Calmacide

Overdose

Symptoms: long-term use of the drug in high doses in patients with impaired renal function can cause hypermagnesemia, hypercalcemia, alkalosis, which are manifested by nausea, vomiting, muscle weakness.

Treatment: you should cancel the drug and immediately consult a doctor.

Contraindications

Chewable tabletsJelly beans

For all dosage forms

hypersensitivity to the components of the drug,

severe renal failure,

hypercalcemia,

hypophosphatemia,

nephrocalcinosis,

children under 12 years of age.

Additionally for chewable tablets and chewable tablets (cooling taste)

sucrose/isomaltase deficiency, fructose intolerance, glucose-galactose malabsorption.

Age (up to 12 years).

Incompatibilities

Changes in the acidity of gastric juice during the use of antacids can lead to a decrease in the rate and degree of absorption of other drugs when taken simultaneously, so medications should be taken 1-2 hours before or after taking antacids.

Tetracycline antibiotics, fluoroquinolones, cardiac glycosides, levothyroxine, iron preparations, fluorides, phosphates-with the simultaneous use of antacids, reduce the absorption of these drugs.

Thiazide diuretics — when taken simultaneously with antacids, the concentration of calcium in the blood serum should be regularly monitored.

Undesirable effects

For all dosage forms

If the recommended doses are met, the drug is well tolerated, however, in very rare cases, allergic reactions are possible — rash, Quincke's edema, anaphylactic reactions.

Additionally for chewable tablets (orange)

Long-term use of the drug in high doses in patients with impaired renal function can cause hypermagnesemia, hypercalcemia.

Therapeutic indications

Chewable tabletsJelly beans

Symptoms associated with increased acidity of gastric juice and reflux esophagitis (including those caused by errors in diet, medication, alcohol, coffee, and nicotine abuse):

heartburn,

sour belch,

periodic pain in the stomach area,

a feeling of fullness or heaviness in the epigastric region,

dyspepsia,

dyspepsia of pregnant women.

Hyperacidity of gastric juice, hyperacid gastritis, peptic ulcer of the stomach and duodenum, heartburn, dyspepsia after overeating fatty foods.

Pharmacotherapeutic group

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  • Antacid agent [Antacids in combinations]
  • Antacids in combinations

Pharmacodynamic properties

Antacid drug of local action. Calmacide Tablet® it contains antacid substances-calcium carbonate and magnesium carbonate, which provide fast and long-lasting neutralization of excess hydrochloric acid of gastric juice, thereby having a protective effect on the gastric mucosa. The achievement of a positive effect within 3-5 minutes is due to the good solubility of the tablets and the high content of calcium.

Pharmacokinetic properties

As a result of the Calmacide interaction® with gastric juice, soluble salts of calcium and magnesium are formed in the stomach.

The degree of absorption of calcium and magnesium from these compounds depends on the dose of the drug. The maximum absorption is 10% calcium and 15-20% magnesium. A small amount of absorbed calcium and magnesium is excreted through the kidneys. With impaired renal function, the concentration of calcium and magnesium in the plasma may increase. In the intestine, insoluble compounds are formed from soluble salts, which are excreted with feces.

Qualitative and quantitative composition

Calcium Carbonate, Magnesium Carbonate

Dosage (Posology) and method of administration

Chewable tabletsJelly beans

Inside, chew or hold in your mouth until completely absorbed.

Adults and children over 12 years of age (unless otherwise recommended by the doctor) with the appearance of symptoms-1-2 tables. If necessary, you can repeat the drug after 2 hours.

The maximum daily dose is 11 tablets.

Inside, 1-2 tablets each.