Analgin sopharma

Overdose

Symptoms: with prolonged use of the drug (more than 7 days) in large doses — nausea, vomiting, gastralgia, oliguria, hypothermia, decreased blood pressure, tachycardia, shortness of breath, tinnitus, drowsiness, delirium, impaired consciousness, agranulocytosis, hemorrhagic syndrome, acute renal and/or liver failure, convulsions, paralysis of the respiratory muscles.

Treatment: induce vomiting, perform gastric lavage, take saline laxatives, activated charcoal. In the conditions of a medical institution — forced diuresis, hemodialysis, with the development of convulsive syndrome-intravenous administration of diazepam and barbiturates.

Contraindications

Hypersensitivity to pyrazolone derivatives in the anamnesis, age (up to 3 months).

Incompatibilities

Solution for injection, Pills, rectal suppositories for children, Solution for intravenous and intramuscular administrationDropsTablet

The simultaneous use of Analgin with other non-narcotic analgesics can lead to a mutual increase in toxic effects.

Tricyclic antidepressants, oral contraceptives, and allopurinol disrupt the metabolism of metamizole in the liver and increase its toxicity.

Barbiturates and phenylbutazone weaken the effect of analgin.

Analgin enhances the effects of alcoholic beverages.

Radiopaque substances, colloidal blood substitutes and penicillin should not be used during treatment with metamizole.

Metamizole, displacing oral hypoglycemic drugs, indirect anticoagulants, corticosteroids and indomethacin from the protein bond, increases their activity.

Simultaneous use of Analgin with cyclosporine reduces the level of the latter in the blood. Thiamazole and sarcolysin increase the risk of developing leukopenia. The effect is enhanced by codeine, propranolol (slows down inactivation).

Sedatives and tranquilizers enhance the analgesic effect of analgin.

Increases chlorpromazine hypothermia.

Concomitant use of Analgin Sorhagmaa with other non-narcotic analgesics may lead to a mutual increase in toxic effects.

Tricyclic antidepressants, oral contraceptives, and allopurinol disrupt the metabolism of metamizole in the liver and increase its toxicity.

Barbiturates and phenylbutazone weaken the action of Analgin Sorhagma.

Analgin Sopharma enhances the effects of alcoholic beverages.

Radiopaque substances, colloidal blood substitutes and penicillin should not be used during treatment with metamizole.

Metamizole, displacing oral hypoglycemic drugs, indirect anticoagulants, corticosteroids and indomethacin from the protein bond, increases their activity.

The simultaneous use of Analgin Sorhagmaa with cyclosporine reduces the level of the latter in the blood. Thiamazole and sarcolysin increase the risk of developing leukopenia. The effect is enhanced by codeine, propranolol (slows down inactivation).

Sedatives and tranquilizers enhance the analgesic effect of Analgin Sorhagmaa.

Undesirable effects

Disorders of the gastrointestinal tract (nausea, vomiting, etc.), agranulocytosis, skin rashes, anaphylactic shock.

Therapeutic indications

Solution for injection, Pills, rectal suppositories for children, Solution for intravenous and intramuscular administrationDropsTablet

Pain syndrome of various etiologies:

headache,

migraine pain,

toothache,

neuralgia,

myalgia,

algodismenorrhea,

postoperative pain,

renal and biliary colic (in combination with antispasmodics),

feverish conditions in infectious and inflammatory diseases.

Moderate and severe pain (headache, toothache, dysmenorrhea), fever.

Pain syndrome of various etiologies:

headache,

migraine pain,

toothache,

neuralgia,

myalgia,

algodismenorrhea,

postoperative pain,

renal and biliary colic (in combination with antispasmodics),

feverish conditions in infectious and inflammatory diseases.

Pharmacotherapeutic group

  • NSAIDs-Pyrazolones

Pharmacodynamic properties

Metamizole sodium is a pyrazolone derivative. It has analgesic, antipyretic and weak anti-inflammatory effects, the mechanism of which is associated with the inhibition of the synthesis of PG. Pharmacological action develops in 20-40 minutes after taking the drug and reaches a maximum in 2 hours.

Name of the medicinal product

Analgin Sopharma

Qualitative and quantitative composition

Sodium Metamizole

Dosage (Posology) and method of administration

In / m or in / in — 2-5 ml 2-3 times a day.