Antioxicaps

Overdose

Symptoms: nausea, vomiting, drowsiness, pallor of the skin.

Treatment: gastric lavage, administration of activated charcoal, symptomatic therapy.

Contraindications

hypersensitivity,

hypervitaminosis A and D,

children under 3 years old.

With caution: diabetes mellitus.

Incompatibilities

Ascorbic acid slows down the excretion of barbiturates, salicylates, and sulfonamides.

Pyridoxine hydrochloride increases the decarboxylation of levodopa in peripheral tissues.

Cardiac glycosides increase the risk of hypercalcemia caused by ergocalciferol.

Antiepileptic drugs increase the metabolism and excretion of ergocalciferol with bile.

Methotrexate, trimethoprim, pyrimethamine, triamterene, sulfasalazine, antiepileptic drugs reduce the absorption of folic acid (folate deficiency).

Laxative drugs, which include mineral oil and colestyramine, reduce the absorption of retinol palmitate, ergocalciferol and alpha-tocopherol acetate.

Biguanides reduce the absorption of cyanocobalamin.

Fluorouracil, vinblastine, bleomycin, cisplatin interfere with the absorption of retinol palmitate, thiamine mononitrate, pyridoxine hydrochloride.

Penicillamine, isoniazid reduce the effectiveness of thiamine mononitrate, increasing its excretion.

Isoniazid reduces the effectiveness of pyridoxine.

Oral contraceptives (estrogens) increase the concentration of retinol palmitate and ascorbic acid in the blood serum, reduce the concentration of folic acid.

Pharmaceutical form

Capsules

Undesirable effects

Allergic reactions to the components of the drug are possible.

Therapeutic indications

Treatment of amino acid deficiency and prevention of hypoavitaminosis resulting from various diseases (chronic liver disease, chronic kidney failure, in patients after surgery and cancer patients).

Pharmacotherapeutic group

  • Multivitamin preparation other preparations [Vitamins and vitamin-like preparations in combinations]
  • Multivitamin other preparations [Proteins and amino acids in combinations]

Pharmacodynamic properties

Moriamini® Forte makes up for the deficiency of vitamins and amino acids that are part of the drug.

Vitamins are an important part of the enzymatic systems of the main metabolic processes in the body. A well-balanced ratio of essential amino acids provides optimal conditions for their inclusion in protein biosynthesis. Hydroxyanthranilic acid hydrochloride, which is part of the preparation, is a factor that activates essential amino acids with the help of vitamins to participate in protein biosynthesis.

We need to take® Forte is a combined drug, the effect of which is due to the effects of vitamins and essential amino acids that make up its composition. Prevents the phenomena of vitamin deficiency, normalizes carbohydrate, protein and fat metabolism, stimulates the immune defense of the body, accelerates the recovery of performance after overwork, reduces the damaging effect of adverse environmental factors.

Ascorbic acid it is necessary to increase the body's resistance to infections. Provides the synthesis of collagen, helps to maintain the health of the skin. It affects the formation of Hb and the maturation of red blood cells.

Ergocalciferol regulates the exchange of calcium and phosphorus ions, the process of building the structure of bones, increases the absorption of calcium ions in the intestine, protein synthesis in the small intestine, liver and bones, the excretion of phosphates by the kidneys. It is necessary for the formation of fetal bone tissue.

Nicotinamide it stabilizes the processes of tissue respiration, fat and carbohydrate metabolism, and the xenobiotic metabolism system. Normalizes microcirculation. Participates in the processes of tissue respiration, fat and carbohydrate metabolism.

Pyridoxine hydrochloride as a coenzyme, it participates in the metabolism of amino acids and proteins, the synthesis of neurotransmitters.

Retinol Palmitate it is a necessary component for the normal function of the retina of the eye: it binds to opsin (the red pigment of the retina), forming the visual purple rhodopsin, necessary for visual adaptation in the dark. It is necessary for bone growth, normal reproductive function, embryonic development, for the regulation of division and differentiation of the epithelium (promotes the reproduction of epithelial cells of the skin and rejuvenation of the cell population, inhibits the processes of keratinization). It participates as a cofactor in various biochemical processes.

Riboflavin - a catalyst for the processes of cellular respiration and peroxidation of endogenous substances and xenobiotics, glucuronidation.

Thiamine Mononitrate - a precursor of cocarboxylase, which is a coenzyme in many biochemical reactions, participates in carbohydrate, protein and fat metabolism. The substance is necessary for the normal course of the processes of growth and development. Thiamine, being a water-soluble compound, is not stored in the body and does not have toxic properties.

Alpha-Tocopherol Acetate It has antioxidant properties, protects unsaturated fatty acids in the membranes from lipoperoxidation, participates in the formation of intercellular matter, collagen and elastic fibers of connective tissue, vascular smooth muscle, and the digestive tract. It has a positive effect on peripheral blood circulation.

Calcium Pantothenate It is an integral part of coenzyme A, participates in the processes of acetylation and oxidation of carbohydrates and fats, the synthesis of fatty acids and steroids from carbohydrates, in the implementation of the conjugation of glycolysis, the Krebs cycle and fat oxidation. It stimulates the regeneration of the epithelium and endothelium, promotes wound healing.

Cyanocobalamin together with folic acid, it participates in the synthesis of nucleotides, in the formation of red blood cells and nerve cells, and is necessary for the growth of the body.

Folic acid in the body, it is restored to tetrahydrofolic acid, which is a coenzyme involved in various metabolic processes. It stimulates erythropoiesis, participates in the synthesis of amino acids, nucleic acids, purines, pyrimidines, and choline metabolism.

We need to take® Forte contains 8 basic crystalline amino acids, 11 vitamins and an amino acid metabolite (hydroxyanthranilic acid hydrochloride) in a balanced proportion. The active ingredients are prepared in the form of 7 types of granules of different colors, to achieve maximum stability during storage and indifference to each other. Advanced granulation technology is used to achieve a slow, well-balanced release of active substances from individual granules. Due to this, the drug is characterized by good tolerability, a long period of effectiveness and convenient use.

Pharmacokinetic properties

The drug is absorbed mainly in the small intestine, with a bioavailability of about 98%, then the active components enter the liver, where one part of the essential amino acids participates in protein biosynthesis, the other part enters the blood as serum nutrients, changing the concentration of plasma amino acids, then is utilized, transformed or metabolized. The effect of the drug is the combined effect of its components, so it is not possible to conduct kinetic observations, since all the components together cannot be traced.

Name of the medicinal product

Antioxicaps

Qualitative and quantitative composition

Multivitamins

Dosage (Posology) and method of administration

Inside, children from 3 to 4 years — 1 capsule per day, for children over 4 years and adults-1-2 capsules. 3 times a day (granules can be dissolved in warm milk).

The course of treatment is at least 2 months and, if necessary, can be continued or repeated.

For prevention (based on the daily need), children from 3 to 12 years old are prescribed 1 capsule per day, children over 12 years old and adults-1-2 capsules per day.

The course of preventive treatment is at least 3 months and, if necessary, can be continued or repeated.