Hypersensitivity to penicillins in the anamnesis.
Probenecid reduces renal excretion.
Gastrointestinal disorders (gastralgia, nausea, vomiting, diarrhea, allergic reactions (acute hypersensitivity reactions occur within 1-30 minutes after taking the drug).
Infections caused by staphylococci (resistant to benzylpenicillin), including infections of soft tissues (abscesses) and skin, bones (osteomyelitis) and joints, generalized infections.
Cloxacillin
The dosage varies depending on the type and severity of the infection. At the beginning of treatment in severe cases (septicemia, osteomyelitis), intravenous injections are usually used: adults and children are prescribed 80-100 mg/kg of body weight per day in 4 doses. Cloxacillin can also be administered in / m, but can not be administered as an intravenous infusion.