Chlosol

Chlosol Medicine

Contraindications

hypersensitivity,

hyperkalemia,

kidney and heart failure,

alkalosis.

Pharmaceutical form

Colorless transparent liquid.

Undesirable effects

Edema, tachycardia, hyperkalemia. Rarely-chills.

Pharmacy sales terms

According to the recipe.

Special instructions

Therapy is carried out under the control of hematocrit and the concentration of blood electrolytes. With the development of hyperkalemia, the solution can be replaced with a solution of Disol until the electrolyte balance is normalized.

Therapeutic indications

Rehydration, intoxication on the background of dehydration (including cholera, acute dysentery, food poisoning).

Pharmacotherapeutic group

  • Registrationuse tool [Regulators of fluid and electrolyte balance and acid-base balance in combinations]

Pharmacodynamic properties

Combined salt solution for rehydration and detoxification. It has a hemodynamic effect, reducing hypovolemia, preventing blood thickening and the development of metabolic acidosis, improves capillary blood circulation, increases diuresis and has a detoxifying effect.

Special precautions for storage

At a temperature not exceeding 25 °C.

Keep out of reach of children.

Shelf life of the drug Chlosol2 года.

Do not use after the expiration date indicated on the package.

Instructions for medical use

Chlosol
Instructions for medical use-RU No. LS-002584

Last modified date: 06.07.2017

Dosage form

Solution for infusions.

Composition

Sodium acetic acid 3-water in terms of anhydrous salt-3.6 g,

Sodium chloride - 4.75 g,

Potassium chloride-1.5 g,

Water for injection up to-1 l.

Description of the dosage form

Colorless transparent liquid.

Pharmacological Group

Rehydrating agent.

Pharmacological action

Combined salt solution for rehydration and detoxification. It has a hemodynamic effect, reducing hypovolemia, preventing blood thickening and the development of metabolic acidosis, improves capillary blood circulation, increases diuresis and has a detoxifying effect.

Indications

Rehydration, intoxication on the background of dehydration (including cholera, acute dysentery, food poisoning).

Contraindications

Hypersensitivity, hyperkalemia, renal and heart failure, alkalosis.

Method of administration and dosage

Intravenous (jet and drip), under the control of laboratory parameters. Within 1 hour, a solution is administered in an amount corresponding to 7-10 % of the patient's body weight, then the jet injection is replaced with a drip, for 24-48 hours at a rate of 40-120 caps/min. Before administration, the solution is heated to 36-38 °C. The solution is administered in the amounts necessary to restore the volume of fluid lost with feces, vomit, urine, and sweat. The balance of the injected and lost fluid is determined every 6 hours.

Side effects

Edema, tachycardia, hyperkalemia. Rarely-chills.

Special instructions

Therapy is carried out under the control of hematocrit and the concentration of blood electrolytes.

With the development of hyperkalemia, the solution can be replaced with a solution of "Disol" until the electrolyte balance is normalized.

Release form

Solution for infusions of 200 or 400 ml in glass bottles for blood, infusion and transfusion drugs with a capacity of 250 or 450 ml, respectively, capped with rubber stoppers and compressed with aluminum caps.

One bottle with instructions for use and a corrugated cardboard gasket is placed in a cardboard pack.

20 bottles with a capacity of 250 ml or 15 bottles with a capacity of 450 ml together with 5-10 copies of the instructions for use in a cardboard box (for hospitals).

Storage conditions

At a temperature not exceeding 25 °C.

Freezing the drug while maintaining the tightness of the bottle, as well as its non-wetting of the inner surface of its wall, is not a contraindication to its use.

Keep out of reach of children.

Expiration date

2 years.

Do not use after the expiration date indicated on the package.

Conditions of supply of pharmacies

According to the recipe.

Хлосоль - инструкция по медицинскому применению - РУ № ЛС-001514 от 2015-09-09
Хлосоль - инструкция по медицинскому применению - РУ № П N015750/01 от 2009-05-14
Хлосоль - инструкция по медицинскому применению - РУ № ЛС-001514 от 2011-07-29
Хлосоль - инструкция по медицинскому применению - РУ № ЛС-002584 от 2006-12-29
Хлосоль - инструкция по медицинскому применению - РУ № Р N004125/01 от 2005-05-27
Хлосоль - инструкция по медицинскому применению - РУ № ЛС-001514 от 2017-06-13
Хлосоль - инструкция по медицинскому применению - РУ № Р N003418/01 от 2004-06-09

Nature and contents of container

Solution for infusion 1 l
active ingredients:  
sodium acetic acid trihydrate (in terms of anhydrous salt) 3.6 g
sodium chloride 4.75 g
potassium chloride 1.5 g
water for injection up to 1 l
Release form

Solution for infusions. 200 or 400 ml each in glass bottles for blood, infusion and transfusion preparations with a capacity of 250 or 450 ml, respectively, capped with rubber stoppers and compressed with aluminum caps.

1 bottle with a corrugated cardboard gasket is placed in a cardboard pack.

20 bottles with a capacity of 250 ml or 15 bottles with a capacity of 450 ml are placed in a cardboard box (for hospitals).

Nosological classification (ICD-10)

  • A00. 9 Cholera, unspecified
  • A05. 9 Bacterial food poisoning, unspecified
  • A09 Diarrhea and gastroenteritis of suspected infectious origin (dysentery, bacterial diarrhea)
  • E86 reducing the volume of fluid [hypovolemia]

Dosage (Posology) and method of administration

V/v (jet and drip), under the control of laboratory parameters. Within 1 hour, a solution is administered in an amount corresponding to 7-10% of the patient's body weight, then the jet injection is replaced with a drip, for 24-48 hours at a rate of 40-120 drops/min. Before administration, the solution is heated to 36-38 °C. The solution is administered in the amounts necessary to restore the volume of fluid lost with feces, vomit, urine, and sweat. The balance of the injected and lost fluid is determined every 6 hours.

ATC - Anatomical and therapeutic chemical classification

B05BB01 Electrolytes