Дисоль - инструкция по медицинскому применению - РУ № Р N003712/01 от 2012-07-111 liter of solution for injection contains sodium acetate 2 g and sodium chloride 6 g, in glass bottles of 200 or 400 ml.
In/in the drip, it must be heated up to 36-38 °C.
B05BB01 Electrolytes
