Bencidamina clorhidrato

Bencidamina clorhidrato Medicine

Overdose

Currently, cases of overdose of the drug Tantum are reported® Rose was not reported.

Contraindications

Hypersensitivity to any of the components of the drug.

Incompatibilities

No clinically significant interaction of the drug Tantum has been established® Rose with other drugs.

Undesirable effects

In rare cases, allergic reactions, dryness of the mucous membranes are possible.

Therapeutic indications

as a therapeutic and prophylactic agent for the prevention of postpartum infectious complications,

specific vulvovaginitis (in complex therapy),

non-specific vulvovaginitis and cervicovaginitis of any etiology, including those that have developed secondary to chemotherapy and radiotherapy,

bacterial vaginosis,

prevention of postoperative infectious complications in operative gynecology.

Pharmacotherapeutic group

  • Non-steroidal anti-inflammatory drug [Other non-narcotic analgesics, including non-steroidal and other anti-inflammatory drugs]

Pharmacodynamic properties

Benzidamine-NSAIDs, belongs to the group of indazoles. It has an anti-inflammatory and local analgesic effect, has an antibacterial, antifungal and antiseptic effect.

The mechanism of action of the drug is associated with the stabilization of cell membranes and inhibition of the synthesis of PG.

Benzidamine has an antibacterial effect due to the rapid penetration of microorganisms through the membranes, followed by damage to cell structures, disruption of metabolic processes and lysosomes of the cell.

It has an antifungal effect on Candida albicans. Causes structural modifications of the cell wall of fungi and their metabolic chains, i.e. prevents their reproduction, which was the basis for the use of benzidamine in inflammatory processes, including infectious etiology.

Pharmacokinetic properties

When applied topically, the drug is well absorbed through the mucous membranes and penetrates into inflamed tissues. The drug is excreted mainly by the kidneys and through the intestine in the form of metabolites or conjugation products.

Name of the medicinal product

Bencidamina Clorhidrato

Qualitative and quantitative composition

Benzydamine

Dosage (Posology) and method of administration

Intravaginal.

Contents of 1 pack. dissolve in 500 ml of boiled water. For a single douching, use 140 ml of the resulting solution. The prepared solution can be stored up to 5 days at room temperature. When re-applied, the solution must be heated to body temperature.

The procedure should be performed lying down, the liquid should remain in the vagina for several minutes.

In the postpartum period as a therapeutic and prophylactic agent to accelerate the process of rehabilitation and prevention of postpartum infectious complications: vaginal irrigation 1 time a day for 3-5 days.

In bacterial vaginosis: vaginal irrigation 1-2 times a day for 7-10 days.

In non-specific vulvovaginitis and cervicovaginitis of any etiology, including those that have developed secondarily against the background of chemotherapy and radiotherapy: 2 times a day for at least 10 days.

For specific vulvovaginitis (as part of complex therapy): 2 times a day for 3-5 days.

Prevention of postoperative infectious complications in operative gynecology: 1 time per day for 3-5 days.