Hypersensitivity.
Chills, hyperthermia (with rapid injection into a vein).
Viral hepatitis, asphyxia (including newborns), pneumonia, asthmatic conditions, coronary heart disease, senile retinal degeneration, intoxication.
In a dry place, protected from light, at a temperature of 4-20 °C.
Keep out of reach of children.
Shelf life of the drug Cytochrome C2 года.Do not use after the expiration date indicated on the package.
Instructions for medical useCytochrome C
Instructions for medical use-RU no. LP-000631
Last modified date: 22.12.2016
Dosage formEye drops
Composition1 ml of the drug contains:
Active ingredient:
Cytochrome C1 -2.5 mg
Excipients:
sodium chloride, water for injection.
1 Obtained from the hearts of cattle, horses, and pigs.
Description of the dosage formTransparent reddish-brown liquid
Pharmacological GroupMetabolic agent
Pharmacological (immuno-biological) propertiesA metabolic agent, it has an antihypoxic, trophic effect, stimulates the regeneration processes. It is a catalyst for cellular respiration.
PharmacodynamicsThe mechanism of action of the drug is associated with the presence of iron in the prosthetic group, which can pass from the oxidized state to the reduced state. As a result, endogenous redox reactions and metabolic processes in tissues are accelerated, and oxygen utilization is improved.
PharmacokineticsWhen applied topically, Cytochrome C is not absorbed into the systemic bloodstream, but is completely metabolized in the body. The breakdown of cytochrome C follows the same metabolic pathways as the breakdown of amino acids, and heme, broken down to bilirubin, is excreted in the bile.
IndicationsAs part of complex therapy for corneal dystrophy (primary and secondary), corneal opacification, keratitis (at the stage of epithelialization).
ContraindicationsChildren under 18 years of age. Hypersensitivity to the components of the drug. Pregnancy and the breastfeeding period.
Method of administration and dosageLocally. 1-2 drops in the conjunctival sac 3-4 times a day.
The duration of use of the drug as part of complex therapy is determined by the attending physician, depending on the effectiveness of therapy.
Side effectsAllergic reactions, conjunctival hyperemia, short-term burning sensation in the eye.
OverdoseNo data available.
InteractionInteraction studies have not been conducted.
Special instructionsWhen using other ophthalmic medications at the same time, the interval between their administration should be at least 10-15 minutes.
Influence on the ability to drive vehicles and mechanisms
Patients who have a short-term burning sensation of the eyes after instillation of the drug should not drive vehicles and mechanisms immediately after applying eye drops.
Release formEye drops 0.25%.
2 ml each in glass bottles with a capacity of 5 ml, capped with rubber stoppers and rolled with aluminum caps.
1 bottle with a cap-dropper and instructions for medical use of the drug is placed in a pack of cardboard box.
Storage conditionsIn a place protected from light at a temperature of 4 to 20°C.
The opened bottle should be stored in the refrigerator for no more than 3 days in a closed form.
Keep out of reach of children.
Expiration date2 years.
Do not use after the expiration date.
Conditions of supply of pharmaciesWithout a prescription.
Цитохром C - инструкция по медицинскому применению - РУ № ЛП-000631 от 2016-12-221 bottle contains 4 ml of 0.25% solution for injection, in a package of 10 pcs.
IV or IV (drip), iv 4-8 ml 1-2 times a day for 10-14 days, for heart diseases IV drip at a rate of 30-40 drops/min for 6-8 hours (daily dose 12-32 ml) (4-8 ml of the drug is dissolved in 200 ml of isotonic sodium chloride solution or 5% glucose solution), in the postoperative period IV 4 ml 2 times a day, with asphyxia of newborns in the umbilical vein in the first 2 minutes after birth at a dose of 4 ml, with bronchial asthma in/m 2-4 ml 2 times a day for 14-25 days.
C01CX Other Cardiotonic drugs
