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Calgel

Calgel is a fixed-dose combination of lidocaine hydrochloride and cetylpyridinium chloride, paired in a single oral preparation for the management of pain and inflammation in the mouth and throat. Combination products of this kind bring together a local-anaesthetic ingredient and an antiseptic ingredient so that the symptomatic and antimicrobial aspects of an oral-cavity complaint can be addressed within one formulation rather than two separate products.

Lidocaine hydrochloride is a well-established local anaesthetic, while cetylpyridinium chloride sits within the disinfectant category and is widely used in oral-care preparations. In Calgel, the two ingredients support indications that include gingivitis, stomatitis, pharyngitis, tonsillitis, laryngitis, and teething-related pain — a range that spans both adult oral and throat complaints and the discomfort associated with teething in young children.

Calgel is registered in 13 countries, with a footprint concentrated across Central and Eastern Europe, the Balkans, and parts of the Caucasus. Representative markets include Poland, the United Kingdom, Russia, Georgia, and Croatia. Travellers familiar with Calgel from any of these markets may not encounter the same brand in Western Europe, the Americas, or much of Asia, although lidocaine-based and cetylpyridinium-based oral preparations exist internationally under different brand names and formulations.

Combination oral and throat-care products vary noticeably between countries, both in their precise ingredient pairings and in their regulatory status — some are pharmacy medicines, others are over-the-counter, and guidance on use in young children has shifted in several markets. A local pharmacist can identify a comparable product where Calgel is not sold, and any decision about use, especially for a child, is best made in consultation with a healthcare provider.

Shelf life

3 years (unopened)

Incompatibilities

None known

List of excipients

Sorbitol solution (70%) (E420)

Xylitol (E967)

Ethanol 96%

Glycerol

Hydroxyethyl cellulose 5000

Macrogolglycerol hydroxystearate (Cremophor RH 40) (castor oil polyoxyl hydrogenated)

Macrogol lauryl ether 9

Macrogol 300

Saccharin sodium

Levomenthol

Pharmaceutical liquid flavour, (containing chamomile)

Caramel (E150)

Citric acid monohydrate

Sodium citrate dihydrate

Purified water

Preclinical safety data

No additional information.

Date of revision of the text

02/09/2016

Marketing authorisation holder

McNeil Products Limited

Foundation Park

Roxborough Way

Maidenhead

Berkshire

SL6 3UG

United Kingdom

Special precautions for storage

Do not store above 25°C.

Nature and contents of container

10 g collapsible, internally lacquered, aluminium tube, the nozzle of which possesses a membrane.

Marketing authorisation number(s)

PL 15513/0015

Special precautions for disposal and other handling

No special requirements for disposal

Date of first authorisation/renewal of the authorisation

04.06.99

Frequently asked questions

What is Calgel used for?

Calgel is used for the relief of pain and discomfort associated with conditions of the mouth and throat, including gingivitis, stomatitis, pharyngitis, tonsillitis, laryngitis, and teething syndrome in young children. The combination of a local anaesthetic ingredient with a disinfectant ingredient reflects the dual role typical of oral-care preparations in this category. The structured indication section below this introduction lists each registered use in the markets where Calgel is sold.

What is Calgel made of?

Calgel contains two active ingredients: lidocaine hydrochloride, a local anaesthetic, and cetylpyridinium chloride, an antiseptic compound classified within the disinfectant category. Both molecules are widely used in oral and throat-care preparations worldwide under a variety of brand names; Calgel pairs them within a single product designed for application in the mouth and throat.

In how many countries is Calgel available?

Calgel is registered in 13 countries, with a footprint concentrated across Central and Eastern Europe, the Balkans, and parts of the Caucasus, alongside the United Kingdom and Turkey. Examples include Poland, Russia, Croatia, Georgia, the United Kingdom, and Romania. If your country is not represented on this list, a local pharmacist can usually confirm whether a comparable lidocaine- or cetylpyridinium-based oral preparation is available locally.

Are there other medications with the same active ingredients as Calgel?

Lidocaine and cetylpyridinium chloride are both used internationally in many oral-care and throat preparations, sold under a wide range of brand names and combinations. Other medications in the broader disinfectant and local-anaesthetic categories also exist, although individual products differ in formulation and intended use. To find a regional equivalent, search the active ingredients on Pill2Trip or ask a local pharmacist for guidance.

Should I consult a doctor before taking Calgel?

Yes. Although oral and throat-care preparations are sometimes available without prescription, regulatory status varies between countries and certain uses — particularly in young children with teething pain — have been the subject of changing guidance in different markets. A healthcare provider or pharmacist familiar with local rules and the patient's circumstances is the right person to advise on whether Calgel or an equivalent product is appropriate.