Astaz-p (piperacillin,tazobactam)

Astaz-p (piperacillin,tazobactam) Medicine

Contraindications

Hypersensitivity (incl.other penicillins, cephalosporins and carbopenems).

Undesirable effects

Nausea, vomiting, diarrhea, allergic reactions (skin rash, itching, urticaria, erythema), rarely — transient increase in the blood of liver transaminases, alkaline phosphatase.

Therapeutic indications

Infection (среднетяжелого and heavy current) of the lower respiratory tract, абдоминальные, skin and soft tissues (including cellulitis, abscesses infected with trophic ulcers), pelvic organs (including endometritis), bacterial infection in patients with neutropenia, sepsis, severe infectious diseases, inflammatory diseases of the identification of the agent pathogenic.

Pharmacotherapeutic group

  • Penicillins in combinations

Pharmacodynamic properties

Active against (including beta-lactamase production) Gram-negative aerobic bacteria (E. coli, Citrobacter, Klebsiella, Enterobacter, Proteus, Pseudomonas aeruginosa and other Pseudomonas, N. gonorrhoeae, Haemophilus inf.), Gram-positive streptococci (S. pneumoniae, S. pyogenes, S. bovis, S. groups C and G), enterococci (E. faecalis, E. faecium), staphylococci (St. aureus, St. epidermidis), anaerobic microorganisms (Bacteroides, B. fragilis, B. ovatus, Fusobacteria).

Name of the medicinal product

Astaz-P (Piperacillin, Tazobactam)

Qualitative and quantitative composition

Piperacillin, Tazobactam

Dosage (Posology) and method of administration

In/(2.25 g dissolved in 5 ml of physiological saline or 5% solution of dextrose, or sterile water for injection), slowly, within 30 minutes Adults and children over 12 years of age — 2.25 g every 6 hours or 4.5 g every 8 hours (average daily dose — 12 g пиперациллина and 1.5 g of тазобактама), the patient lying in the on hemodialysis, — from 2.25 g every 8 h of course — from 7-10 days.